MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer [PDF]
[Background] MSR1 repeats are a 36–38 bp minisatellite element that have recently been implicated in the regulation of gene expression, through copy number variation (CNV).[Patients and methods] Bioinformatic and experimental methods were used to assess ...
Batra +24 more
core +3 more sources
Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis [PDF]
The genetic system on Trypanosoma brucei has been analysed by generating large numbers of independent progeny clones from two crosses, one between two cloned isolates of Trypanosoma brucei brucei and one between cloned isolates of T. b.
Annette MacLeod +44 more
core +1 more source
Male-mediated developmental toxicity
Male-mediated developmental toxicity has been of concern for many years. The public became aware of male-mediated developmental toxicity in the early 1990s when it was reported that men working at Sellafield might be causing leukemia in their children ...
Diana Anderson +2 more
doaj +1 more source
Discriminatory ability of hypervariable variable number tandem repeat loci in population-based analysis of Mycobacterium tuberculosis strains, London, UK [PDF]
To address conflicting results about the stability of variable number tandem repeat (VNTR) loci and their value in prospective molecular epidemiology of Mycobacterium tuberculosis, we conducted a large prospective population-based analysis of all M ...
Brown, T +3 more
core +3 more sources
Avoiding Ambiguity and Assessing Uniqueness in Minisatellite Alignment [PDF]
Several algorithms have been suggested for minisatellite alignment. Their time complexity is high -- close to O(n^3) -- due to the necessary reconstruction of duplication histories.
, Giegerich, Robert
core +1 more source
A Geographically-Restricted but Prevalent Mycobacterium tuberculosis Strain Identified in the West Midlands Region of the UK between 1995 and 2008 [PDF]
Background: We describe the identification of, and risk factors for, the single most prevalent Mycobacterium tuberculosis strain in the West Midlands region of the UK.Methodology/Principal Findings: Prospective 15-locus MIRU-VNTR genotyping of all M ...
A Fok +42 more
core +13 more sources
Multiple Locus Variable number of tandem repeat Analysis : a molecular genotyping tool for Paenibacillus larvae [PDF]
American Foulbrood, caused by Paenibacillus larvae, is the most severe bacterial disease of honey bees (Apis mellifera). To perform genotyping of P.larvae in an epidemiological context, there is a need of a fast and cheap method with a high resolution ...
Alippi +40 more
core +2 more sources
MNS16A, a functional polymorphic tandem repeat minisatellite, is located in the promoter region of an antisense transcript of the human telomerase reverse transcriptase gene. MNS16A promoter activity depends on the variable number of tandem repeats (VNTR) presenting varying numbers of transcription factor binding sites for GATA binding protein 1 ...
Philipp Hofer +9 more
openalex +4 more sources
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Background Coxiella burnetii, the causative agent of Q fever, has a wide host range. Few epidemiological tools are available, and they are often expensive or not easily standardized across laboratories. In this work, C.
Meyer Hermann +9 more
doaj +1 more source

