Results 61 to 70 of about 26,469 (297)

Increased pulsation ratio in rear quarters reduces machine-on time and milking on empty teats

open access: yesJournal of Dairy Science
: Dairy cows usually store more milk in the rear quarters of the udder than the front quarters. With conventional machine milking, this leads to an earlier cessation of milk flow in front quarters than the rear quarters and hence unavoidable milking on ...
Patricia Fürst   +3 more
doaj   +1 more source

Análise econômica de esquemas alternativos de controle leiteiro Economic analysis of alternative schemes of milk recording

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Compararam-se os custos de seis esquemas de controle leiteiro (CL), estabelecidos com base em diferentes freqüências de controles (com possibilidade de controle trimestral supervisionado e aproveitamento do CL da fazenda), no número de ordenhas e na ...
V.L. Cardoso   +5 more
doaj   +1 more source

Analysis of Fluoride Content in Alternative Milk Beverages [PDF]

open access: yesJournal of Clinical Pediatric Dentistry, 2019
Background: The dentist has a responsibility to provide nutritional counseling and fluoride consumption recommendations. The purpose of this study was to measure and compare the concentrations of fluoride in a large number of alternative milk beverages and bovine milk.
Janice A, Townsend   +6 more
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

TWAS revealed significant causal loci for milk production and its composition in Murrah buffaloes

open access: yesScientific Reports, 2023
Milk yield is the most complex trait in dairy animals, and mapping all causal variants even with smallest effect sizes has been difficult with the genome-wide association study (GWAS) sample sizes available in geographical regions with small livestock ...
Supriya Chhotaray   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Milk: An Alternative Beverage for Hydration?

open access: yesFood and Nutrition Sciences, 2015
The hydration status of a physically active individual or athlete can influence his/her physical or mental performance. The degree of hypohydration may lead to serious health problems, and consequently to impair athletic performance. The consumption of water or carbohydrate-electrolyte beverages before, during and after exercise is essential to ...
Cássia Pegoretti   +3 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The effect of the biohydrogenation-induced milk fat depression in dairy cows on milk odd- and branched-chain fatty acids across multiple studies

open access: yesJournal of Dairy Science
: Diet-induced milk fat depression (MFD) caused by UFA and low-fiber diets results in an increase in alternate rumen biohydrogenation intermediates. The effect of these MFD-inducing diets on milk odd- and branched-chain fatty acids (OBCFA) is not well ...
M. Arif   +4 more
doaj   +1 more source

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