Results 21 to 30 of about 367,978 (251)

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

Cell Death and Disease, 2021
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that miR ...
Zaccagnini Germana, Greco Simona, Longo Marialucia, Maimone Biagina, Voellenkle Christine, Fuschi Paola, Carrara Matteo, Creo Pasquale, Maselli Davide, Tirone Mario, Mazzone Massimiliano, Gaetano Carlo, Spinetti Gaia, Martelli Fabio   +13 more
doaj   +1 more source

Long Non-coding RNA DLEU2L Targets miR-210-3p to Suppress Gemcitabine Resistance in Pancreatic Cancer Cells via BRCA2 Regulation

Frontiers in Molecular Biosciences, 2021
Gemcitabine (GEM) resistance remains a challenging clinical issue to overcome in chemotherapy against pancreatic cancer. We previously demonstrated that miR-210 derived from pancreatic cancer stem cells enhanced the GEM-resistant properties of pancreatic
Fei Xu, Heshui Wu, Jiongxin Xiong, Tao Peng   +3 more
doaj   +1 more source

TGIF2 expression in miR-210-5p-overexpressing cells.

, 2021
(A) Predicted miR-210-5p binding sites in the TGIF2-3`UTR. (B) HOS cells were transfected with the luciferase reporter vector of TGIF2-3`UTR (upper image) and various amounts of miR-210-5p mimic, and dual-luciferase activity was measured 30 h later. (C-D)
Lixia Huang (429197), Jialu Qiao (10004578), Feng Qian (73252), Lingyan Feng (1835029), Qiang You (511068), Binlian Sun (611834), Qian Peng (74762), Song Hu (327019), Xiji Shu (10507889), Wei Liu (20030)   +9 more
core   +1 more source

Inhibition of microRNA-210 provides neuroprotection in hypoxic–ischemic brain injury in neonatal rats

Neurobiology of Disease, 2016
Perinatal hypoxic–ischemic encephalopathy (HIE) is associated with high neonatal mortality and severe long-term neurologic morbidity. Yet the mechanisms of brain injury in infants with HIE remain largely elusive.
Qingyi Ma, Chiranjib Dasgupta, Yong Li, Nikita M. Bajwa, Fuxia Xiong, Benjamin Harding, Richard Hartman, Lubo Zhang   +7 more
doaj   +1 more source

The effect of HIV-1 proteins to the miR-210-5p promoter.

, 2021
HOS cells were co-transfected with miR-210-full-promoter-luciferase reporter plasmid (miPPR-210 2.3K) or miR-210-core-promoter-luciferase reporter plasmid (miPPR-210 894bp) and the plasmids encoding each of 10 HIV-1 proteins, as indicated, for 30h.
Lixia Huang (429197), Jialu Qiao (10004578), Feng Qian (73252), Lingyan Feng (1835029), Qiang You (511068), Binlian Sun (611834), Qian Peng (74762), Song Hu (327019), Xiji Shu (10507889), Wei Liu (20030)   +9 more
core   +1 more source

Transglutaminase-Polyethyleneimine Nanoflowers Mediated Cellular Delivery of Anti-miR-210 for Effective Glioblastoma Therapy

, 2023
Glioblastoma (GBM) is a deadly tumor of the central nervous system (CNS) having a dismal prognosis. miRNA-based therapeutics hold immense potential for GBM therapy; however, its delivery remains a daunting challenge.
Sagar Sengupta (1910200), Indranil Mondal (1534171), Sagar Sengupta, Syeda Warisul Fatima (15305268), Swati Priya, Ritu Kulshreshtha, Sunil Kumar Khare (15305271), Swati Priya (10225148), Syeda Warisul Fatima, Indranil Mondal, Sunil Kumar Khare, Ritu Kulshreshtha (488574)   +11 more
core   +1 more source

Dysregulation of miR-210 is involved in the development of diabetic retinopathy and serves a regulatory role in retinal vascular endothelial cell proliferation

European Journal of Medical Research, 2020
Background Diabetic retinopathy is a common complication of diabetes mellitus (DM). The purpose of this study was to investigate the expression and clinical significance of miR-210 in DR patients and explore the regulatory effect of miR-210 on vascular ...
Chengyu Yin, Xiangqiang Lin, Yafei Sun, Xinli Ji   +3 more
doaj   +1 more source

Analysis of differential expression of hypoxia-inducible microRNA-210 gene targets in mild and severe preeclamptic patients

Non-coding RNA Research, 2021
Preeclampsia (PE) is a multi-system disorder that is specific to human pregnancy. Inadequate oxygenation of uterus and placenta is considered as one of the leading causes for the disease.
Deeba S. Jairajpuri, Zainab H. Malalla, Sameh Sarray, Naeema Mahmood   +3 more
doaj   +1 more source

The effect of miR-210-5p inhibitor to TGIF2.

, 2021
(A) HOS cells were transfected with the Flag-TGIF2-3`UTR and various amounts of miR-210-5p inhibitor, and Flag-TGIF2-3`UTR was measured. (B) MT4 cells were transfected with various amounts of miR-210-5p inhibitor, and TGIF2 was measured.
Lixia Huang (429197), Jialu Qiao (10004578), Feng Qian (73252), Lingyan Feng (1835029), Qiang You (511068), Binlian Sun (611834), Qian Peng (74762), Song Hu (327019), Xiji Shu (10507889), Wei Liu (20030)   +9 more
core   +1 more source

The effect of miR-210-5p mimic NC to TGIF2.

, 2021
(A) HOS cells were transfected with the luciferase reporter vector of TGIF2-3`UTR and various amounts of miR-210-5p mimic NC, and dual-luciferase activity was measured 30 h later. (B) MT4 cells were transfected with various amounts of miR-210-5p mimic NC,
Lixia Huang (429197), Jialu Qiao (10004578), Feng Qian (73252), Lingyan Feng (1835029), Qiang You (511068), Binlian Sun (611834), Qian Peng (74762), Song Hu (327019), Xiji Shu (10507889), Wei Liu (20030)   +9 more
core   +1 more source