Results 81 to 90 of about 5,056 (201)

Role of miRNA-mRNA Interaction in Neural Stem Cell Differentiation of Induced Pluripotent Stem Cells [PDF]

, 2020
miRNA regulates the expression of protein coding genes and plays a regulatory role in human development and disease. The human iPSCs and their differentiated progenies provide a unique opportunity to identify these miRNA-mediated regulatory mechanisms ...
Blangero, John, Curran, Joanne E., De Leon, Erica, Glahn, David C., Howard, Tom E., Kumar, Satish, Leandro, Ana C., Lehman, Donna M., Williams-Blangero, Sarah   +8 more
core   +2 more sources

Unveiling coralline diversity of mesophotic rhodoliths in subtropical Japan, including new species of Sporolithon, emended genera Orientalilithon and Roseolithon (Corallinophycidae, Rhodophyta)

Journal of Phycology, EarlyView.
Abstract The mesophotic zone off Tanegashima Island (approximately 30–40 m deep) is a marine macroalgal hotspot in subtropical Japan; however, the taxonomic diversity of calcifying red algal community remains poorly understood. Our phylogenetic analyses based on psbA, rbcL, and COI‐5P gene markers disclosed the presence of at least 12 rhodolith‐forming
Min‐Khant‐Kyaw, Masasuke Baba, Ryuta Terada, Aki Kato   +3 more
wiley   +1 more source

Relationship Between Coronary Atheroma, Epicardial Adipose Tissue Inflammation, and Adipocyte Differentiation Across the Human Myocardial Bridge

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin, Ingela Schnittger, Anna Nagy, Elizabeth Zanley, Yue Xu, Yanqiu Song, Koen Nieman, Jennifer A. Tremmel, Damini Dey, Jack Boyd, Harold Sacks   +10 more
doaj   +1 more source

Assessment Of Epsteın Barr Vırus Molecular Polymorphısm And Tumor Bıomarkers Assocıated Wıth Non- Hodgkın’s Lymphoma In Iraqı Patıents [PDF]

, 2022
The current study was conducted to evaluate the Epstein-Barr virus molecular polymorphism and tumor biomarkers associated with non-Hodgkin's lymphoma in Iraqi patients.
Aboomeıma, Wiqar Adnan Azeez
core  

Electrical pulse stimulation-induced tetanic exercise simulation increases the secretion of extracellular vesicles from C2C12 myotubes [PDF]

, 2023
Extracellular vesicles (EVs) released into the blood during exercise mediate its whole-body health effects. The differentiation of EVs released by skeletal muscle cells in vivo from those released by other cells is challenging, therefore, it is unclear ...
Akiyama, Hirokazu, Honda, Hiroyuki, Murata, Akari, Shimizu, Kazunori   +3 more
core   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

Advanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

Identification and validation of endogenous control miRNAs in plasma samples for normalization of qPCR data for Alzheimer’s disease

Alzheimer’s Research & Therapy, 2020
Background MicroRNAs (miRNAs) are noncoding RNAs that are highly relevant as disease biomarkers. Several studies that explored the role of miRNAs in Alzheimer’s disease (AD) demonstrated their usefulness in clinical identification.
F. Dakterzada, A. Targa, I. D. Benítez, L. Romero-ElKhayat, D. de Gonzalo-Calvo, G. Torres, A. Moncusí-Moix, R. Huerto, M. Sánchez-de-la-Torre, F. Barbé, G. Piñol-Ripoll   +10 more
doaj   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Serum microRNA profiles in patients with autosomal dominant polycystic kidney disease show systematic dysregulation partially reversible by hemodialysis

Archives of Medical Science, 2019
Introduction The impact of autosomal dominant polycystic kidney disease (ADPKD) on serum microRNAs (miRNA) is unknown. Material and methods For profiling experiment we recruited 30 patients from three equinumerous groups: controls, ADPKD and ADPKD on ...
Beata Małachowska, Marcin Tkaczyk, Sławomir Chrul, Rafał Zwiech, Wojciech Młynarski, Wojciech Fendler   +5 more
doaj   +1 more source

Altered microRNA profile during fracture healing in rats with diabetes

Journal of Orthopaedic Surgery and Research, 2020
Background MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that regulate gene expression. There is increasing evidence that some miRNAs are involved in the pathology of diabetes mellitus (DM) and its complications.
Shunsuke Takahara, Sang Yang Lee, Takashi Iwakura, Keisuke Oe, Tomoaki Fukui, Etsuko Okumachi, Michio Arakura, Yoshitada Sakai, Tomoyuki Matsumoto, Takehiko Matsushita, Ryosuke Kuroda, Takahiro Niikura   +11 more
doaj   +1 more source