Results 111 to 120 of about 59,126 (309)

Epidemiology of hospitalized heart failure in France based on national data over 10 years, 2012–2022

ESC Heart Failure, Volume 12, Issue 2, Page 1283-1294, April 2025.
Abstract Aims We aim to describe the incidence of HF hospitalization in France in the post‐pandemic era, the prevalence of HF cases and patients' characteristics, management and outcomes while focusing on sex, age and socio‐economic differences and to analyse time‐trends between 2012 and 2022.
Valérie Olié, Richard Isnard, Françoise Pousset, Clémence Grave, Jacques Blacher, Amélie Gabet   +5 more
wiley   +1 more source

Myosin Light Chain Phosphatase Plays an Important Role in Cardiac Fibrosis in a Model of Mineralocorticoid Receptor‐Associated Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Myosin phosphatase targeting subunit 2 (MYPT2) is an important subunit of cardiac MLC (myosin light chain) phosphatase, which plays a crucial role in regulating the phosphorylation of MLC to phospho‐MLC (p‐MLC).
Zhe Ye, Ryuji Okamoto, Hiromasa Ito, Rie Ito, Keishi Moriwaki, Mizuki Ichikawa, Lupiya Kimena, Yusuf Ali, Masaaki Ito, Celso E. Gomez‐Sanchez, Kaoru Dohi   +10 more
doaj   +1 more source

Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury

Frontiers in Physiology, 2019
Acute skeletal muscle injury is followed by a temporal response of immune cells, fibroblasts, and muscle progenitor cells within the muscle microenvironment to restore function.
J. Spencer Hauck, Zachary M. Howard, Jeovanna Lowe, Neha Rastogi, Madison G. Pico, Sarah A. Swager, Jennifer M. Petrosino, Jennifer M. Petrosino, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Federica Accornero, Federica Accornero, Jill A. Rafael-Fortney   +12 more
doaj   +1 more source

Physiological monitoring in the complex multi-morbid heart failure patient - Introduction. [PDF]

, 2019
Repeated physiological monitoring of comorbidities in heart failure (HF) is pivotal. This document introduces the main challenges related to physiological monitoring in the complex multimorbid HF patient, arising during an ESC consensus meeting on this ...
Rosano, GMC, Seferović, PM
core   +1 more source

Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction

ESC Heart Failure, Volume 12, Issue 2, Page 912-922, April 2025.
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi, Matteo Pagnesi, Rossana Corso, Antonio M. Sammartino, Daniela Tomasoni, Riccardo M. Inciardi, Carlo M. Lombardi, Marianna Adamo, Savina Nodari, Marco Metra   +9 more
wiley   +1 more source

Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Diastolic Dysfunction in Preclinical Nondiabetic Chronic Kidney Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The mineralocorticoid receptor plays a significant role in the development of chronic kidney disease (CKD) and associated cardiovascular complications.
Ixchel Lima Posada, Matthieu Soulié, Yohan Stephan, Roberto Palacios Ramirez, Benjamin Bonnard, Lionel Nicol, Bertram Pitt, Peter Kolkhof, Paul Mulder, Frederic Jaisser   +9 more
doaj   +1 more source

Steroid Receptors and Vertebrate Evolution

, 2019
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago.
Baker, Michael E.
core  

Myeloid Mineralocorticoid Receptor Activation Contributes to Progressive Kidney Disease [PDF]

, 2014
Louis Huang, David J. Nikolic‐Paterson, Yingjie Han, Elyce Ozols, Y. Frank, Morag J. Young, Greg H. Tesch   +6 more
openalex   +1 more source

Prognostic impact of iron deficiency in new‐onset chronic heart failure: Danish Heart Failure Registry insights

ESC Heart Failure, Volume 12, Issue 2, Page 1346-1357, April 2025.
Abstract Aims Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all‐cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new‐onset chronic HF.
Abdullahi Ahmed Mohamed, Daniel Mølager Christensen, Milan Mohammad, Christian Torp‐Pedersen, Lars Køber, Emil Loldrup Fosbøl, Tor Biering‐Sørensen, Morten Lock Hansen, Mariam Elmegaard Malik, Nina Nouhravesh, Charlotte Anderrson, Morten Schou, Gunnar Gislason   +12 more
wiley   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E., Vandermosten, Leen, Vanhorebeek, Ilse   +4 more
core   +1 more source