Results 11 to 20 of about 37,458 (290)

ROD1 is a seedless target gene of hypoxia-induced miR-210. [PDF]

PLoS ONE, 2012
Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on miRNA nucleotides 2-7.
Pasquale Fasanaro, Sveva Romani, Christine Voellenkle, Biagina Maimone, Maurizio C Capogrossi, Fabio Martelli   +5 more
doaj   +4 more sources

miR-210: fine-tuning the hypoxic response [PDF]

, 2014
Hypoxia is a central component of the tumor microenvironment and represents a major source of therapeutic failure in cancer therapy. Recent work has provided a wealth of evidence that noncoding RNAs and, in particular, microRNAs, are significant members ...
A Allegra, A Giannakakis, A Hüttenhofer, A Krek, A Shinohara, A Ventura, A Zhao, AC Koong, AE Pasquinelli, AM Cheng, AS Ho, B Malzkorn, B Wightman, BE Baysal, BJ Reinhart, BL Pineles, BP Lewis, BP Lewis, C Camps, C Devlin, C Nakada, C-C Chio, CH Lawrie, D Baek, D Betel, D Gou, D Hanahan, D Juan, DA Enquobahrie, DA Landau, DD Taylor, DP Bartel, DP Bartel, DS Schwarz, E Balsa, E Bostjancic, E Fabbri, E Fabbri, E Favaro, E Gottlieb, E Miko, E Rooij van, EJ Jung, F Mochel, F Rothe, F Wu, FE Benson, FV Karginov, G Leone, G Meroni, G Wan, GA Calin, GL Semenza, GL Semenza, GL Semenza, GL Semenza, GL Wang, GL Wang, GL Wang, H Antonicka, H Guo, H Iguchi, H Valadi, H Zhang, H-Y Chen, HE Gee, HW Kim, HW Kim, HW King, I Satzger, J Brugarolas, J He, J Lu, J Sarkar, J Stenvang, J Tabernero, J Wang, JA Foekens, JA Lees, JA Weber, JC Presti Jr, JC Venter, JD Gordan, JM Brown, JR Gnarra, JW Kim, K Jeyaseelan, K Pulkkinen, K Ruan, KP Porkka, L Cicchillitti, L Hong, L Qin, L Salmena, LP Lim, M Ivan, M Kertesz, M Liu, M Maragkakis, M Raponi, M Redova, M Selbach, MA Alaiti, MA Cortez, MA Valencia-Sanchez, ME Crosby, MP Murphy, MP Puissegur, MV Iorio, MV Iorio, MZ Michael, N Bushati, N Yanaihara, NC Denko, NC Denko, NL Simone, NMA White, O Bunoust, P Fasanaro, P Fasanaro, P Fasanaro, P Jaakkola, P Vaupel, PJ Hurlin, PS Mitchell, R Bindra, R Faraonio, R Gambari, R Garzon, R Kulshreshtha, R Kulshreshtha, RA Gatenby, RB Donker, RC Lee, RD Guzy, RE Lanford, RF Place, RK Mutharasan, S Biswas, S Djebali, S Djuranovic, S Djuranovic, S Gilad, S Greco, S Griffiths-Jones, S Hammer, S Hu, S Krick, S Kuijper, S Tsuchiya, S Vasudevan, S Wang, SA Ciafre, SY Chan, T Greither, T Greither, T Kawamata, T Li, T Thum, T Toyama, TJ Kelly, W Yang, W Zundel, WH Tong, WR Wilson, X Chen, X Huang, X Huang, X Zhang, XM Zhu, Y Lee, Y Lee, Y Liu, Y Liu, Y Mizuno, Y Murakami, Y Nakamura, Y Nie, YL Lou, Z Chen, Z Zhang   +180 more
core   +4 more sources

miR-210: More than a silent player in hypoxi [PDF]

IUBMB Life, 2011
Multiple studies have consistently established that miR (microRNA)-210 induction is a feature of the hypoxic response in both normal and transformed cells.
Devlin, Cecilia, Greco, Simona, Ivan, Mircea, Martelli, Fabio   +3 more
core   +4 more sources

Roles of miR-210 in the pathogenesis of pre-eclampsia

Archives of Medical Science, 2018
Introduction This study aimed to explore the bio-function of miR-210 in the pathogenesis of pre-eclampsia and provide new insights into the diagnosis and treatment of pre-eclampsia.
Jiyun Li, Guimei Wu, Yanmin Cao, Zhi Hou
doaj   +3 more sources

miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages [PDF]

Frontiers in Immunology
IntroductionMacrophages play fundamental roles in immune regulation and tissue homeostasis, serving as one of the primary cell types that orchestrate tissue repair after injury.
Carmen Alexandra Neculachi, Evelyn-Gabriela Nastase-Rusu, Laudy Cherry, Catalina Iolanda Marinescu-Colan, Spyros Tastsoglou, Bogdan Paul Cosman, Alina Madalina Popa, Cristina Panciuc, Germana Zaccagnini, Germana Zaccagnini, Sergiu Bogdan Catrina, Sergiu Bogdan Catrina, Maya Simionescu, Fabio Martelli, Fabio Martelli, Mihai Bogdan Preda, Alexandrina Burlacu   +16 more
doaj   +2 more sources

Involvement of upregulation of miR-210 in a rat epilepsy model

Neuropsychiatric Disease and Treatment, 2016
Licheng Chen, Hao Zheng, Shimeng Zhang Neurological Department of Internal Medicine, Linyi People’s Hospital of Shandong Province, Linyi, People’s Republic of China Abstract: Epilepsy is a common type of neurological disorder with ...
Chen L, Zheng H, Zhang S
doaj   +4 more sources

Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer. [PDF]

Curr Issues Mol Biol, 2023
Pancreatic cancer (PC) poses significant clinical challenges, with late-stage diagnosis and limited therapeutic options contributing to its dismal prognosis. A hallmark feature of PC is the presence of a profoundly hypoxic tumour microenvironment, resulting from various factors such as fibrotic stroma, rapid tumour cell proliferation, and poor ...
Lian M, Mortoglou M, Uysal-Onganer P.
europepmc   +4 more sources

Elevation of circulating miR-210-3p in high-altitude hypoxic environment [PDF]

Frontiers in Physiology, 2016
Background: The induction of miR-210-3p, a master hypoxamir, is a consistent feature of the hypoxic response in both normal and malignant cells. However, whether miR-210-3p acts as a circulating factor in response to a hypoxic environment remains unknown.
Yan eYan, Yan eYan, Cheng eWang, Cheng eWang, Wanqing eZhou, Yonghui eShi, Pengtao eGuo, Yuxiu eLiu, Junjun eWang, Chen-Yu eZhang, Chunni eZhang   +10 more
doaj   +3 more sources

MiR-210 – micromanager of the hypoxia pathway [PDF]

Trends in Molecular Medicine, 2010
Hypoxia inducible factors (HIFs) regulate a variety of genes to prepare cells to adapt and survive under a hypoxic environment. Recently, microRNAs (miRNAs) have emerged as a new class of genes regulated by HIFs in response to hypoxia, of which miR-210 is the most consistently and predominantly upregulated miRNA.
Xin, Huang, Quynh-Thu, Le, Amato J, Giaccia   +2 more
openaire   +2 more sources

Extracellular vesicle expansion of PMIS‐miR‐210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism

Clinical and Translational Medicine, 2022
Background Colorectal cancer (CRC) has a high mortality rate, and therapeutic approaches to treat these cancers are varied and depend on the metabolic state of the tumour.
Steven Eliason, Liu Hong, Yan Sweat, Camille Chalkley, Huojun Cao, Qi Liu, Hank Qi, Hongwei Xu, Fenghuang Zhan, Brad A. Amendt   +9 more
doaj   +1 more source