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Biotechnological production of human milk oligosaccharides
Biotechnology Advances, 2012Human milk contains a large variety of oligosaccharides (HMOs) that have the potential to modulate the gut flora, affect different gastrointestinal functions, and influence inflammatory processes. This review introduces the recent advances in the microbial and coupled enzymatic methods to produce HMOs with grouping them into trisaccharides ...
Nam Soo Han +2 more
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Oligosaccharides of Human Milk
Nature, 1957THE presence of fucose as a constituent sugar in oligosaccharides obtained from human milk was reported by Kuhn1 in 1952. Since that time Kuhn and his associates have characterized four oligosaccharides from this source, in all of which fucose is found: a trisaccharide, fucosido-lactose; two pentasaccharides referred to as lacto-N-fucopentaoses I and ...
F H, MALPRESS, F E, HYTTEN
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2022
The carbohydrate fraction of mammalian milk is constituted of lactose and oligosaccharides, most of which contain a lactose unit at their reducing ends. Although lactose is the predominant saccharide in the milk of most eutherians, oligosaccharides significantly predominate over lactose in the milk of monotremes and marsupials.This review describes the
Tadasu, Urashima +4 more
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The carbohydrate fraction of mammalian milk is constituted of lactose and oligosaccharides, most of which contain a lactose unit at their reducing ends. Although lactose is the predominant saccharide in the milk of most eutherians, oligosaccharides significantly predominate over lactose in the milk of monotremes and marsupials.This review describes the
Tadasu, Urashima +4 more
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The Journal of nutrition, 2007
Feeding infants breast milk of healthy mothers is associated with a lower incidence of infectious and allergic diseases. Although this effect is of multifactorial origin, it is widely accepted that the entire intestinal flora of breast-fed infants provides antiinfective properties and is an important stimulating factor for the postnatal development of ...
Boehm, G (Günther), Stahl, B
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Feeding infants breast milk of healthy mothers is associated with a lower incidence of infectious and allergic diseases. Although this effect is of multifactorial origin, it is widely accepted that the entire intestinal flora of breast-fed infants provides antiinfective properties and is an important stimulating factor for the postnatal development of ...
Boehm, G (Günther), Stahl, B
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Journal of Pediatric Gastroenterology and Nutrition, 2016
Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
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Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
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2001
Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney +4 more
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Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney +4 more
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Human milk oligosaccharides: Only the breast
Journal of Paediatrics and Child Health, 1997Abstract: Over 100 years ago it was first deduced that a major component of human milk must be an unidentified carbohydrate that was not found in cows milk. At first this was thought to be a form of lactose and was called gynolactose. We now know that this was not a single carbohydrate but a complex mixture of approximately 130 different ...
P, McVeagh, J B, Miller
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Trends in food science & technology, 2019
Background: Milk oligosaccharides are compounds capable of modulating intestinal microbiota by exerting a prebiotic, anti-adhesive and anti-inflammatory effect. Technological advances in equipment and analytical methods have indicated that goat milk is a good source of oligosaccharides, and that some of these oligosaccharides are similar to those found
Sousa, Yasmim R. F. +3 more
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Background: Milk oligosaccharides are compounds capable of modulating intestinal microbiota by exerting a prebiotic, anti-adhesive and anti-inflammatory effect. Technological advances in equipment and analytical methods have indicated that goat milk is a good source of oligosaccharides, and that some of these oligosaccharides are similar to those found
Sousa, Yasmim R. F. +3 more
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Immunomodulatory Effects of Breast Milk Oligosaccharides
2005Breast milk oligosaccharides are excreted in urine in amounts that suggest that they may exist in the circulation at levels compatible with a physiological function. Some oligosaccharides have structural similarity to cellular adhesion molecules and may influence adhesion of cells in breast fed infants.
N, Klein +4 more
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