Results 31 to 40 of about 37,458 (290)

miR-210 is essential to retinal homeostasis in fruit flies and mice. [PDF]

Biol Direct
Abstract Background miR-210 is one of the most evolutionarily conserved microRNAs. It is known to be involved in several physiological and pathological processes, including response to hypoxia, angiogenesis, cardiovascular diseases and cancer.
Colaianni D, Virga F, Tisi A, Stefanelli C, Zaccagnini G, Cusumano P, Sales G, Preda MB, Martelli F, Taverna D, Mazzone M, Bertolucci C, Maccarone R, De Pittà C.   +13 more
europepmc   +8 more sources

MIR-210 modulates mitochondrial respiration in placenta with preeclampsia [PDF]

Placenta, 2012
Preeclampsia (PE) affects 5-8% of all pregnancies and is associated with significant maternal and fetal morbidity and mortality. Placental mitochondrial dysfunction has been reported in PE. MicroRNAs (miRNA) are small non-coding RNAs that regulate gene expression through mRNA degradation and translational repression.
S, Muralimanoharan, A, Maloyan, J, Mele, C, Guo, L G, Myatt, L, Myatt   +5 more
openaire   +2 more sources

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

Cell Death and Disease, 2021
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that miR ...
Zaccagnini Germana, Greco Simona, Longo Marialucia, Maimone Biagina, Voellenkle Christine, Fuschi Paola, Carrara Matteo, Creo Pasquale, Maselli Davide, Tirone Mario, Mazzone Massimiliano, Gaetano Carlo, Spinetti Gaia, Martelli Fabio   +13 more
doaj   +1 more source

Analysis of differential expression of hypoxia-inducible microRNA-210 gene targets in mild and severe preeclamptic patients

Non-coding RNA Research, 2021
Preeclampsia (PE) is a multi-system disorder that is specific to human pregnancy. Inadequate oxygenation of uterus and placenta is considered as one of the leading causes for the disease.
Deeba S. Jairajpuri, Zainab H. Malalla, Sameh Sarray, Naeema Mahmood   +3 more
doaj   +1 more source

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells [PDF]

, 2014
PLC-beta 1 (PLCβ1) inhibits in human K562 cells erythroid differentiation induced by mithramycin (MTH) by targeting miR-210 expression. Inhibition of miR-210 affects the erythroid differentiation pathway and it occurs to a greater extent in MTH-treated ...
Bavelloni, Alberto, Blalock, William, Cocco, Lucio, Faenza, Irene, Fiume, Roberta, Matteucci, Alessandro, McCubrey, James A., NC DOCKS at East Carolina University, Poli, Alessandro, Ramazzotti, Giulia   +9 more
core   +2 more sources

Multiple functions of hypoxia-regulated miR-210 in cancer [PDF]

Journal of Experimental & Clinical Cancer Research, 2014
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally. miRNAs can be induced by a variety of stresses such as hypoxia, and are involved in diverse biological processes including differentiation, cell proliferation, cell death, and tumorigenesis. Hypoxia, a common feature of tumor microenvironment, can induce a
Qin, Qin, Furong, Wei, Baosheng, Li
openaire   +2 more sources

Inhibition of microRNA-210 provides neuroprotection in hypoxic–ischemic brain injury in neonatal rats

Neurobiology of Disease, 2016
Perinatal hypoxic–ischemic encephalopathy (HIE) is associated with high neonatal mortality and severe long-term neurologic morbidity. Yet the mechanisms of brain injury in infants with HIE remain largely elusive.
Qingyi Ma, Chiranjib Dasgupta, Yong Li, Nikita M. Bajwa, Fuxia Xiong, Benjamin Harding, Richard Hartman, Lubo Zhang   +7 more
doaj   +1 more source

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma [PDF]

, 2017
The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Carbone, Antonio, Costantini, Manuela, DI CARLO, Angelina, Fazi, Francesco, Gallucci, Michele, Marigliano, Chiara, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Ricci, Serena, Simone, Giuseppe, Tito, Claudia   +12 more
core   +2 more sources

Dysregulation of miR-210 is involved in the development of diabetic retinopathy and serves a regulatory role in retinal vascular endothelial cell proliferation

European Journal of Medical Research, 2020
Background Diabetic retinopathy is a common complication of diabetes mellitus (DM). The purpose of this study was to investigate the expression and clinical significance of miR-210 in DR patients and explore the regulatory effect of miR-210 on vascular ...
Chengyu Yin, Xiangqiang Lin, Yafei Sun, Xinli Ji   +3 more
doaj   +1 more source

mir-210: A Sensor for Hypoxic Stress during Tumorigenesis [PDF]

Molecular Cell, 2009
In this issue of Molecular Cell, Huang et al. (2009) demonstrate that hypoxia-inducible mir-210 acts as a rheostat for cellular adaptation and survival by inhibiting tumor initiation.
Mathew, Lijoy K., Simon, M. Celeste
openaire   +2 more sources