Results 41 to 50 of about 274,131 (166)

miR-22-3p regulates HCC cell EMT, migration, and invasion through the miR-22-3p-CBL-SPRY2 axis.

, 2023
A. Immunoblotting of CBL and SPRY2 in the three cell lines: HepG2 mock cells, HepG2 overexpressing miR-22-3p cells, and HepG2 overexpressing miR-22-3p plus CBL cells. B.
Dahu Chen (528122), Shuaishuai Cui (11690234), Xing Wang (154377), Yuanyuan Chen (165812), Yunfei Guo (3601046)   +4 more
core   +1 more source

Wnt7a and miR-370-3p: new contributors to bladder cancer invasion

Biotarget, 2018
In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.
Danielle, Scheunemann, Anjan K, Pradhan, Swadesh K, Das, Devanand, Sarkar, Luni, Emdad, Paul B, Fisher   +5 more
openaire   +2 more sources

Yinchenhao Decoction Protects Against Intrahepatic Cholestasis During Pregnancy Through the miR-370-3p/TM9SF4/KIT Axis. [PDF]

Biomed Res Int
Objective: The objective is to explore the potential pathogenesis and therapeutic mechanism of Yinchenhao decoction (YCHD) in intrahepatic cholestasis of pregnancy (ICP) by focusing on the regulatory role of exosomal miR‐370‐3p on target genes TM9SF4 and KIT.
Jiang H, Yu W, Tao X, Yan Q, Zhou G, Chen C, Han G.   +6 more
europepmc   +4 more sources

Up-regulation of miR-370-3p restores glioblastoma multiforme sensitivity to temozolomide by influencing MGMT expression [PDF]

Scientific Reports, 2016
AbstractMicroRNAs (miRNA) are believed to play an important role in glioblastoma multiforme (GBM)chemotherapy. Our study aims to investigate potential miRNA biomarkers in GBM. Sixty GBM patients, which were given temozolomide (TMZ) chemotherapy and recurrent radiotherapy, were recruited.
Yong-tao Gao, Xiao-bing Chen, Hong-lin Liu   +2 more
openaire   +2 more sources

Image_2_Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis.TIF

, 2022
BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Litong Zhu (6578963), Zhuomin Huang (13951260), Quanfu Zhang (158693), Jilong Yao (13951263), Depeng Zhao (1608115)   +4 more
core   +1 more source

Endogenous and viral microRNAs in nasal secretions of water buffaloes (Bubalus bubalis) after Bubaline alphaherpesvirus 1 (BuHV-1) challenge infection

Veterinary Research, 2023
Bubaline alphaherpesvirus 1 (BuHV-1) is a pathogen of water buffaloes responsible for economic loss worldwide. MicroRNAs (miRNAs) regulate gene expression produced by alphaherpesviruses and hosts. This study aimed at (a) unravelling the ability of BuHV-1
Cristina Lecchi, Fabrizio Ceciliani, Stefano Petrini, Giovanna Cappelli, Carlo Grassi, Anna Balestrieri, Giorgio Galiero, Ester DeCarlo, Gaspare Salvi, Filippo Panzeri, Chiara Gini, Alessandra Cafiso, Alessandro Agazzi, Alessandra Martucciello   +13 more
doaj   +1 more source

Image_1_Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis.TIF

, 2022
BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Litong Zhu (6578963), Zhuomin Huang (13951260), Quanfu Zhang (158693), Jilong Yao (13951263), Depeng Zhao (1608115)   +4 more
core   +1 more source

Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B

Stem Cell Research & Therapy, 2019
Background Human bone marrow-derived mesenchymal stem cells (HBMSCs) are characterized by multiple differentiation potential and potent self-renewal ability, yet much remains to be elucidated on what determines these properties. Long-chain noncoding RNAs
Bo Jia, Zhiping Wang, Xiang Sun, Jun Chen, Jianjiang Zhao, Xiaoling Qiu   +5 more
doaj   +1 more source

Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling

Molecular Therapy: Nucleic Acids, 2020
To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied the effects of this disease on the expression of microRNAs (miRNAs) in the lung.
Xuemin Gao, Dingjie Xu, Shumin Li, Zhongqiu Wei, Shifeng Li, Wenchen Cai, Na Mao, Fuyu Jin, Yaqian Li, Xue Yi, Heliang Liu, Hong Xu, Fang Yang   +12 more
doaj   +1 more source

CircASPH Promotes Hepatocellular Carcinoma Progression Through Methylation and Expression of HAO2

Frontiers in Oncology, 2022
CircRNAs have been reported to be related to hepatocellular carcinoma (HCC) development. Limited studies have revealed the expression profile of circRNAs in tumor and para-tumor normal samples in HCC patients.
Han Zhuo, Jinguo Xia, Jin Zhang, Junwei Tang, Sheng Han, Qitong Zheng, Deming Zhu, Feihong Zhang, Zhenggang Xu, Dongwei Sun, Zhongming Tan, Chen Wu   +11 more
doaj   +1 more source