Results 21 to 30 of about 45,933 (126)

mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats. [PDF]

Endocrinology, 2018
Growth plate chondrocytes undergo sequential differentiation to form the resting zone, the proliferative zone (PZ), and the hypertrophic zone (HZ). The important role of microRNAs (miRNAs) in the growth plate was previously revealed by cartilage-specific ablation of Dicer, an enzyme essential for biogenesis of many miRNAs.
Jee YH, Wang J, Yue S, Jennings M, Clokie SJ, Nilsson O, Lui JC, Baron J.   +7 more
europepmc   +5 more sources

Author Correction: hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p. [PDF]

Sci Rep
Figure
Huang S, Liu K, Xu Y, Wang H, Fu S, Wu J.   +5 more
europepmc   +4 more sources

MicroRNA-379-5p attenuates cancer stem cells and reduces cisplatin resistance in ovarian cancer by regulating RAD18/Polη axis [PDF]

Cell Death and Disease
Ovarian cancer (OC) is an aggressive malignancy of the female reproductive organs, associated with a low 5-year survival rate. Emerging evidence suggests the pivotal role of microRNAs (miRNAs) in regulating chemoresistance and metastasis in OC, primarily
Devendra Shukla, Sanjay Mishra, Tanima Mandal, Manish Charan, Ajeet Kumar Verma, Md Maqsood Ahamad Khan, Nabanita Chatterjee, Amit Kumar Dixit, Senthil Kumar Ganesan, Ramesh K. Ganju, Amit Kumar Srivastava   +10 more
doaj   +3 more sources

HGG-05. miR-379-5p REGULATES PROLIFERATION, MIGRATION AND INVASION IN BRAF MUTANT-GLIOBLASTOMA [PDF]

Neuro Oncol, 2018
Zhang R, Li K, Ng H.
europepmc   +4 more sources

miR-379-5p inhibits proliferation and invasion of the endometrial cancer cells by inhibiting expression of ROR1

Acta Biochimica Polonica, 2021
Endometrial cancer is a common gynecological malignancy, and the incidence of this disease has increased in recent years. Recently, some studies suggested that the expression of miR-379-5p suppressed the metastasis of breast cancer cells. However, whether the expression of miR-379-5p could affect the proliferation, migration and invasion of endometrial
Minglin, Liang, Hui, Chen, Jie, Min
openaire   +4 more sources

MicroRNA‐379‐5p targets MAP3K2 to reduce autophagy and alleviate neuronal injury following cerebral ischemia via the JNK/c‐Jun signaling pathway

Kaohsiung Journal of Medical Sciences, 2022
MicroRNAs (miRNAs) are abundant in neurons and play key roles in the function and development of the nervous system. This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke.
Yun Mo, Yin‐Yi Sun, Erli Yue, Yuan Liu, Kang‐Yong Liu   +4 more
doaj   +2 more sources

MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis

Molecular Biomedicine, 2022
Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Yunxia Dong, Chuwei Yu, Ningning Ma, Xiaoding Xu, Qian Wu, Henglei Lu, Likun Gong, Jing Chen, Jin Ren   +8 more
doaj   +2 more sources

AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p

Cellular Signalling, 2021
Drug resistance is an important cause of death for most patients with chronic myeloid leukemia (CML). The bone marrow microenvironment is believed to be mainly responsible for resistance to BCR-ABL tyrosine kinase inhibitors. The mechanism involved, however, is still unclear.Bioinformatic analysis from GEO database of AKR1C3 was utilized to identify ...
Di, Pan, Wanwan, Yang, Yao, Zeng, Wenjun, Li, Kaizhen, Wang, Li, Zhao, Jia, Li, Yuting, Ye, Qinglong, Guo   +8 more
openaire   +3 more sources

MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells

Cancer Management and Research, 2020
Fei Zhang,1 Chuanxin Duan,1 Shucheng Yin,2 Ying Tian1 1Department of Otolaryngology, Maternal and Child Health Care Hospital of Hubei Province and Women and Children’s Hospital of Hubei Province, Wuhan 430070, People’s Republic of China ...
Zhang F, Duan C, Yin S, Tian Y
doaj   +2 more sources

MiR-379-5p improved locomotor function recovery after spinal cord injury in rats by reducing endothelin 1 and inhibiting astrocytes expression.

European review for medical and pharmacological sciences, 2019
The aim of this study was to investigate the effect of microRNA-214-5p (miR-214-5p) on spinal cord injury (SCI) and to explore the mechanism of action in pathophysiological relevance.The model of SCI was successfully established in rats aged 6-8 weeks.
A, J.-C., Li, Z.-Y., Long, Q.-F., Wang, D.-Y., Zhao, H.-S., Jia, S.-L., Zhang, W.-H.   +6 more
openaire   +3 more sources