Results 51 to 60 of about 6,191 (242)
Co-Activation of TGFβ and Wnt Signalling Pathways Abrogates EMT in Ovarian Cancer Cells [PDF]
, 2017 The aggressive property of ovarian cancer (OC) in terms of epithelialmesenchymal transition (EMT), proliferation and metastasis are of major concern. Different growth factors including TGFβ are associated with regulating these molecular events but the ...
Mitra, Tulika, Roy, Sib Sankar
core +1 more source
Cell Death and Disease, 2021 Aberrant microRNA (miR) expression plays an important role in pathogenesis of different types of cancers, including B-cell lymphoid malignancies and in the development of chemo-sensitivity or -resistance in chronic lymphocytic leukemia (CLL) as well as ...
Isha Kapoor +3 more
doaj +1 more source
Characteristics of Intronic and Intergenic Human miRNAs and Features of their Interaction with mRNA [PDF]
, 2011 International audienceRegulatory relationships of 686 intronic miRNA and 784 intergenic miRNAs with mRNAs of 51 intronic miRNA coding genes were established.
Atambayeva, Shara +5 more
core +2 more sources
APE1 controls DICER1 expression in NSCLC through miR-33a and miR-130b [PDF]
, 2022 Increasing evidence suggests different, not completely understood roles of microRNA biogenesis in the development and progression of lung cancer. The overexpression of the DNA repair protein apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) is an ...
Antoniali, Giulia +10 more
core +2 more sources
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline [PDF]
, 2010 <b>Objective</b>: MicroRNAs (miRNAs) are small noncoding RNAs that have the capacity to control protein production through binding "seed" sequences within a target mRNA. Each miRNA is capable of potentially controlling hundreds of genes.
Baker, Andrew H. +14 more
core +1 more source
MiR-543 inhibits proliferation and metastasis of human colorectal cancer cells by targeting PLAS3.
European review for medical and pharmacological sciences, 2020 Colorectal cancer (CRC) has a very high morbidity and mortality worldwide. Related studies have shown that microRNA-543 (miR-543) is involved in the development of many cancers, including CRC. The purpose of this study was to explore the potential molecular mechanism of miR-543's involvement in the development of CRC.QRT-PCR and Western blot were used ...
Su, D.-W. +5 more
openaire +2 more sources
Endometrial MIR-543 is down-regulated during the implantation window in women with endometriosis-related infertility [PDF]
Fertility and Sterility, 2018 Differentially expressed microRNAs (miRNAs) and their target mRNAs may lead to alterations in normal physiological status of the tissues and initiate pathological processes. The aim of this study was to investigate the expression of the most relevant miRNAs in the eutopic endometrial tissue during the window of implantation in women with endometriosis ...
Puyu, Yang +5 more
openaire +2 more sources
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the mechanism of lncRNA MEG3 (MEG3) modulating the proliferation and metastasis of pancreatic cancer cells via regulating miR-543/PTEN axis.
CHENG Jianxiao +4 more
doaj +1 more source
Animals, 2020 Arginine, a semi-essential functional amino acid, has been found to promote the synthesis of casein in mammary epithelial cells to some extent. Data from mouse indicated that microRNA (miRNA) are important in regulating the development of mammary gland ...
Xin Zhang +7 more
doaj +1 more source
Regulation of microRNA during cardiomyocyte maturation in sheep. [PDF]
, 2015 BACKGROUND: There is a limited capacity to repair damage in the mammalian heart after birth, which is primarily due to the inability of cardiomyocytes to proliferate after birth.
Botting, Kimberley J +6 more
core +2 more sources