Results 71 to 80 of about 274,131 (166)

LINC01232 Sponges Multiple miRNAs and Its Clinical Significance in Pancreatic Adenocarcinoma Diagnosis and Prognosis

Technology in Cancer Research & Treatment, 2021
Background: Long noncoding RNAs have been demonstrated to play important roles in different kinds of human malignancy. The purpose of this study was to evaluate the diagnostic and prognostic value of long intergenic non-protein coding RNA 1232 (LINC01232)
Wenyan Du MM, Chengbin Lei MM, Yanzhen Wang MM, Yiwen Ding MM, Peng Tian MM   +4 more
doaj   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source

MOESM3 of CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

, 2019
Additional file 3: Figure S2. The seed regions between miR-877-3p and circMYO10. (a) Schematic illustration showing complementarity to the miR-370-3p sequence in circMYO10.
Shengyu Wang (306423), Jianjun Ma (158111), Yute Yang (5463545), Gang Liu (81776), Yizheng Wu (1665766), Panyang Shen (7587599), Junxin Chen (2951379), Xiangqian Fang (6050843), Shuai Chen (506142), Shuying Shen (6050849), Shunwu Fan (4411273), Hongfei Wu (470334), Yifan Fang (7587602), Ziang Xie (3743974)   +13 more
core   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features

World Journal of Surgical Oncology, 2012
Background MicroRNA (miRNA) expression is known to be deregulated in ovarian carcinomas. However, limited data is available about the miRNA expression pattern for the benign or borderline ovarian tumors as well as differential miRNA expression pattern ...
Lee Heejeong, Park Chul, Deftereos Georgios, Morihara Janice, Stern Joshua E, Hawes Stephen E, Swisher Elizabeth, Kiviat Nancy B, Feng Qinghua   +8 more
doaj   +1 more source

Potassium binders and continuation of renin–angiotensin system inhibitors/mineralocorticoid receptor antagonist in chronic kidney disease and heart failure (the DEMONSTRATE database)

Journal of Internal Medicine, Volume 300, Issue 2, Page 179-192, August 2026.
Abstract Introduction Hyperkalaemia is a serious complication in patients with chronic kidney disease (CKD) and heart failure (HF), often leading to the discontinuation of renin–angiotensin–aldosterone system inhibitors (RAASi; renin‐angiotensin system inhibitors [RASi] and mineralocorticoid receptor antagonists [MRAs]) despite their cardiorenal ...
Hans Furuland, Anders Olof Larsson, Milica Uhde, Kristel Parv, Matilda Almstedt, Thomas Cars, Maria K. Svensson   +6 more
wiley   +1 more source

miR-200c-3p regulates a4 integrin-mediated T cell adhesion and migration [PDF]

三重大学博士(医学)application/pdfA microRNA miR-200c-3p is a regulator of epithelial-mesenchymal transition to control adhesion and migration of epithelial and mesenchymal cells.
Mokmued, Khwanchanok
core   +1 more source

miR-144-3p and miR-486a-3p would be delivered to the liver via serum EVs in iFIRKO mice.

, 2023
(A) Increased serum EV-miRNAs validated by quantitative RT-PCR. Data were normalized to the levels of miR-148a-3p, which is a GeNorm algorithm-selected reference gene from the miRNA sequencing data. (B) Mature miRNA levels in the liver. Expression levels
Rei Okazaki (15411769), Masato Horino (14249459), Jun Aoki (2258638), Masanori Murakami (2530054), Kazutaka Tsujimoto (5086124), Tetsuya Yamada (219211), Chikara Komiya (3178998), Kenji Ikeda (500680), Yoshihiro Niitsu (14249456), Kazunari Hara (14249453), Akira Takeuchi (2421142)   +10 more
core   +1 more source

Photoperiods induced the circRNA differential expression in the thyroid gland of OVX+E2 ewes

Frontiers in Endocrinology, 2022
Circular RNAs (circRNAs) are non-coding RNAs newly identified and play important roles in RNA regulation. However, little is known regarding photoperiods induced circRNAs in the thyroid gland.
Wei Wang, Xiaoyun He, Ran Di, Xiangyu Wang, Mingxing Chu   +4 more
doaj   +1 more source

Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma. [PDF]

Mol Cancer, 2020
Abstract Background Circular RNAs (circRNAs) have been reported to have critical regulatory roles in tumor biology. However, their contribution to melanoma remains largely unknown. Methods CircRNAs derived from oncogene CD151 were detected and verified by analyzing a large ...
Wei CY, Zhu MX, Lu NH, Liu JQ, Yang YW, Zhang Y, Shi YD, Feng ZH, Li JX, Qi FZ, Gu JY.   +10 more
europepmc   +5 more sources