Results 11 to 20 of about 367,958 (234)

miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages [PDF]

Frontiers in Immunology
IntroductionMacrophages play fundamental roles in immune regulation and tissue homeostasis, serving as one of the primary cell types that orchestrate tissue repair after injury.
Carmen Alexandra Neculachi, Evelyn-Gabriela Nastase-Rusu, Laudy Cherry, Catalina Iolanda Marinescu-Colan, Spyros Tastsoglou, Bogdan Paul Cosman, Alina Madalina Popa, Cristina Panciuc, Germana Zaccagnini, Germana Zaccagnini, Sergiu Bogdan Catrina, Sergiu Bogdan Catrina, Maya Simionescu, Fabio Martelli, Fabio Martelli, Mihai Bogdan Preda, Alexandrina Burlacu   +16 more
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ROD1 is a seedless target gene of hypoxia-induced miR-210. [PDF]

PLoS ONE, 2012
Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on miRNA nucleotides 2-7.
Pasquale Fasanaro, Sveva Romani, Christine Voellenkle, Biagina Maimone, Maurizio C Capogrossi, Fabio Martelli   +5 more
doaj   +1 more source

Extracellular vesicle expansion of PMIS‐miR‐210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism

Clinical and Translational Medicine, 2022
Background Colorectal cancer (CRC) has a high mortality rate, and therapeutic approaches to treat these cancers are varied and depend on the metabolic state of the tumour.
Steven Eliason, Liu Hong, Yan Sweat, Camille Chalkley, Huojun Cao, Qi Liu, Hank Qi, Hongwei Xu, Fenghuang Zhan, Brad A. Amendt   +9 more
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Changes and Response Predictive Values of Serum miR-210 and miR-181a in Stable Chronic Obstructive Pulmonary Disease Patients Treated with Glucocorticoid Therapy [PDF]

Zhongguo quanke yixue, 2022
Background There are rare studies assessing the efficacy of inhaled glucocorticoids (ICS) , the common therapy for chronic obstructive pulmonary disease (COPD) .
Ke QIN, Tonglin LI, Shuai GONG, Meifang JIANG
doaj   +1 more source

Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. [PDF]

PLoS ONE, 2014
MicroRNA-210 (miR-210), the master hypoxamir, plays pleiotropic roles in certain cancers; however, its role in the development of human colorectal cancer remains unclear.
Ailin Qu, Lutao Du, Yongmei Yang, Hui Liu, Juan Li, Lili Wang, Yimin Liu, Zhaogang Dong, Xin Zhang, Xiumei Jiang, Haiyan Wang, Zewu Li, Guixi Zheng, Chuanxin Wang   +13 more
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miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner

Biomedicines, 2021
Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic stress.
Gurdeep Marwarha, Øystein Røsand, Nathan Scrimgeour, Katrine Hordnes Slagsvold, Morten Andre Høydal   +4 more
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MicroRNA‐210 targets FBXO31 to inhibit tumor progression and regulates the Wnt/β‐catenin signaling pathway and EMT in esophageal squamous cell carcinoma

Thoracic Cancer, 2021
Evidence from previous studies showed that the dysregulation of microRNA (miR) is frequently associated with tumor progression. The aberrant miR‐210 expression has been identified in a variety of tumors.
Jing Meng, Chao Zhang, Tongquan Zhao, Guangwen Shi, Jingjing Zhao, Zhaoxia Lin   +5 more
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miR-210-3p promotes obesity-induced adipose tissue inflammation and insulin resistance by targeting SOCS1 mediated NF-κB pathway

, 2022
Under the condition of chronic obesity, an increased level of free fatty acids along with low oxygen tension in the adipose tissue creates a pathophysiological adipose tissue microenvironment (ATenv) leading to the impairment of adipocyte function and ...
Leena Arora (12966122), Durba Pal (126891), Shaheen Wasil Kabeer (14196548), Debarun Patra (14196545), Archana Sinha (7207964), Aditya Kumar (2629198), Satpal Singh (320396), Soumyajit Roy (1375005), Suman Dasgupta (126894), Upalabdha Dey (14196551), Dipanjan Banerjee (1445326), Kulbhusan Tikoo (14196553)   +11 more
core   +1 more source

Determination of miR-210-5p expression during HIV-1 infection.

, 2021
(A) Heatmap of the relative miRNA expression in mock-inoculated MT4 cells (group 1) or MT4 cells inoculated with pseudotyped HIV-1-GFP (group 2). Arrow indicates miR-210.
Lixia Huang (429197), Jialu Qiao (10004578), Feng Qian (73252), Lingyan Feng (1835029), Qiang You (511068), Binlian Sun (611834), Qian Peng (74762), Song Hu (327019), Xiji Shu (10507889), Wei Liu (20030)   +9 more
core   +1 more source

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

Cell Death and Disease, 2021
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that miR ...
Zaccagnini Germana, Greco Simona, Longo Marialucia, Maimone Biagina, Voellenkle Christine, Fuschi Paola, Carrara Matteo, Creo Pasquale, Maselli Davide, Tirone Mario, Mazzone Massimiliano, Gaetano Carlo, Spinetti Gaia, Martelli Fabio   +13 more
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