Results 21 to 30 of about 5,620 (185)

Hsa_circ_0009096/miR-370-3p modulates hepatic stellate cell proliferation and fibrosis during biliary atresia pathogenesis [PDF]

PeerJ
Background Hepatic stellate cell (HSC) activation and hepatic fibrosis mediated biliary atresia (BA) development, but the underlying molecular mechanisms are poorly understood.
Zhouguang Wu, Bin Wang, Siqi Chen, Taoyan Zuo, Wenjie Zhang, Zhen Cheng, Jingru Fu, Jiafeng Gong   +7 more
doaj   +5 more sources

The influence of concentration of micro-rna hsa-mir-370-3p and CYP2D6*4 on equilibrium concentration of mirtazapine in patients with major depressive disorder [PDF]

European Psychiatry, 2021
Introduction Mirtazapine is commonly prescribed to patients diagnosed with major depressive disorder.Some proportion of these patients do not show adequate response to treatment regimen containing mirtazapine, whereas many of them experience dose ...
M. Zastrozhin, V. Skryabin, D. Sychev, E. Bryun   +3 more
doaj   +4 more sources

circITGA7 Acts as a miR-370-3p Sponge to Suppress the Proliferation of Prostate Cancer. [PDF]

J Oncol, 2021
Abstract Objective: Prostate cancer (PCa) refers to one of the most common tumors in male’s genitourinary system. Emerging research has confirmed that circRNAs play an important role in the occurrence and development of tumors. However, the correlation between circular RNA circITGA7 and PCa still remains unclear.
Luo G, Li G, Wan Z, Zhang Y, Liu D, Guo Y.   +5 more
europepmc   +6 more sources

Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats. [PDF]

G3 (Bethesda), 2021
Abstract MicroRNAs (miRNAs), a class of 22 nucleotide (nt) noncoding RNAs, negatively regulate mRNA posttranscriptional modification in various biological processes. Morphogenesis of skin hair follicles in cashmere goats is a dynamic process involving many key signaling molecules, but the associated cellular biological mechanisms induced
Hai E, Han W, Wu Z, Ma R, Shang F, Wang M, Liang L, Rong Y, Pan J, Wang Z, Wang R, Su R, Zhao Y, Liu Z, Wang Z, Li J, Zhang Y.   +16 more
europepmc   +6 more sources

Knockdown of circ_NEK6 Decreased I Resistance of Differentiated Thyroid Carcinoma via Regulating miR-370-3p/MYH9 Axis [PDF]

Technology in Cancer Research & Treatment, 2021
Radioresistance is a crucial factor for the failure of iodine 131 ( 131 I)-based radiotherapy for differentiated thyroid carcinoma (DTC). This study aimed to explore the effect of circ_NEK6 on the development of 131 I resistance in DTC and its potential ...
Fukun Chen, Shuting Yin, Zhiping Feng, Chao Liu, Juan Lv, Yuanjiao Chen, Ruoxia Shen, Jiaping Wang, Zhiyong Deng   +8 more
doaj   +3 more sources

Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway. [PDF]

Int J Biol Sci, 2022
Increasing evidence suggests that circular RNAs (circRNAs) are involved in regulating tumor biological activity. Glioblastoma (GBM) is one of the most lethal diseases characterized by highly aggressive proliferative and invasive behaviors. We aimed to explore how circRNAs influenced GBM biological activity.
Li B, Chen J, Wu Y, Luo H, Ke Y.
europepmc   +5 more sources

LncMyoD Promotes Skeletal Myogenesis and Regulates Skeletal Muscle Fiber-Type Composition by Sponging miR-370-3p [PDF]

Genes, 2021
The development of skeletal muscle is a highly ordered and complex biological process. Increasing evidence has shown that noncoding RNAs, especially long-noncoding RNAs (lncRNAs) and microRNAs, play a vital role in the development of myogenic processes.
Peiwen Zhang, Jin He, Linyuan Shen
exaly   +5 more sources

lncRNA BCAR4 sponges miR‑370‑3p to promote bladder cancer progression via Wnt signaling. [PDF]

Int J Mol Med, 2020
Accumulating evidence suggests that the aberrant expression of long non‑coding RNAs (lncRNAs) is involved in the initiation, development and metastasis of bladder cancer (BC). Although several differentially expressed lncRNAs have been identified via lncRNA expression profiling of BC tissues, their functions and the molecular mechanisms underlying ...
Zhang R, Wang J, Jia E, Zhang J, Liu N, Chi C.   +5 more
europepmc   +5 more sources

Inhibition of intervertebral disc disease progression via the circPKNOX1-miR-370-3p-KIAA0355 axis. [PDF]

Cell Death Discov, 2021
AbstractThe molecular mechanism underlying the development of intervertebral disc disease (IVDD) is not completely understood. Circular RNAs (circRNAs) play a significant role in the occurrence and development of various diseases, and studies have shown that circPKNOX1 is involved in the compensatory response of extracellular matrix synthesis and ...
Huang Y, Gao J, Wang J, Ye H, Yao T, Xu Y, Chen Z, Shen S, Ma J.   +8 more
europepmc   +6 more sources

Silencing miR-370-3p rescues funny current and sinus node function in heart failure. [PDF]

Sci Rep, 2020
AbstractBradyarrhythmias are an important cause of mortality in heart failure and previous studies indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel HCN4 in this process. Here we show that, in a mouse model of heart failure in which there is sinus bradycardia, there is upregulation of a microRNA (miR-370-3p ...
Yanni J, D'Souza A, Wang Y, Li N, Hansen BJ, Zakharkin SO, Smith M, Hayward C, Whitson BA, Mohler PJ, Janssen PML, Zeef L, Choudhury M, Zi M, Cai X, Logantha SJRJ, Nakao S, Atkinson A, Petkova M, Doris U, Ariyaratnam J, Cartwright EJ, Griffiths-Jones S, Hart G, Fedorov VV, Oceandy D, Dobrzynski H, Boyett MR.   +27 more
europepmc   +10 more sources