Results 51 to 60 of about 4,425 (166)
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis
Arthritis Research & Therapy, 2018 Background Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is one of the leading causes of death in SSc. Identification of a serum-based proteomic diagnostic biomarker for SSc-PAH would allow for rapid non-invasive screening and ...
Lisa M. Rice +9 more
doaj +1 more source
European Journal of Inflammation, 2020 Midregional pro-adrenomedullin (MR-proADM), midkine, and stromelysin2 (ST2) are novel cardiac biomarkers associated with heart failure and atherosclerotic diseases like stable ischemic disease and acute coronary syndrome.
Zhong Chen, Yawen Zhu, Lili Zhang
doaj +1 more source
Marine Drugs, 2022 Different classes of phytochemicals were previously isolated from the Red Sea algae Hypnea musciformis as sterols, ketosteroids, fatty acids, and terpenoids. Herein, we report the isolation of three fatty acids—docosanoic acid 4, hexadecenoic acid 5, and
Sameh S. Elhady +13 more
doaj +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Equine Veterinary Journal, EarlyView.Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Midkine secretion protects Hep3B cells from cadmium induced cellular damage
, 2008 Aim: To evaluate role of midkine secretion during Cadmium (Cd) exposure in the human hepatocyte cell line Hep3B cells. Methods: Different dosages of Cd (0.5-1-5-10 μg/mL) were applied to Hep3B cells and their effects to apoptosis, lactate dehydrogenase ...
Ataoğlu, Haluk +3 more
core +1 more source
Serum Midkine as a Biomarker for Hepatocellular Carcinoma Treatment Response and Prognostication
Journal of Clinical Laboratory Analysis, EarlyView.Up‐to‐date, tumor markers are considered more helpful in the evaluation of treatment response and prognostication rather than diagnosis. Identifying a valid biomarker to help clinical management of hepatocellular carcinoma (HCC) is still a challenge, especially the alpha‐fetoprotein (AFP) negative HCC. This study evaluated the efficacy of serum Midkine
Yanfang Luo +3 more
wiley +1 more source
ALK activation, ligands and therapeutic targets in glioblastoma and other cancers
Frontiers in Oncology, 2012 The intracellular anaplastic lymphoma kinase (ALK) fragment shows striking homology with members of the insulin receptor family and was initially identified as an oncogenic fusion protein resulting from a translocation in lymphoma and more recently in a ...
Anton eWellstein
doaj +1 more source
Cancer Science, EarlyView.Spatial transcriptomics and bulk RNA‐seq data analysis revealed the molecular characteristics of invasive lobular carcinoma (ILC). ILC was classified into three clusters: proliferative, immunoreactive, and stromal‐rich, with different prognoses. ABSTRACT Invasive lobular carcinoma (ILC) is a special type of breast cancer.
Momoko Tokura +9 more
wiley +1 more source
, 2011 G different levels of midkine expression, Ad5GFP alone, or the vehicle. (B) Adenoviral hexon staining. HEK293 cells were treated with preparations of Ad5MK-infected pancreatic cancer cells.
Tatsuo Ito (95905) +12 more
core +1 more source
Cellular expression of midkine-a and midkine-b during retinal development and photoreceptor regeneration in zebrafish [PDF]
, 2009 In the retina of adult teleosts, stem cells are sustained in two specialized niches: the ciliary marginal zone (CMZ) and the microenvironment surrounding adult MÜller glia.
Thomas S. Vihtelic +10 more
core +1 more source