Results 51 to 60 of about 938,722 (212)

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Enzymatic activity of Bacillus paralicheniformis T7 strain and its application in cheese production

Еуразиялық агротехникалық журнал
Background and Aim. The increasing demand for inexpensive milk coagulants stimulates the search for new sources of milk-forming enzymes among proteolytic microorganisms. The aim of this work was to isolate a strain with proteolytic activity.
Saniya Aktayeva, Annelya Tursunbekova, Arman Mussakhmetov, Karina Maksutova, Aiida Ussenbay, Bekbolat Khassenov   +5 more
doaj   +1 more source

Etude comparative des coagulations du lait par actions de l'extrait des écorces de l'Ongokea gore et des enzymes coagulants bien connus [PDF]

Tropicultura, 2008
Milk Clotting Using Ongokea gore Bark Extract Compared to those Obtained to Well Known Milk Clotting Extracts. The evolution of firmness in curd obtained using plant extract (Ongokea gore barks) and that using renounce coagulating enzymes (bovine pepsin,
Libouga, DG.
doaj  

Evaluation of the milk clotting potential and characterization of proteases from Aspergillus sp. and Pleurotus albidus

Acta Scientiarum: Technology, 2022
The study evaluated the production of proteases in solid-state fermentation using wheat bran as a substrate. The best producing isolates were used to obtain crude extract which was evaluated for optimal pH and temperature, thermostability, effect of ...
Mariene Marques Nolli, Alex Graça Contato, Tatiane Brugnari, Ana Júlia dos Reis Buzzo, Guilherme Mauro Aranha, Fabí­ola Dorneles Inácio, Rosane Marina Peralta, Cristina Giatti Marques de Souza   +7 more
doaj   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

Advanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong, Haitao Wu, Weitao Wang, Xuan Zhang, Qian Chen, Yaoyu Hu, Zhengbao Zha   +6 more
wiley   +1 more source

Optimization of a portable NIR device for the optical supervision of milk coagulation process [PDF]

, 2011
The coagulation of milk is the fundamental process in cheese-making, which is based on a gel formation as consequence of physicochemical changes taking place in the casein micelles.
Chamorro Valencia, M. Concepcion, Correa Hernando, Eva Cristina, Moreno Lucas, Beatriz, Barreiro Elorza, Pilar   +3 more
core  

Effect of coagulants from aerial parts of Tunisian Moringa oleifera on cheese properties

Acta Scientiarum: Technology
The present study aimed to produce vegetable clotted cheese using coagulants from aerial parts of Tunisian Moringa oleifera as calf rennet substitute.
Maha Bergaoui, Imen Mahmoudi, Aida Karray, Olfa Ben Moussa, Nawres Dachraoui, Mnasser Hassouna, Mouna Boulares   +6 more
doaj   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Identification of milk clotting activity from different sources of plant’s proteolytic enzymes / Siti Nursyafiqah Mohammad Zilan [PDF]

, 2018
Traditional bovine rennet used for cheese processing was high cost and limited in resource. A study was done to find replacement of the curdling activity of milk using different sources of plant’s proteolytic enzymes which are bromelain enzyme from the ...
Mohammad Zilan, Siti Nursyafiqah
core