Results 61 to 70 of about 15,193 (187)

Plasma micrornas as a biomarker for detection of colorectal cancer in Hospital Universiti Sains Malaysia [PDF]

, 2023
Colorectal cancer (CRC) is one of the cancer with a low survival rate and usually end with death. Colonoscopy is currently the gold standard in detecting CRC disease. However, due to the inconvenience of the procedure, it becomes less appealing. Since
Mohamed, Syarah Syamimi
core  

MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential. [PDF]

, 2019
Lung cancer remains the most lethal cancer among men and women in the United States and worldwide. The majority of lung cancer cases are classified as non-small cell lung cancer (NSCLC). Developing new therapeutics on the basis of better understanding of
Petrek, Hannah, Yu, Ai-Ming
core   +1 more source

Dual‐Atom Dopants Activated Ruthenium Single‐Atom Alloy Boosting Hydrogen Evolution Electrocatalysis in Proton Exchange Membrane Water Electrolyzer

Advanced Functional Materials, EarlyView.
Ni1‐Bi1 dual‐atom dopants are achieved for activating Ru lattices without blocking noble atoms. This model exhibits an ultralow overpotential of 11.4 mV and superb stability at 10 mA cm−2 toward hydrogen evolution reaction, enabling a proton exchange membrane water electrolyzer that needs only 2.233 V to reach 3.0 A cm−2 and operates stably at 1.0 A cm−
Shuiping Luo, Zhichao Yang, Xinyi Cai, Peiling Hu, Lei Xie, Junhao Qiu, Wen Chen, Tianou He, Yong Li, Tangting Li, Yuehan Li, Hong Zhu, Fenghao Jiang, Ke Liu, Jinliang Zhu, Shao‐Qing Liu, Xian‐Zhu Fu, Jing‐Li Luo   +17 more
wiley   +1 more source

Comprehensive analysis of blood cells and plasma identifies tissue-specific miRNAs as potential novel circulating biomarkers in cattle [PDF]

, 2018
Background The potential of circulating miRNAs as biomarkers of tissue function, both in health and disease, has been extensively demonstrated in humans.
Ioannidis, Jason, Donadeu, Francesc
core   +8 more sources

Mir-331-3p Inhibits PRRSV-2 Replication and Lung Injury by Targeting PRRSV-2 ORF1b and Porcine TNF-α

Frontiers in Immunology, 2020
Porcine reproductive and respiratory syndrome (PRRS) caused by a single-stranded RNA virus (PRRSV) is a highly infectious respiratory disease and leads to huge economic losses to the swine industry worldwide.
Xiangbin You, Xiangbin You, Xiangbin You, Yilin Qu, Yilin Qu, Yue Zhang, Jingshu Huang, Xiaoxiao Gao, Xiaoxiao Gao, Chengyu Huang, Chengyu Huang, Gan Luo, Gan Luo, Gan Luo, Qian Liu, Qian Liu, Qian Liu, Min Liu, Min Liu, Dequan Xu, Dequan Xu, Dequan Xu   +21 more
doaj   +1 more source

Electrocatalytic Reduction of CO2 to Ethylene: Catalyst Design and Synchrotron‐Based Characterizations

Advanced Functional Materials, EarlyView.
This review evaluates strategies for electrochemical CO2 reduction to ethylene, focusing on copper‐based catalyst design and microenvironment modulation to achieve industrial‐grade performance. By leveraging operando synchrotron‐based characterizations, we provide a multiscale understanding of dynamic structural transformations and key reaction ...
Meng Zhang, Zuolong Chen, Yimin A. Wu
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Integrative computational mRNA-miRNA interaction analyses of the autoimmune-deregulated miRNAs and well-known Th17 differentiation regulators: An attempt to discover new potential miRNAs involved in Th17 differentiation [PDF]

, 2015
Th17 cells are a lineage of CD4(+) T helper cells in immune system which differentiate from naive CD4(+) T cells and have demonstrated to play a critical role in the pathogenesis of different autoimmune disorders.
Ahmadinejad, Fereshteh., Ghaedi, Kamran., Honardoost, Mohammad Amin., Hosseini, Aref., Naghavian, Reza.   +4 more
core   +2 more sources

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer [PDF]

, 2022
Although microRNAs (miRNAs) contribute to all hallmarks of cancer, miRNA dysregulation in metastasis remains poorly understood. The aim of this work was to reliably identify miRNAs associated with metastatic progression of colorectal cancer (CRC ...
Abrahamsen, Torveig Weum, Böttger, Paul H.M., Dagenborg, Vegar Johansen, Domanska, Diana, Edwin, Bjørn von Gohren, Flatmark, Kjersti, Fretland, Åsmund Avdem, Fromm, Bastian, Hovig, Eivind, Høye, Eirik, Kristensen, Annette Torgunrud, Lorenz, Susanne, Lund-Andersen, Christin   +12 more
core   +1 more source