Results 41 to 50 of about 482,752 (300)
Thoracic Cancer, 2021 Evidence from previous studies showed that the dysregulation of microRNA (miR) is frequently associated with tumor progression. The aberrant miR‐210 expression has been identified in a variety of tumors.
Jing Meng +5 more
doaj +1 more source
Diagnostic Value of Plasma miR-181b, miR-196a, and miR-210 Combination in Pancreatic Cancer
Gastroenterology Research and Practice, 2020 Purpose. This study was aimed at investigating the roles of plasma miR-181b, miR-196a, and miR-210 in the diagnosis of pancreatic cancer (PC). Methods. Plasma samples were isolated from 40 patients with PC and 40 healthy individuals, respectively.
Gongpan Liu +5 more
doaj +1 more source
MicroRNA-210 regulates dendritic morphology and behavioural flexibility in mice [PDF]
, 2023 MicroRNAs are known to be critical regulators of neuronal plasticity. The highly-conserved, hypoxia- regulated microRNA-210 (miR-210) has been shown to be associated with long term memory in invertebrates and dysregulated in neurodevelopmental and ...
Claudianos, Charles +4 more
core +1 more source
Translational Pediatrics, 2023 Background Insulin resistance has been implicated in the pathogenesis of children born small for gestational age (SGA) with catch-up growth (CUG). Adipose tissue macrophages (ATMs) regulate insulin resistance by secreting exosomes containing microRNA ...
Hui Xiong +7 more
semanticscholar +1 more source
miR‐210 promotes osteoblastic differentiation through inhibition of AcvR1b [PDF]
FEBS Letters, 2009 Although microRNAs (miRNAs) are involved in many biological processes, the mechanisms whereby miRNAs regulate osteoblastic differentiation are poorly understood. Here, we found that BMP‐4‐induced osteoblastic differentiation of bone marrow‐derived ST2 stromal cells was promoted and repressed after transfection of sense and antisense miR‐210 ...
Mizuno, Yosuke +11 more
openaire +2 more sources
mir-210: A Sensor for Hypoxic Stress during Tumorigenesis [PDF]
Molecular Cell, 2009 In this issue of Molecular Cell, Huang et al. (2009) demonstrate that hypoxia-inducible mir-210 acts as a rheostat for cellular adaptation and survival by inhibiting tumor initiation.
Mathew, Lijoy K., Simon, M. Celeste
openaire +2 more sources
Frontiers in Molecular Biosciences, 2021 Gemcitabine (GEM) resistance remains a challenging clinical issue to overcome in chemotherapy against pancreatic cancer. We previously demonstrated that miR-210 derived from pancreatic cancer stem cells enhanced the GEM-resistant properties of pancreatic
Fei Xu +3 more
doaj +1 more source
Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma [PDF]
, 2017 The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Carbone, Antonio +12 more
core +2 more sources
Hypoxia induces microRNA miR‐210 in vitro and in vivo [PDF]
FEBS Letters, 2008 Shortage of oxygen is one of the prime stress conditions in tissues. In this study, we looked for microRNAs expressed during hypoxia and showed that miR‐210 expression was upregulated in response to hypoxia in vitro and in vivo. An active form of the HIF‐1α induced the expression of miR‐210, showing the involvement of the HIF‐1 signaling pathway in miR‐
Pulkkinen, Kati +4 more
openaire +2 more sources
Neurobiology of Disease, 2016 Perinatal hypoxic–ischemic encephalopathy (HIE) is associated with high neonatal mortality and severe long-term neurologic morbidity. Yet the mechanisms of brain injury in infants with HIE remain largely elusive.
Qingyi Ma +7 more
doaj +1 more source