Results 51 to 60 of about 274,131 (166)

Data_Sheet_1_Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis.PDF

, 2022
BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Litong Zhu (6578963), Zhuomin Huang (13951260), Quanfu Zhang (158693), Jilong Yao (13951263), Depeng Zhao (1608115)   +4 more
core   +1 more source

CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

Molecular Cancer, 2019
Background CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and is upregulated in osteosarcoma cell lines, but its functional role in osteosarcoma is still unknown.
Junxin Chen, Gang Liu, Yizheng Wu, Jianjun Ma, Hongfei Wu, Ziang Xie, Shuai Chen, Yute Yang, Shengyu Wang, Panyang Shen, Yifan Fang, Shunwu Fan, Shuying Shen, Xiangqian Fang   +13 more
doaj   +1 more source

Wnt7a activates canonical Wnt signaling, promotes bladder cancer cell invasion, and is suppressed by miR-370-3p [PDF]

Journal of Biological Chemistry, 2018
Once urinary bladder cancer (UBC) develops into muscle-invasive bladder cancer, its mortality rate increases dramatically. However, the molecular mechanisms of UBC invasion and metastasis remain largely unknown. Herein, using 5637 UBC cells, we generated two sublines with low (5637 NMI) and high (5637 HMI) invasive capabilities.
Xiaojing, Huang, Hongwen, Zhu, Zemin, Gao, Junzun, Li, Junlong, Zhuang, Yu, Dong, Bing, Shen, Meiqian, Li, Hu, Zhou, Hongqian, Guo, Ruimin, Huang, Jun, Yan   +11 more
openaire   +2 more sources

Prediction of circMARK3-miR-1273g-3p-Fgr interaction.

, 2019
(A) miR-1273g-3p targeting Fgr. (B) miR-1273g-3p targeting circMARK3. (C) Prediction of circMARK3-miRNA-mRNA interaction. The base-pairing and the minimum free energy (mfe) were predicted using the RNA hybrid program. (D-F) The relative expression levels
Yuting Guo (2223820), Xiyu Zhu (3719617), Qing Zhou (52712), Congcong Tian (1650379), Bing Gong (1602628), Dongjin Wang (35909), Rui Zhao (43391), Xinlong Tang (6894287)   +7 more
core   +1 more source

Image_3_Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis.TIF

, 2022
BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Litong Zhu (6578963), Zhuomin Huang (13951260), Quanfu Zhang (158693), Jilong Yao (13951263), Depeng Zhao (1608115)   +4 more
core   +1 more source

Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p

BMC Cancer, 2019
Background Glutamate metabotropic receptors (GRM) play a variety of roles in neuronal cells. However, their clinical significance and biological functions in breast cancer remain unknown. Methods RNA sequencing data of breast cancer was obtained from the
Bin Xiao, Daxiang Chen, Quan Zhou, Jianfeng Hang, Weiyun Zhang, Zhenzhan Kuang, Zhaohui Sun, Linhai Li   +7 more
doaj   +1 more source

MOESM4 of CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

, 2019
Additional file 4: Figure S3. MiR-370-3p showed a strong effect on the migration, invasion, and EMT process than miR-877-3p in MG63 and U2OS cells. (a) MiR-370-3p and miR-877-3p inhibited MG63 and U2OS cells to migrate and invade through transwells ...
Shengyu Wang (306423), Jianjun Ma (158111), Yute Yang (5463545), Gang Liu (81776), Yizheng Wu (1665766), Panyang Shen (7587599), Junxin Chen (2951379), Xiangqian Fang (6050843), Shuai Chen (506142), Shuying Shen (6050849), Shunwu Fan (4411273), Hongfei Wu (470334), Yifan Fang (7587602), Ziang Xie (3743974)   +13 more
core   +1 more source

Identification of Serum miR-501-3p and miR-338-3p as Novel Diagnostic Biomarkers for Breast Cancer and Their Target Genes Associated with Immune Infiltration

, 2023
Liqian Yin,1 Yansheng Ding,2 Yang Wang,3 Chengdong Wang,2 Kuisheng Sun,1 Liquan Wang3 1College of Medical Laboratory Medicine, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2Clinical Laboratory, Weifang People’s Hospital ...
Ding Y, Wang C, Wang Y, Yin L, Sun K, Wang L   +5 more
core  

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

MOESM1 of CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling

, 2019
Additional file 1. Figure S1. (A) The heatmap plotted through the results from qRT-PCR told us that miR-370-3p was the most up-regulated miRNA in response to circAGFG1 down-regulation in CC cells.
Jingjing Zhou (179820), Fengqin Wu (7842029)   +1 more
core   +1 more source