Results 91 to 100 of about 5,056 (201)

IL-4 Up-Regulates MiR-21 and the MiRNAs Hosted in the CLCN5 Gene in Chronic Lymphocytic Leukemia. [PDF]

PLoS ONE, 2015
Interleukin 4 (IL-4) induces B-cell differentiation and survival of chronic lymphocytic leukemia (CLL) cells. MicroRNAs (miRNAs) regulate mRNA and protein expression, and several miRNAs, deregulated in CLL, might play roles as oncogenes or tumor ...
Natalia Ruiz-Lafuente, María-José Alcaraz-García, Silvia Sebastián-Ruiz, Azahara-María García-Serna, Joaquín Gómez-Espuch, José-María Moraleda, Alfredo Minguela, Ana-María García-Alonso, Antonio Parrado   +8 more
doaj   +1 more source

Resolution of inflammation: what Controls its Onset? [PDF]

, 2016
The authors would like to acknowledge the funding agencies, Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brazil), Comissão de Aperfeiçoamento de Pessoal do Ensino Superior (CAPES, Brazil), Fundação do Amparo a Pesquisa de Minas ...
Alessandri, Anderson, Anderson, Anderson, Aparicio-Soto, Arita, Averill, Baeuerle, Bamias, Bandeira-Melo, Baumgart, Bazzoni, Bersudsky, Besedovsky, Bhatt, Biswas, Bohuslav, Boldin, Boldin, Bonizzi, Bozyk, Brancaleone, Brancaleone, Branzk, Brophy, Brudecki, Brun, Buckley, Burne, Butler, Campbell, Cataldi, Celik, Chan, Cheng, Chian, Chiang, Cipollone, Claria, Corbin, Coskun, Criollo, Csoka, Dalli, Dalli, Damo, Danese, Dean, Dean, Diaz-Ochoa, Dupaul-Chicoine, Eke Gungor, El Gazzar, El-Salhy, Erlinger, Etzrodt, Fadok, Fiorucci, Fong, Fu, Fukunaga, Garcia-Romo, Gasser, Gastardelo, Gearing, Getting, Gilroy, Gobbetti, Gresnigt, Greten, Hakkim, Haq, Harrington, Harty, Hasko, Haworth, Haworth, Hayden, Headland, Headland, Helgadottir, Heppner, Hodges, Hoffmann, Hong, Hood, Hosokawa, Hsu, Hsu, Huang, Huxford, Johnnidis, Jurkin, Kahlenberg, Karin, Katakami, Kehl-Fie, Kim, Knight, Knight, Koroskenyi, Kuhl, Kunkel, Lagos, Lande, Lardone, Lawrence, Lawrence, Lawrence, Lee, Leoni, Letterio, Levy, Levy, Li, Liu, Liu, Lood, Lopes, Loser, Lu, Ma, Ma, Ma, MacKenzie, Maderna, Malawista, Mangino, Markworth, Martinod, Mazumder, McQuibban, McQuibban, McQuibban, Medina-Contreras, Medzhitov, Medzhitov, Mirakaj, Moelants, Monteleone, Monteleone, Montero-Melendez, Montero-Melendez, Montero-Melendez, Morris, Morris, Muxel, Nakahira, Nathan, Nathan, Nemeth, Newton, Nibbs, Oeckinghaus, Opie, Ortega-Gomez, Otsuka, Ouyang, O’Connell, Parks, Pavlov, Pederzoli-Ribeil, Pepper, Perretti, Perretti, Perretti, Perretti, Perry, Pillai, Planaguma, Planagumà, Podolska, Porta, Rau, Riva, Ronchetti, Ryckman, Saccani, Saitoh, Samuelsson, Saraiva, Savchenko, Scannell, Schaljo, Schauer, Schiopu, Schwab, Schwartz, Sena, Sena, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Serhan, Shaked, Shibata, Shimizu, Sohnle, Sousa, Souza, Souza, Souza, Souza, Sroussi, Sroussi, Sroussi, Sroussi, Stables, Sugimoto, Sun, Sun, Surh, Taganov, Takagi, Tam, Terrin, Trostrup, Vacchini, Vachier, Vago, Vallabhapurapu, van den Bergh, Van den Steen, van der Meer, Vancheri, Vane, Villani, Viola, Vogl, Volz, Vong, Vordenbaumen, Wallace, Wang, Warnatsch, Wilborn, Wilson, Wong, Woo, Wu, Xiao, Youssef, Zaki, Zhang, Zhong, Zhou, Ziegler-Heitbrock   +250 more
core   +3 more sources

Аналіз зв’язку поліморфізму rs4977574 гена ANRIL із розвитком раку нирки в українській популяції [PDF]

, 2020
ANRIL (Antisense Non-coding RNA in the INK4 Locus, also known as CDKN2B-AS1) – 3.8-kb long non-coding RNA transcribed from the antisense strand of INK4b-ARF-INK4a gene cluster.
Ataman, Oleksandr Vasylovych, Harbuzova, Viktoriia Yuriivna, Volkohon, Andrii Dmytrovych, Атаман, Александр Васильевич, Атаман, Олександр Васильович, Волкогон, Андрей Дмитриевич, Волкогон, Андрій Дмитрович, Гарбузова, Виктория Юрьевна, Гарбузова, Вікторія Юріївна   +8 more
core   +1 more source

Circ‐0030167/IGF2BP1 Induces Mitophagy‐Mediated Ferroptosis via HMOX1 mRNA Stabilization in Pancreatic Cancer

Cancer Science, Volume 117, Issue 5, Page 1362-1379, May 2026.
Our findings identify circ‐0030167/IGF2BP1/HMOX1 axis as a critical regulatory factor targeting mitochondria‐mediated ferroptosis, thereby presenting a novel therapeutic target for PC combination therapies. ABSTRACT Pancreatic cancer (PC) represents a highly aggressive malignancy characterized by a 5 year survival rate of less than 12%.
Qun Zhao, Xihao Yao, Jingjing Lu, Qiyang Chen, Zhiwei Wang, Xiaohong Li, Yuhua Lu   +6 more
wiley   +1 more source

Circulating miRNAs Correlate With rIPC‐Induced Cardioprotection and Its Impairment in Diabetic Myocardial Infarction via AMPK Signalling

Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.
ABSTRACT Remote ischemic preconditioning (rIPC) has shown potential in protecting myocardial tissue against acute myocardial infarction (AMI), primarily through anti‐apoptotic, anti‐inflammatory, and anti‐hypoxic mechanisms. However, its effectiveness is compromised in the presence of metabolic comorbidities such as diabetes.
Yeyi Bai, Bang'e Zhao, Tingting Liu, Bei Tian, Haijian Liu   +4 more
wiley   +1 more source

Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-κB Signaling Pathway and Affecting the Apoptosis and Signal Transduction

Genetics Research, 2022
Background. Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma with high heterogeneity. There is an unmet need to investigate valid indicators for the diagnosis and therapy of DLBCL. Methods.
Chunyao Li, Lanshan Huang, Yongqin Wen, Muhua Yi, Min Gao   +4 more
doaj   +1 more source

A 2 miRNAs-based signature for the diagnosis of atherosclerosis

BMC Cardiovascular Disorders, 2021
Background Atherosclerosis (AS) is a leading cause of vascular disease worldwide. MicroRNAs (miRNAs) play an essential role in the development of AS. However, the miRNAs-based biomarkers for the diagnosis of AS are still limited.
Xiujiang Han, Huimin Wang, Yongjian Li, Lina Liu, Sheng Gao   +4 more
doaj   +1 more source

MicroRNA-532-5p Regulates Pericyte Function by Targeting the Transcription Regulator BACH1 and Angiopoietin-1 [PDF]

, 2018
MicroRNAs regulate endothelial function and angiogenesis, but their implication in pericyte biology remains undetermined. A PCR array, covering a panel of 379 human microRNAs, showed microRNA-532-5p to be one of the most differentially modulated by ...
Alvino, Valeria V., Caporali, Andrea, Jover, Eva, Madeddu, Paolo, Martello, Andrea, Mitić, Tijana, Rodriguez-arabaolaza, Iker, Satchell, Simon C., Slater, Sadie C., Spinetti, Gaia, Vono, Rosa   +10 more
core   +3 more sources

Additional file 3 of lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p

, 2022
Additional file 3: Table S1. The sequences of PCR primers.
Peng, Yi, Huang, Xiaoxi, Wang, Hongmei
openaire   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source