Results 31 to 40 of about 2,122,830 (164)
Higher miR-543 levels correlate with lower STK31 expression and longer pancreatic cancer survival. [PDF]
Cancer Med, 2020 AbstractPancreatic cancer (PC) is one of the most malignant gastrointestinal tumors and the 5‐year survival is only 9%. The expression of miRNAs in serum has been proved to be related to tumorigenesis and development of cancers. The miRNA targets and gene targets were predicted in microRNA.org, miRDB, TargetScan, and RNAInter.
Yuan W +6 more
europepmc +4 more sources
MicroRNA-543 in systemic diseases and possible applications in gynecologic tumors
Reproductive and Developmental Medicine, 2021 In recent years, an increasing number of young women have been diagnosed with cancer, including some nulliparous women. Therefore, many young patients with early-stage cancer desire to preserve fertility after cytotoxic oncological treatments.
Yan-Ran Sheng +5 more
doaj +1 more source
miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4. [PDF]
Oncotarget, 2017 Till now, miR-543 expression has been demonstrated to be involved in the development of some cancers. However, reports about its expression and mechanism in colorectal cancer (CRC) were conflicting [1, 2]. Here, we investigated clinical implications of miR-543 and mechanisms underlying miR-543-mediated CRC development.
Zhai F, Cao C, Zhang L, Zhang J.
europepmc +4 more sources
World Journal of Surgical Oncology, 2021 Background The study was done to investigate the effect of LncRNA MEG3 on the immunity and autophagy of non-small cell lung carcinoma through the IDO signaling pathway. Methods A total of 78 cases of early NSCLC patients (research group; RG) and 69 cases
Chuanqiang Wang +2 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2021 Objective To investigate the role of LncRNAs-MEG3 in the carcinogenesis and progression of nasopharyngeal carcinoma (NPC) and the possible molecular mechanism. Methods qRT-PCR was used to detect the content of MEG3 and miR-543 in NPC cells.
NING Jiayu +4 more
doaj +1 more source
miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2 [PDF]
JCI InsightEnrique Fuentes-Mattei +29 more
doaj +2 more sources
Frontiers in Neuroinformatics, 2022 ObjectiveIn our research we try to explore whether glioma stem cell containing circRNAs signal pathway could regulate glioma malignant progression and elaborate its possible mechanism.MethodsIn this study, we used biological information analysis to build
Li Guowei, Jin Yanping
doaj +1 more source
Integrated analysis of lncRNA-associated ceRNA network identified potential regulatory interactions in osteosarcoma [PDF]
Genetics and Molecular Biology, 2020 This study aimed to identify potential therapeutic targets in osteosarcoma (OS) through the network analysis of competing endogenous RNAs (ceRNAs). The differentially expressed miRNAs (DEMIs) and mRNAs (DEMs) were identified between OS cell lines and ...
Yongwei Wang +3 more
doaj +2 more sources
Design of crRNA to Regulate MicroRNAs Related to Metastasis in Colorectal Cancer Using CRISPR-C2c2 (Cas13a) Technique [PDF]
Cell Journal, 2023 Colorectal cancer (CRC) is the third most prevalent cancer with the second-highest mortality rate worldwide. microRNAs(miRNAs) of cancer-derived exosomes have shown promising diagnosis potential.
Seyed Taleb Houseini +4 more
doaj +1 more source
Endometrial MIR-543 is down-regulated during the implantation window in women with endometriosis-related infertility [PDF]
Fertility and Sterility, 2018 Differentially expressed microRNAs (miRNAs) and their target mRNAs may lead to alterations in normal physiological status of the tissues and initiate pathological processes. The aim of this study was to investigate the expression of the most relevant miRNAs in the eutopic endometrial tissue during the window of implantation in women with endometriosis ...
Puyu, Yang +5 more
openaire +2 more sources