Results 41 to 50 of about 160,178 (309)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

2015 Migrant Crisis as a Stimulus for EU’s Modern Regulatory Policy Reconsidering: Management and Security Dimensions

open access: yesІсторико-політичні проблеми сучасного світу, 2017
The body of the article goes on to discuss the migration and refugee policy issues that went viral in media, as well as became widely discussed by experts and EU power-holding structures.
Volodymyr Fisanov
doaj   +1 more source

Population mobility in the Commonwealth of independent states: Whither common migration policy? CARIM-East research report [PDF]

open access: yes, 2014
This working paper reviews trends in population and labour migration between countries comprising the Commonwealth of Independent States (CIS) and Georgia, which account for most of the population and territory of the former USSR (FUSSR).
Chudinovskikh, Olga, Denisenko, Mikhail
core  

A visible geography of invisible journeys: Central American migration and the politics of survival [PDF]

open access: yes, 2018
Human rights groups have called undocumented Central American migrants the ‘invisible victims’ of criminal violence in Mexico. However, the geography of the unauthorised migration route through Mexico is highly visible; its location, protocols and ...
Brigden, Noelle K.
core   +2 more sources

Each Step during Transendothelial Migration of Flowing Neutrophils is Regulated by the Stimulatory Concentration of Tumour Necrosis Factor-α [PDF]

open access: yesCell Adhesion and Communication, 1998
Migration of circulating neutrophils occurs in several steps: capture and rolling adhesion are followed by activation of beta 2-integrins and immobilisation, and then neutrophils move over and through the endothelium. However, it is not clear how the underlying mechanisms and completion of each step depend on the concentration of stimulatory cytokines ...
P, Bahra   +4 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Human rights in the EU return policy: the case of the EU-Albania relations [PDF]

open access: yes, 2012
The examination of the approach of the EU return policy to Albania - a country to which the EU returns about one fifth of the total number of the third country nationals removed - demonstrates that the predominant focus of the EU return policy on the ...
Dedja, Sokol
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

SOCIO-ECONOMIC AND POLITICAL-LEGAL ASPECTS OF POST-CRISIS MIGRATION

open access: yesФинансы: теория и практика, 2017
The paper deals with the socio-economic and political-legal aspects of the post-crisis migration over time between 2012 and the first half of 2016 based on the data of the Automated Analytical Reporting System (AARS) of the Federal Migration Service, the
M. L. Galas
doaj   +1 more source

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