Results 161 to 170 of about 35,682 (244)

Mineralocorticoid receptor antagonists in heart failure: a systematic review and meta-analysis. [PDF]

Front Cardiovasc Med
Zhang Y, Bao YC, Wang LX, Zhao HJ, Sun J, Sun L, Duan W, Du M, Wang LJ, An QY, Yang WZ.   +10 more
europepmc   +1 more source

Multi‐Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7416-7429, August 2026.
ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim, Salma Qassin, Lucy McKenna, Emma Hornsey, Dominic Italiano, Leonid Churilov, Richard J. MacIsaac, Jas‐mine Seah, Elif I. Ekinci, The Austin EMPA‐MRI Study Group   +9 more
wiley   +1 more source

Mineralocorticoid receptor phase separation modulates cardiac preservation. [PDF]

Nat Cardiovasc Res
Lei I, Sicim H, Gao W, Huang W, Noly PE, Pergande MR, Wilson MC, Lee A, Liu L, Abou El Ela A, Jiang M, Saddoughi SA, Pober JS, Platt JL, Cascalho M, Pagani FD, Chen YE, Pitt B, Wang Z, Mortensen RM, Ge Y, Tang PC.   +21 more
europepmc   +1 more source

Potassium binders and continuation of renin–angiotensin system inhibitors/mineralocorticoid receptor antagonist in chronic kidney disease and heart failure (the DEMONSTRATE database)

Journal of Internal Medicine, Volume 300, Issue 2, Page 179-192, August 2026.
Abstract Introduction Hyperkalaemia is a serious complication in patients with chronic kidney disease (CKD) and heart failure (HF), often leading to the discontinuation of renin–angiotensin–aldosterone system inhibitors (RAASi; renin‐angiotensin system inhibitors [RASi] and mineralocorticoid receptor antagonists [MRAs]) despite their cardiorenal ...
Hans Furuland, Anders Olof Larsson, Milica Uhde, Kristel Parv, Matilda Almstedt, Thomas Cars, Maria K. Svensson   +6 more
wiley   +1 more source

Mineralocorticoid receptor antagonists promote renal immunosenescence. [PDF]

Int Urol Nephrol
Wang QR, Yang Y.
europepmc   +1 more source

Amiodarone‐related thyroid dysfunction and associated outcomes in patients with heart failure—A nationwide cohort study

Journal of Internal Medicine, Volume 300, Issue 2, Page 204-212, August 2026.
Abstract Aim Amiodarone increases the risk of thyroid dysfunction, but the prognostic significance of this complication in patients with heart failure (HF) is uncertain. This study investigates the association between amiodarone‐related thyroid dysfunction and risk of HF hospitalization or death in a nationwide cohort.
Søren Lund Kristensen, Sam Aiyad Ali, Mads Ersbøll, Jawad Haider Butt, Rasmus Rørth, Lucas Malta Westergaard, Lauge Østergaard, Finn Gustafsson, Oren Caspi, Emil Fosbøl, Lars Køber, Christian Selmer   +11 more
wiley   +1 more source

The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice. [PDF]

Int J Mol Sci
Ali A, Fossas De Mello N, Luo Y, Bensreti H, Melynk S, Shaver JC, Choudhary V, McGee-Lawrence ME, Bollag WB.   +8 more
europepmc   +1 more source

Intermittent Fasting Exerts Antidepressant‐Like Effects by Restoring HPA Axis Homeostasis Through Coordinated GR–MR Signaling

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Intermittent fasting (IF) exerts antidepressant‐like effects by restoring impaired cooperative signaling between glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), thereby modulating hypothalamic neurocircuit activity and reinstating HPA axis homeostasis.
Miaomiao Tang, Qihan Sun, Jinfang Song, Xinmiao Piao, Zihui Geng, Xu Han, Runxin Li, Yue Li, Mengyi Han, Ranji Cui, Bingjin Li   +10 more
wiley   +1 more source

Mineralocorticoid receptor antagonists for acute myocardial infarction: a systematic review and meta-analysis of randomised controlled trials. [PDF]

Open Heart
Ang SP, Chia JE, Lima BB, Iglesias J, Lee E, Krittanawong C, Alam M, Mukherjee D.   +7 more
europepmc   +1 more source

Nonsteroidal mineralocorticoid receptor antagonists and cardiovascular events in type 2 diabetes: a retrospective study. [PDF]

Eur Heart J Cardiovasc Pharmacother
Chen YH, Fang YW, Chen MT, Liou HH, Tsai MH.   +4 more
europepmc   +1 more source