Results 31 to 40 of about 215,132 (245)
miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4. [PDF]
Oncotarget, 2017 Till now, miR-543 expression has been demonstrated to be involved in the development of some cancers. However, reports about its expression and mechanism in colorectal cancer (CRC) were conflicting [1, 2]. Here, we investigated clinical implications of miR-543 and mechanisms underlying miR-543-mediated CRC development.
Zhai F, Cao C, Zhang L, Zhang J.
europepmc +4 more sources
MiR-543/SNTB1 axis modulates immune microenvironment in colorectal cancer
陆军军医大学学报Objective To investigate the clinical significance of the miR-543/syntrophin beta 1 (SNTB1) axis in colorectal cancer (CRC) and its influence on the tumor immune microenvironment.
ZHANG Min, LI Min, XIAO Meng
doaj +2 more sources
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway. [PDF]
J Cancer, 2019 Chemoresistance is responsible for most colorectal cancer (CRC) related deaths. In this study, we found that dichloroacetate (DCA), a pyruvate dehydrogenase kinase (PDK) inhibitor, can be used as a sensitizer for oxaliplatin (L-OHP) chemoresistant CRC cells.
Liang Y +13 more
europepmc +3 more sources
miR-543 impairs breast cancer cell phenotypes by targeting and suppressing ubiquitin-conjugating enzyme E2T (UBE2T) [PDF]
Bioengineered, 2021 Qing Li
exaly +2 more sources
MicroRNA-543 in systemic diseases and possible applications in gynecologic tumors
Reproductive and Developmental Medicine, 2021 In recent years, an increasing number of young women have been diagnosed with cancer, including some nulliparous women. Therefore, many young patients with early-stage cancer desire to preserve fertility after cytotoxic oncological treatments.
Yan-Ran Sheng +5 more
doaj +1 more source
World Journal of Surgical Oncology, 2021 Background The study was done to investigate the effect of LncRNA MEG3 on the immunity and autophagy of non-small cell lung carcinoma through the IDO signaling pathway. Methods A total of 78 cases of early NSCLC patients (research group; RG) and 69 cases
Chuanqiang Wang +2 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2021 Objective To investigate the role of LncRNAs-MEG3 in the carcinogenesis and progression of nasopharyngeal carcinoma (NPC) and the possible molecular mechanism. Methods qRT-PCR was used to detect the content of MEG3 and miR-543 in NPC cells.
NING Jiayu +4 more
doaj +1 more source
miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2 [PDF]
JCI InsightEnrique Fuentes-Mattei +29 more
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Frontiers in Neuroinformatics, 2022 ObjectiveIn our research we try to explore whether glioma stem cell containing circRNAs signal pathway could regulate glioma malignant progression and elaborate its possible mechanism.MethodsIn this study, we used biological information analysis to build
Li Guowei, Jin Yanping
doaj +1 more source
Integrated analysis of lncRNA-associated ceRNA network identified potential regulatory interactions in osteosarcoma [PDF]
Genetics and Molecular Biology, 2020 This study aimed to identify potential therapeutic targets in osteosarcoma (OS) through the network analysis of competing endogenous RNAs (ceRNAs). The differentially expressed miRNAs (DEMIs) and mRNAs (DEMs) were identified between OS cell lines and ...
Yongwei Wang +3 more
doaj +2 more sources