Results 91 to 100 of about 274,131 (166)

MiR-130b-3p promotes colorectal cancer progression by targeting CHD9

open access: yes, 2022
Colorectal cancer (CRC) is the third most common cancer worldwide. Previous research revealed that microRNA 130b-3p (miR-130b-3p) significantly upregulated in CRC patients can be detected in feces from patients with such a neoplasm.
Liangliang Zhan (485826)   +4 more
core   +1 more source

Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells

open access: yesTumor Biology, 2017
The mechanism of dsRNA-induced gene activation (RNAa) is being gradually unveiled. The plentiful evidence that it existed in mammalian species other than human demonstrated that dsRNA-mediated RNAa is a conservative phenomenon.
Chuanchang Li   +6 more
doaj   +1 more source

LncRNA BCYRN1/miR-490-3p/POU3F2, served as a ceRNA network, is connected with worse survival rate of hepatocellular carcinoma patients and promotes tumor cell growth and metastasis

open access: yesCancer Cell International, 2020
s Backgrounds LncRNA Brain Cytoplasmic RNA 1 (BCYRN1) has been certified to modulate cancer cells growth and aggressiveness in several tumors. However, research about function of BCYRN1 in hepatocellular carcinoma (HCC) is limited.
Shichao Ding   +4 more
doaj   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi   +4 more
wiley   +1 more source

Circ_0020887 Silencing Combats Hypoxic-Induced Cardiomyocyte Injury in an MiR-370-3p/CYP1B1-Dependent Manner

open access: yesInternational Heart Journal
Targeting circular RNA has been a novel approach to preventing and limiting acute myocardial infarction (AMI). Here, we planned to investigate the role and mechanism of circ_0020887 in AMI progression.Hypoxic injury in human cardiomyocytes (AC16) was measured using cell counting kit-8 assay, 5-ethynyl-2'-deoxyuridine assay, flow cytometry, and ...
Chen, Huiqin   +6 more
openaire   +2 more sources

Metal–Organic Frameworks as Programable Platforms for Micro‐ and Optoelectronics: From Dielectrics to Semiconductors and White‐Light Emitters

open access: yesSmall Science, Volume 6, Issue 6, June 2026.
Programable metal–organic framework (MOF) architectures are revealed as versatile micro‐ and optoelectronic platforms, spanning low/high‐κ dielectrics, semiconductive frameworks, and electrically driven phosphor‐free white emitters. Metal nodes, π‐conjugated linkers, guests, and confined water emerge as decisive handles for tuning charge transport ...
Pounraj Thanasekaran   +5 more
wiley   +1 more source

Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint

open access: yesAdvances in Cancer Biology - Metastasis
As an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad   +6 more
doaj   +1 more source

Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis

open access: yesJournal of Biomedical Science, 2020
Background Circular RNAs (circRNAs) represent a class of non-coding RNAs (ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could act as critical regulators in the atherogenesis of cerebrovascular disease.
Shanchao Zhang   +8 more
doaj   +1 more source

Interaction of miRNA-370-3p and the AKT/Foxo1 pathway in trophoblast cells in gestational diabetes mellitus [PDF]

open access: yes, 2022
Background and aims: Gestational diabetes mellitus (GDM) is one of the most common clinical pregnant diseases with. miRNAs participate in a variety of biological functions as well as the pathogenesis of GDM. Previously, our group found by qPCR miR-370-3p
Ji, Jinlu
core  

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