MiR-543 Promotes Proliferation and Epithelial-Mesenchymal Transition in Prostate Cancer via Targeting RKIP [PDF]
Cellular Physiology and Biochemistry, 2017 Background/Aims: MicroRNAs (miRNAs, miRs) have emerged as important post-transcriptional regulators in various cancers. miR-543 has been reported to play critical roles in hepatocellular carcinoma and colorectal cancer, however, the role of miR-543 in ...
Yang Du +5 more
doaj +5 more sources
Placental Growth Factor Promotes Metastases of Ovarian Cancer Through MiR-543-Regulated MMP7
Cellular Physiology and Biochemistry, 2015 Background/Aims: Elucidation of the molecular mechanisms underlying ovarian cancer (OC) cell invasion and migration may provide important evidence for developing efficient therapy.
Ning Song +3 more
doaj +4 more sources
Roles of differential expression of miR-543-5p in GH regulation in rat anterior pituitary cells and GH3 cells. [PDF]
PLoS ONE, 2019 Growth hormone (GH) is an important hormone released by the pituitary gland that plays a key role in the growth and development of organisms. In our study, TargetScan analysis and the dual luciferase reporter assays were used to predict and screen for ...
Ze-Wen Yu +9 more
doaj +3 more sources
LncRNA PVT1 Regulates TRPS1 Expression in Breast Cancer by Sponging miR-543 [PDF]
Cancer Management and Research, 2020 Hongtao Wang,1,* Yuanli Huang,2,* Yuanrong Yang1 1Department of Pharmacy, The Second Clinical Medical College, Yangtze University, Jingzhou 434020, People’s Republic of China; 2Department of Galactophore, The Second Clinical Medical College ...
Wang H, Huang Y, Yang Y
doaj +5 more sources
LINC‐PINT alleviates lung cancer progression via sponging miR‐543 and inducing PTEN [PDF]
Cancer Medicine, 2020 Long intergenic nonprotein coding RNA p53‐induced transcript (LINC‐PINT) has been reported to participate in various cancers. Here, we investigated the effects of LINC‐PINT on lung cancer progression.
Shu Wang +7 more
doaj +5 more sources
Dysregulation of miR-543 in Parkinson's disease: Impact on the neuroprotective gene SIRT1. [PDF]
Neuropathol Appl Neurobiol, 2023 Aims: Parkinson's disease (PD) is a progressive and age-dependent neurodegenerative disease characterised clinically by a variety of motor symptoms and cognitive impairment.
Scheper M +5 more
europepmc +7 more sources
Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3. [PDF]
PLoS ONE, 2018 Molecular chaperones are important regulators of protein folding and proteasomal removal of misfolded proteins. In spinocerebellar ataxia type 3 (SCA3), the co-chaperone DnaJ homology subfamily B member 1 (DNAJB1 or heat shock protein 40) is recruited to
Bernd O Evert +9 more
doaj +4 more sources
miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2. [PDF]
JCI Insight, 2020 Myelofibros is (MF) is a myeloproliferative neoplasm characterized by cytopenia and extramedullary hematopoiesis, resulting in splenomegaly. Multiple pathological mechanisms (e.g., circulating cytokines and genetic alterations, such as JAK(V617F ...
Fuentes-Mattei E +29 more
europepmc +8 more sources
MiR-543 Promotes Migration, Invasion and Epithelial-Mesenchymal Transition of Esophageal Cancer Cells by Targeting Phospholipase A2 Group IVA [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: The aim of this study was to investigate the roles of miR-543 and phospholipase A2 group IVA (PLA2G4A) in cell mobility and the invasiveness cascade in esophageal squamous cell carcinoma (ESCC) and to validate the interactive ...
Huaying Zhao +7 more
doaj +2 more sources
ZNF281-miR-543 Feedback Loop Regulates Transforming Growth Factor-β-Induced Breast Cancer Metastasis [PDF]
Molecular Therapy: Nucleic Acids, 2020 Breast cancer is the most common malignancy, and metastasis is the main cause of cancer-associated mortality in women worldwide. Transforming growth factor-β (TGF-β) signaling, an inducer of epithelial-to-mesenchymal transition (EMT), plays an important ...
Wei Ji +4 more
doaj +2 more sources