Results 111 to 120 of about 4,926 (186)
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation [PDF]
, 2017 Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death. Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ancestry groups. To further define the
A Deshmukh +197 more
core +9 more sources
American journal of translational research, 2016 MicroRNAs (miRNAs) have been widely reported, which play important roles in cancer development. CXCL2 acts as an oncogene, however, its regulation by miRNAs is not clear in hepatocellular carcinoma (HCC). In our research, it is aimed to study the role of CXCL2 in HCC and the regulation of its expression by miRNAs.
Xiaofei, Song +4 more
openaire +1 more source
Human Molecular Genetics, 2019 AbstractYWHAE gene product belongs to the 14-3-3 protein family that mediates signal transduction in plants and mammals. Protein-coding and non-coding RNA (lncRNA) transcripts have been reported for this gene in human. Here, we aimed to functionally characterize YWHAE-encoded lncRNA in colorectal cancer-originated cells.
Hassan Bjeije +3 more
openaire +2 more sources
Animal, 2018 Circulating microRNAs (miRNAs) are emerging as promising biomarkers for several disorders and related pain. In equine practice, acute laminitis is a common disease characterised by intense pain that severely compromises horse welfare. Recently, the Horse
C. Lecchi +7 more
doaj +1 more source
Molecular Characterization of Peripheral Extracellular Vesicles in Clinically Isolated Syndrome: Preliminary Suggestions from a Pilot Study. [PDF]
, 2017 Extracellular vesicles (EVs), nanoparticles originated from different cell types, seem to be implicated in several cellular activities. In the Central Nervous System (CNS), glia and neurons secrete EVs and recent studies have demonstrated that the ...
Amoruso A +8 more
core +1 more source
microRNA blood signature for localized radiation injury
Scientific ReportsA radiological accident, whether from industrial, medical, or malicious origin, may result in localized exposure to high doses of ionizing radiations, leading to the development of local radiation injury (LRI), that may evolve toward deep ulceration and ...
Lucie Ancel +12 more
doaj +1 more source
Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application [PDF]
Background: Cytomegalovirus (CMV) infection is a relevant threat to heart-transplanted patients during the first year after surgery, leading to increased morbidity and, in some cases, mortality.
Abate D. +17 more
core +1 more source
Circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes [PDF]
, 2018 Exosomal microRNAs modulate cancer cell metabolism and the immune response. Specific exosomal microRNAs have been reported to be reliable biomarkers of several solid and hematologic malignancies.
Christopher K. Bleck +11 more
core +2 more sources
Cukurova Medical JournalPurpose: This study aims to investigate the expression profiles of hsa_circ_0025244 and hsa_circ_0001546 in breast tissue samples and to propose potential regulatory axes for these circular RNAs. Materials and Methods: The expression levels of hsa_circ_0025244 and hsa_circ_0001546 were determined in 55 tumor tissue samples (30 Luminal B and 25 Luminal
Fahrünnisa Abanoz +5 more
openaire +1 more source
Non-coding RNA ResearchBackground: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu +5 more
doaj +1 more source