Results 141 to 150 of about 45,700 (265)

Glucocorticoid and mineralocorticoid receptors regulate paracellular permeability in a primary cultured gill epithelium [PDF]

, 2011
Scott P. Kelly, Helen Chasiotis
openalex   +1 more source

Guideline‐directed medical therapy after revascularization and outcomes in ischaemic cardiomyopathy

ESC Heart Failure, EarlyView.
Among patients with ischaemic heart failure undergoing revascularisation, those receiving GDMT had lower unadjusted mortality rates. The combination of GDMT and CABG was associated with the best long‐term outcomes. In real‐world practice, the use of GDMT increased over time, reflecting a growing emphasis on guideline‐based therapy even after ...
Carlos Moliner‐Abós, Maria Calvo‐Barceló, Eduard Solé‐Gonzalez, Andrea Borrellas Martín, Paula Fluvià Brugués, Jesus Sánchez Vega, Joan Vime Jubany, Maria Ferré Vallverdú, Manel Taurón Ferrer, Pablo Eduardo Tobias Castillo, Juan Carlos de la Fuente Mancera, Pau Vilardell Rigau, Rosa Vila Olives, Carles Diez López, Antoni Bayés‐Genís, Dabit Arzamendi Aizpurua, Ignacio Ferreira González, Sònia Mirabet Pérez   +17 more
wiley   +1 more source

Initiation of SGLT2 inhibitors versus mineralocorticoid receptor antagonists as third-line therapy in heart failure with reduced ejection fraction: a nationwide cohort study. [PDF]

Lancet Reg Health Eur
Svanström H, Mkoma GF, Hviid A, Pasternak B.   +3 more
europepmc   +1 more source

Modulation of Immunity and Inflammation by the Mineralocorticoid Receptor and Aldosterone [PDF]

, 2015
Natalia Muñoz‐Durango, Andrea Vecchiola, Luis M González-Gómez, Felipe Simón, Claudia A. Riedel, Carlos Fardella, Alexis M. Kalergis   +6 more
openalex   +1 more source

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

European Journal of Heart Failure, EarlyView.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo, Emmanuel Bresso, Kenneth Dickstein, Bertram Pitt, John G.F. Cleland, Stefan D. Anker, Carolyn S.P. Lam, Mandeep R. Mehra, Dirk J. van Veldhuisen, Barry Greenberg, Faiez Zannad, Nicolas Girerd   +11 more
wiley   +1 more source

Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists

The Journal of Clinical Investigation
Mineralocorticoid excess commonly leads to hypertension (HTN) and kidney disease. In our study, we used single-cell expression and chromatin accessibility tools to characterize the mineralocorticoid target genes and cell types.
Amin Abedini, Andrea Sánchez-Navaro, Junnan Wu, Konstantin A. Klötzer, Ziyuan Ma, Bibek Poudel, Tomohito Doke, Michael S. Balzer, Julia Frederick, Hana Cernecka, Hongbo Liu, Xiujie Liang, Steven Vitale, Peter Kolkhof, Katalin Susztak   +14 more
doaj   +1 more source

Methodological issues in outpatient worsening heart failure research

ESC Heart Failure, EarlyView.
Karim Hnid
wiley   +1 more source

Mineralocorticoid effects of fludrocortisone and hydrocortisone in primary adrenal insufficiency: EU-AIR patient data. [PDF]

J Endocrinol Invest
Ekman B, Quinkler M, Zhang P, Isidori AM, Murray RD, Wahlberg J, EU-AIR investigators.   +6 more
europepmc   +1 more source

Exogenous corticosteroid-induced modulation of RAAS: potential implications for septic shock biomarker analysis. [PDF]

Ann Intensive Care
Uslar T, Sanfuentes B, Baudrand R, Hernández G, Kattan E.   +4 more
europepmc   +1 more source

Overactivation of the Aldosterone^|^frasl;Mineralocorticoid Receptor System in Metabolic Syndrome and its Implication in Cardiac and Kidney Injury

, 2012
Miki Nagase
openalex   +2 more sources