circITGA7 Acts as a miR-370-3p Sponge to Suppress the Proliferation of Prostate Cancer. [PDF]
J Oncol, 2021 Abstract Objective: Prostate cancer (PCa) refers to one of the most common tumors in male’s genitourinary system. Emerging research has confirmed that circRNAs play an important role in the occurrence and development of tumors. However, the correlation between circular RNA circITGA7 and PCa still remains unclear.
Luo G +5 more
europepmc +4 more sources
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway. [PDF]
Int J Biol Sci, 2022 Increasing evidence suggests that circular RNAs (circRNAs) are involved in regulating tumor biological activity. Glioblastoma (GBM) is one of the most lethal diseases characterized by highly aggressive proliferative and invasive behaviors. We aimed to explore how circRNAs influenced GBM biological activity.
Li B, Chen J, Wu Y, Luo H, Ke Y.
europepmc +3 more sources
Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats. [PDF]
G3 (Bethesda), 2021 Abstract MicroRNAs (miRNAs), a class of 22 nucleotide (nt) noncoding RNAs, negatively regulate mRNA posttranscriptional modification in various biological processes. Morphogenesis of skin hair follicles in cashmere goats is a dynamic process involving many key signaling molecules, but the associated cellular biological mechanisms induced
Hai E +16 more
europepmc +5 more sources
Inhibition of intervertebral disc disease progression via the circPKNOX1-miR-370-3p-KIAA0355 axis. [PDF]
Cell Death Discov, 2021 AbstractThe molecular mechanism underlying the development of intervertebral disc disease (IVDD) is not completely understood. Circular RNAs (circRNAs) play a significant role in the occurrence and development of various diseases, and studies have shown that circPKNOX1 is involved in the compensatory response of extracellular matrix synthesis and ...
Huang Y +8 more
europepmc +5 more sources
The Potential of miR-370-3p and miR-495-3p Serving as Biomarkers for Sepsis-Associated Acute Kidney Injury. [PDF]
Comput Math Methods Med, 2022 Objective. This study is aimed at evaluating the miR-370-3p and miR-495-3p expression in the urine of patients with sepsis-associated acute kidney injury (SA-AKI) and exploring its diagnosis value in for SA-AKI. Methods. 184 sepsis invalids were collected and divided two groups (non-AKI group or AKI group) according to whether they had acute kidney ...
Ma W +5 more
europepmc +3 more sources
lncRNA SNHG15 Promotes Ovarian Cancer Progression through Regulated CDK6 via Sponging miR-370-3p. [PDF]
Biomed Res Int, 2021 Ovarian cancer is a kind of cancer from the female genital tract; the molecular mechanism still needs to be explored. lncRNA plays a vital role in tumorigenesis and development. Our aim was to identify oncogenic lncRNAs in ovarian cancer and explore the potential molecular mechanism.
Wang Y +7 more
europepmc +3 more sources
Circ_UBE2D2 Attenuates the Progression of Septic Acute Kidney Injury in Rats by Targeting miR-370-3p/NR4A3 Axis. [PDF]
J Microbiol Biotechnol, 2022 As circ_UBE2D2 has been confirmed to have targeted binding sites with multiple miRNAs involved in septic acute kidney injury (SAKI), efforts in this study are directed to unveiling the specific role and relevant mechanism of circ_UBE2D2 in SAKI. HK-2 cells were treated with lipopolysaccharide (LPS) to construct SAKI model in vitro. After sh-circ_UBE2D2
Huang Y, Zheng G.
europepmc +3 more sources
Silencing miR-370-3p rescues funny current and sinus node function in heart failure. [PDF]
Sci Rep, 2020 AbstractBradyarrhythmias are an important cause of mortality in heart failure and previous studies indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel HCN4 in this process. Here we show that, in a mouse model of heart failure in which there is sinus bradycardia, there is upregulation of a microRNA (miR-370-3p ...
Yanni J +27 more
europepmc +9 more sources
LncMyoD Promotes Skeletal Myogenesis and Regulates Skeletal Muscle Fiber-Type Composition by Sponging miR-370-3p. [PDF]
Genes (Basel), 2021 The development of skeletal muscle is a highly ordered and complex biological process. Increasing evidence has shown that noncoding RNAs, especially long-noncoding RNAs (lncRNAs) and microRNAs, play a vital role in the development of myogenic processes.
Zhang P +15 more
europepmc +4 more sources
Circ_0010729 knockdown protects cardiomyocytes against hypoxic dysfunction via miR-370-3p/TRAF6 axis. [PDF]
EXCLI J, 2020 EXCLI Journal; 19:Doc1520; ISSN 1611 ...
Zhang J, Gao C, Zhang J, Ye F.
europepmc +4 more sources