Results 31 to 40 of about 482,752 (300)
miR‐210: The Master Hypoxamir [PDF]
Microcirculation, 2012 Please cite this paper as: Chan YC, Banerjee J, Choi SY, Sen CK. miR‐210: The master hypoxamir. Microcirculation19: 215–223, 2012.AbstractMicroRNAs are small non‐coding RNAs implicated mainly in post‐transcriptional gene silencing by interacting with the untranslated region of the transcript.
Yuk C, Chan +3 more
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Changes and Response Predictive Values of Serum miR-210 and miR-181a in Stable Chronic Obstructive Pulmonary Disease Patients Treated with Glucocorticoid Therapy [PDF]
Zhongguo quanke yixue, 2022 Background There are rare studies assessing the efficacy of inhaled glucocorticoids (ICS) , the common therapy for chronic obstructive pulmonary disease (COPD) .
Ke QIN, Tonglin LI, Shuai GONG, Meifang JIANG
doaj +1 more source
Stem Cell Reviews and Reports, 2023 Mesenchymal stem cell-derived extracellular vesicles (MSCs-EVs) possess cardioprotection in acute myocardial infarction. Nevertheless, the therapeutic intervention potential and the molecular mechanism of EVs from NMN (Nicotinamide mononucleotide ...
Yanan Pu +10 more
semanticscholar +1 more source
MiR-210 – micromanager of the hypoxia pathway [PDF]
Trends in Molecular Medicine, 2010 Hypoxia inducible factors (HIFs) regulate a variety of genes to prepare cells to adapt and survive under a hypoxic environment. Recently, microRNAs (miRNAs) have emerged as a new class of genes regulated by HIFs in response to hypoxia, of which miR-210 is the most consistently and predominantly upregulated miRNA.
Xin, Huang +2 more
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Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. [PDF]
PLoS ONE, 2014 MicroRNA-210 (miR-210), the master hypoxamir, plays pleiotropic roles in certain cancers; however, its role in the development of human colorectal cancer remains unclear.
Ailin Qu +13 more
doaj +1 more source
Biomedicines, 2021 Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic stress.
Gurdeep Marwarha +4 more
doaj +1 more source
MIR-210 modulates mitochondrial respiration in placenta with preeclampsia [PDF]
Placenta, 2012 Preeclampsia (PE) affects 5-8% of all pregnancies and is associated with significant maternal and fetal morbidity and mortality. Placental mitochondrial dysfunction has been reported in PE. MicroRNAs (miRNA) are small non-coding RNAs that regulate gene expression through mRNA degradation and translational repression.
S, Muralimanoharan +5 more
openaire +2 more sources
Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation [PDF]
, 2021 Unbalanced immune responses to pathogens can be life-threatening although the underlying regulatory mechanisms remain unknown. Here, we show a hypoxia-inducible factor 1α-dependent microRNA (miR)-210 up-regulation in monocytes and macrophages upon ...
Cappellesso F. +27 more
core +8 more sources
Multiple functions of hypoxia-regulated miR-210 in cancer [PDF]
Journal of Experimental & Clinical Cancer Research, 2014 MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally. miRNAs can be induced by a variety of stresses such as hypoxia, and are involved in diverse biological processes including differentiation, cell proliferation, cell death, and tumorigenesis. Hypoxia, a common feature of tumor microenvironment, can induce a
Qin, Qin, Furong, Wei, Baosheng, Li
openaire +2 more sources
Environmental science and pollution research international, 2023 Kidney injury represents a global concern, leading to chronic kidney disease. The organophosphate insecticide malathion (MT) demonstrates environmental disturbance and impairment of different mammalian organs, including kidneys.
A. Ismail, A. Salem, M. Eassawy
semanticscholar +1 more source