Results 41 to 50 of about 70 (69)

CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p

Scientific Reports
Circular RNA (circRNA) is a unique closed ring structure of noncoding RNA. Although many human diseases have been confirmed to be inextricably linked with circRNAs, whether circRNAs have a potential regulatory function in the osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs) remains to be further elucidated.
Lei Zhang, Yidan Xu, Ningning Liu, Mengjie Xu, Refeina Tuerxun, Mireyeti Shahatibieke, Yuan Yao   +6 more
openaire   +3 more sources

Circ_0020887 Silencing Combats Hypoxic-Induced Cardiomyocyte Injury in an MiR-370-3p/CYP1B1-Dependent Manner

International Heart Journal
Targeting circular RNA has been a novel approach to preventing and limiting acute myocardial infarction (AMI). Here, we planned to investigate the role and mechanism of circ_0020887 in AMI progression.Hypoxic injury in human cardiomyocytes (AC16) was measured using cell counting kit-8 assay, 5-ethynyl-2'-deoxyuridine assay, flow cytometry, and ...
Chen, Huiqin, Cheng, Zhendong, Wang, Meiai, Huang, Qian, Zheng, Dandan, Huang, Qiuhong, Cai, Kefeng   +6 more
openaire   +2 more sources

SNHG15 is involved in the progression of atherosclerosis through targeted regulation of miR-370-3p and bioinformatics analysis

Archives of Medical Science
IntroductionThis study aimed to explore the expression of SNHG15 in atherosclerotic population and further evaluate the regulatory mechanism of SNHG15 in AS.Material and methodsqRT-PCR was used to detect the level of SNHG15 in serum samples. An in vitro cell model was constructed using 50 µg/ml ox-LDL-induced VSMCs.
Wan Pan, Yan Zhou, Fan Zhang, Yingying Zhang, Wei Li, Chengpeng Li, Liqun He   +6 more
openaire   +1 more source

MiR-370-3P inhibits proliferation of human articular chondrocytes by regulating JAK2/STAT5B signaling pathway

Di-san junyi daxue xuebao, 2021
Objective To investigate whether the non-coding single chain RNA miR-370-3P regulates the proliferation of human articular chondrocytes (HC-a) through the JAK2/STAT5B signaling pathway and to explore its potential mechanism. Methods The over- /under-expression of miR-370-3P models were constructed by transfecting HC-a cells, and then the cells were ...
CHEN Lanni, ZHANG Huijiao, XU Xuejiao, XU Ke, ZHU Min   +4 more
openaire   +1 more source

Hsa_circ_0009096/miR-370-3p modulates hepatic stellate cell proliferation and fibrosis during biliary atresia pathogenesis

PeerJ
Background Hepatic stellate cell (HSC) activation and hepatic fibrosis mediated biliary atresia (BA) development, but the underlying molecular mechanisms are poorly understood. This study aimed to investigate the roles of circRNA hsa_circ_0009096 in the regulation of HSC proliferation and hepatic fibrosis.
Wu, Zhouguang, Wang, Bin, Chen, Siqi, Zuo, Taoyan, Zhang, Wenjie, Cheng, Zhen, Fu, Jingru, Gong, Jiafeng   +7 more
openaire   +3 more sources

Increased plasma miR-370-3p expression in poor-outcome patients with pancreatic ductal adenocarcinoma [PDF]

Increased plasma miR-370-3p expression in poor-outcome patients with pancreatic ductal adenocarcinoma
広島大学
openaire   +3 more sources

Yinchenhao Decoction Protects Against Intrahepatic Cholestasis During Pregnancy Through the miR‐370‐3p/TM9SF4/KIT Axis

BioMed Research International
Objective: The objective is to explore the potential pathogenesis and therapeutic mechanism of Yinchenhao decoction (YCHD) in intrahepatic cholestasis of pregnancy (ICP) by focusing on the regulatory role of exosomal miR‐370‐3p on target genes TM9SF4 and KIT.
Hongxiu Jiang, Wenjing Yu, Xingran Tao, Qiao Yan, Guanlun Zhou, Chao Chen, Guorong Han   +6 more
openaire   +3 more sources

Transcriptomic analysis revealed that oar-miR-370-3p was involved in the regulation of wool fineness in Ordos fine-wool sheep

Frontiers in Veterinary Science
MicroRNA (miRNA) is a prominent topic in biological research, as it plays a crucial role in regulating various physiological processes. Identifying miRNAs associated with fiber traits enhances our understanding of the complex biological mechanisms involved in hair follicle development and provides potential targets for improving ...
Wu, Cuiling, Amar, Gvlnigar, Anwar, Asma, Liu, Wenna, Tang, Sen, Ma, Shengchao, Fu, Xuefeng   +6 more
openaire   +2 more sources

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CircSPI1_005 ameliorates osteoarthritis by sponging miR-370-3p to regulate the expression of MAP3K9

International Immunopharmacology, 2022
Osteoarthritis (OA), caused by the destruction of joint cartilage, is the most prevalent form of arthritis, causing pain and stiffness in joints among millions of patients worldwide. Increasing evidence suggests that non-coding RNAs, including circular RNAs, play important roles in the pathogenesis of OA, but the precise signaling pathway is still ...
Jian-Lin, Zhou, Shuang, Deng, Hong-Song, Fang, Hao, Peng, Qiong-Jie, Hu   +4 more
openaire   +2 more sources

Increased plasma miR-370-3p expression in poor-outcome patients with pancreatic ductal adenocarcinoma

Pancreatology, 2023
To determine whether circulating microRNAs (miRNAs) can be used as prognostic biomarkers for pancreatic ductal adenocarcinoma (PDAC).Patients with PDAC (N = 120) who underwent surgical resection at Hiroshima University Hospital between November 2006 and January 2020 were enrolled in this study and grouped based on their overall survival (OS) into two ...
Takumi Harada, Kenichiro Uemura, Tatsuaki Sumiyoshi, Ryuta Shintakuya, Kenjiro Okada, Tetsuhiro Hara, Shinya Takahashi, Eiso Hiyama   +7 more
openaire   +2 more sources