BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Origin minimally processed foods Plant and Bioconservation
There is currently a worldwide trend towards greater consumption of fresh foods with a lower proportion of chemical additives, safe, sensorially acceptable and of high nutritional value; technologies have emerged in the production of this type of food called minimally processed foods. However, the consumption of fresh or minimally processed foods poses
Alejandro De Jesús Cortés Sánchez +1 more
openaire +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Correction to: Effectiveness of a minimally processed food-based nutritional counselling intervention on weight gain in overweight pregnant women: a randomized controlled trial. [PDF]
Sartorelli DS +11 more
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Pod pojmom „minimalno procesirana hrana“ podrazumijeva se hrana visoke kakvoće kojoj su sačuvane originalne organoleptičke i nutritivne značajke sirovine, zbog blažih uvjeta primjenjenih pri njenom procesiranju.Zajednička karakteristika svim ovim ...
Šarić, Tanja
core +2 more sources
Background: Consuming ultra-processed foods may increase exposure to phthalates, a group of endocrine disruptors prevalent in food contact materials. Objectives: Investigate associations between ultra-processed food intake and urinary phthalates during ...
Brennan H. Baker +12 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Climate emergency and the food system: the impact of May floods on the community food environment of the Rio Grande do Sul State, Brazil [PDF]
: The objective of this study was to describe the impact of the May 2024 floods on the community food environment of Rio Grande do Sul State, Brasil. This is an ecological study in the 92 municipalities of Rio Grande do Sul State that had at least one ...
Lauren Yurgel da Silva +4 more
doaj +1 more source
Effectiveness of a minimally processed food-based nutritional counselling intervention on weight gain in overweight pregnant women: a randomized controlled trial. [PDF]
Sartorelli DS +11 more
europepmc +1 more source

