Results 21 to 30 of about 4,425 (166)

Machine learning identified MDK score has prognostic value for idiopathic pulmonary fibrosis based on integrated bulk and single cell expression data

Frontiers in Genetics, 2023
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that poses a significant challenge to medical professionals due to its increasing incidence and prevalence coupled with the limited understanding of its underlying molecular ...
Shichen Zhang, Lanlan Zhang, Lu Wang, Hongqiu Wang, Jiaxin Wu, Haoyang Cai, Chunheng Mo, Jian Yang   +7 more
doaj   +1 more source

The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice [PDF]

, 2006
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involved in inflammation-mediated angiogenesis which is important for wound healing and repair.
Scharffetter-Kochanek, K., Schruefer, R., Sulyok, S., Walzog, B., Peters, T., Schymeinsky, J.   +5 more
core   +1 more source

Efficacy of urinary midkine as a biomarker in patients with acute kidney injury [PDF]

, 2017
Background: The mortality and morbidity associated with acute kidney injury (AKI) remains high, despite advances in interventions. A multifunctional heparin-binding growth factor, midkine (MK), is involved in the pathogenesis of ischemic kidney injury ...
Ikematsu, Shinya, Nishiwaki, Kimitoshi, Matsuo, Seiichi, Asano, Naoko, Nishimura, Kunihiro, Kosugi, Tomoki, Sato, Waichi, Yuzawa, Yukio, Hayashi, Hiroki, Sugiyama, Daisuke, Kadomatsu, Kenji, Komori, Kimihiro, Maruyama, Shoichi   +12 more
core   +1 more source

Evaluation of Midkine Expression in Dentigerous Cysts, Odontogenic Keratocysts and Different Types of Ameloblastoma [PDF]

Türk Patoloji Dergisi, 2018
Objective: Midkine is a heparin-binding growth factor whose expression is increased in most tumors, namely ameloblastomas. This study aimed to compare Midkine expression in different odontogenic lesions.
Naghmeh JEIROODI, Mahshid BAGHERPOUR, Razieh ZARE, Shima TORABİ ARDAKANI, Azadeh ANDISHEH TADBIR   +4 more
doaj   +1 more source

The circulating midkine in the newly diagnosed celiac disease: Clinical implications

Advanced Biomedical Research, 2021
Background: Celiac disease (CeD) is a chronic inflammatory small intestine disorder caused by an abnormal immune response to an array of the epitopes of the wheat gluten and related proteins of rye and barley in genetically susceptible individuals ...
Mohammad Hassan Emami, Shima Soltani, Nahid Eskandari, Mohsen Masjedi   +3 more
doaj   +1 more source

Estimation of midkine levels in serum and gingival crevicular fluid in smokers and non-smokers of chronic gingivitis patients – A clinico-biochemical study

Journal of Dr. NTR University of Health Sciences, 2018
Objectives: To detect the presence of Midkine in serum and gingival crevicular fluid (GCF) of healthy non-smokers, chronic gingivitis smokers, and non-smoker individuals and to evaluate the role of Midkine in the progression of gingival inflammation ...
Dandu Subramanyam Madhu Babu, Sundeep Narahari, Vineetha Vemuri, Egatela Prasuna, Dandu Siva Sai Prasad Reddy, Nagireddy Ravindra Reddy   +5 more
doaj   +1 more source

Midkine as a driver of age-related changes and increase in mammary tumorigenesis [PDF]

Cancer Cell
Kornélia Polyak
exaly   +2 more sources

The role of midkine in health and disease

Frontiers in Immunology, 2023
Midkine (MDK) is a neurotrophic growth factor highly expressed during embryogenesis with important functions related to growth, proliferation, survival, migration, angiogenesis, reproduction, and repair.
Emely Elisa Neumaier, Veit Rothhammer, Mathias Linnerbauer   +2 more
doaj   +1 more source

Role of Serum Midkine Level as a Diagnostic Biomarker for Very Early and Early Hepatocellular Carcinoma [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2017
Background and study aim: AFP is the most commonly utilized biomarker for HCC although it has a low sensitivity and specificity for the disease. New biomarkers with better sensitivity and specificity are to be studied. The aim of this work is to evaluate
Amal Zidan, Ibrahim Ibrahim, Maysaa Saeed   +2 more
doaj   +1 more source

Integrating single-cell RNA-seq and spatial transcriptomics reveals MDK-NCL dependent immunosuppressive environment in endometrial carcinoma

Frontiers in Immunology, 2023
ObjectivesThe tumor microenvironment (TME) play important roles in progression of endometrial carcinoma (EC). We aimed to assess the cell populations in TME of EC.MethodsWe downloaded datasets of single-cell RNA-seq (scRNA-seq) and spatial transcriptome (
Xinnian Yu, Linjun Xie, Jianjuan Ge, Huixin Li, Shanliang Zhong, Xiaolin Liu   +5 more
doaj   +1 more source