Эндотелиопротекторное действие милдроната и его производных при моделировании L-NAME индуцированного дефицита оксида азота [PDF]
, 2011 Результаты исследования 4 химических производных пропионата на лабораторных крысахyesБелгородский государственный ...
Даниленко, Л. М. +4 more
core +1 more source
Meldonium: drug which brought disrepute to sport [PDF]
, 2017 World of sports have been rocked by doping scandals every now and then and World Anti-Doping Agency(WADA) has banned several offending drugs at different times to counter this menace.
Das, Smita +2 more
core +2 more sources
Rat spinal ganglia in assessment of protective action of antioxidants: A morphological study
Medicina, 2017 Background and objective: Mercury pollution is one of the most pressing environmental problems. Therefore, the impact of mercury on human body, the nervous system in particular, remains topical.
Liudmyla M. Sokurenko +4 more
doaj +1 more source
Изучение противоишемической активности в ряду производных 3-(2, 2, 2-триметилгидразиний) пропионата при моделировании коронароокклюзионного инфаркта миокарда [PDF]
, 2011 Результаты экспериментального исследования влияния 3-(2, 2, 2-триметилгидразиний) пропионата и его производных на площадь некротизированного миокарда левого желудочка при моделировании коронароокклюзионного инфаркта миокардаyesБелгородский ...
Даниленко, Л. М. +4 more
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Mildronate treatment alters γ-butyrobetaine and l -carnitine concentrations in healthy volunteers [PDF]
, 2011 Objectives In this study, we aimed to investigate the effects of long-term administration of the cardioprotective drug mildronate on the concentrations of l-carnitine and γ-butyrobetaine in healthy volunteers.
Bieber +40 more
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Mildronate improves cognition and reduces amyloid‐β pathology in transgenic Alzheimer's disease mice [PDF]
Journal of Neuroscience Research, 2013 Mildronate, a carnitine congener drug, previously has been shown to provide neuroprotection in an azidothymidine‐induced mouse model of neurotoxicity and in a Parkinson's disease rat model. The aim of this study was to investigate the effects of mildronate treatment on cognition and pathology in Alzheimer's disease (AD) model mice (APPSweDI ...
Ulrika, Beitnere +5 more
openaire +2 more sources
Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice [PDF]
, 2014 BACKGROUND: Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis.
David Sedmera +6 more
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Влияние медикаментозной терапии на клиническое и психоэмоциональное состояние больных с хронической сердечной недостаточностью и сохраненной фракцией выброса [PDF]
, 2018 На сегодняшний день отсутствуют результаты исследований, демонстрирующие снижение смертности на фоне лечения больных с хронической сердечной недостаточностью (ХСН) и сохраненной фракцией выброса, при этом данный синдром остается ведущей причиной ...
Вихрова, Т.А. +3 more
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Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats [PDF]
, 2009 Background and purpose: Mildronate [3-(2,2,2-trimethylhydrazinium) propionate] is an anti-ischaemic drug whose mechanism of action is based on its inhibition of L-carnitine biosynthesis and uptake.
Azuma +28 more
core +1 more source
COMPARATIVE EFFECTIVENESS OF CARDIOCYTE PROTECTORS IN COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION
Российский кардиологический журнал, 2009 The study investigated the effects of cardiocyte protectors, mexicor and mildronate, in combination with ACE inhibitors, on blood levels of lipid peroxidation products, vascular endothelial function, circadian profile of blood pressure, and left ...
F. E. Khlebodarov +2 more
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