Results 21 to 30 of about 215,132 (245)

LINC‐PINT alleviates lung cancer progression via sponging miR‐543 and inducing PTEN [PDF]

Cancer Medicine, 2020
Long intergenic nonprotein coding RNA p53‐induced transcript (LINC‐PINT) has been reported to participate in various cancers. Here, we investigated the effects of LINC‐PINT on lung cancer progression.
Shu Wang, Wenyang Jiang, Xinghua Zhang, Zilong Lu, Qing Geng, Wei Wang, Nan Li, Xinyong Cai   +7 more
doaj   +5 more sources

Placental Growth Factor Promotes Metastases of Ovarian Cancer Through MiR-543-Regulated MMP7

Cellular Physiology and Biochemistry, 2015
Background/Aims: Elucidation of the molecular mechanisms underlying ovarian cancer (OC) cell invasion and migration may provide important evidence for developing efficient therapy.
Ning Song, Hao Liu, Xiaoxin Ma, Shulan Zhang   +3 more
doaj   +4 more sources

Higher miR‐543 levels correlate with lower STK31 expression and longer pancreatic cancer survival [PDF]

Cancer Medicine, 2020
AbstractPancreatic cancer (PC) is one of the most malignant gastrointestinal tumors and the 5‐year survival is only 9%. The expression of miRNAs in serum has been proved to be related to tumorigenesis and development of cancers. The miRNA targets and gene targets were predicted in microRNA.org, miRDB, TargetScan, and RNAInter.
Weizhong Yuan, Guangfu Wang
exaly   +5 more sources

Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3. [PDF]

PLoS ONE, 2018
Molecular chaperones are important regulators of protein folding and proteasomal removal of misfolded proteins. In spinocerebellar ataxia type 3 (SCA3), the co-chaperone DnaJ homology subfamily B member 1 (DNAJB1 or heat shock protein 40) is recruited to
Bernd O Evert, Rohit Nalavade, Johannes Jungverdorben, Frank Matthes, Stephanie Weber, Ashish Rajput, Stefan Bonn, Oliver Brüstle, Michael Peitz, Sybille Krauß   +9 more
doaj   +4 more sources

CTGF promotes osteosarcoma angiogenesis by regulating miR-543/angiopoietin 2 signaling

Cancer Letters, 2017
Osteosarcoma is the most common primary solid tumor of bone. It has a high metastatic potential and occurs predominantly in adolescents and young adults. Angiopoietin 2 (Angpt2) is a key regulator in tumor angiogenesis, facilitating tumor growth and metastasis.
Li-Hong Wang, Chih-Yang Lin, Yuan-Li Huang   +2 more
exaly   +4 more sources

MiR-543 Promotes Migration, Invasion and Epithelial-Mesenchymal Transition of Esophageal Cancer Cells by Targeting Phospholipase A2 Group IVA [PDF]

Cellular Physiology and Biochemistry, 2018
Background/Aims: The aim of this study was to investigate the roles of miR-543 and phospholipase A2 group IVA (PLA2G4A) in cell mobility and the invasiveness cascade in esophageal squamous cell carcinoma (ESCC) and to validate the interactive ...
Huaying Zhao, Changying Diao, Xiaohui Wang, Yilin Xie, Yaqing Liu, Xianzheng Gao, Jing Han, Shenglei Li   +7 more
doaj   +2 more sources

m5C modification of LINC01082 inhibits osteosarcoma progression by modulating the miR-543-TNRC6A axis. [PDF]

Transl Oncol
Osteosarcoma (OS) is a highly malignant bone tumor primarily affecting children and adolescents, with a significant portion of patients developing metastasis, leading to poor prognosis. Recent studies have identified long noncoding RNAs (lncRNAs) as critical regulators in cancer progression.
Hu Y, Wu J, Zeng H, Zhou J, Gong M, Guo Z, Zhang W, Zhang N, Zhang H.   +8 more
europepmc   +4 more sources

miR‑543 acts as a novel oncogene in oral squamous cell carcinoma by targeting CYP3A5. [PDF]

Oncol Rep, 2019
MicroRNAs (miRNAs/miRs) are small non‑coding RNAs that can act as oncogenes or tumor‑suppressor genes in human cancer. Previous studies have revealed that abnormal expression of miRNAs is closely associated with tumor cell cycle, differentiation, growth and apoptosis.
Wang L, Chen W, Zha J, Yan Y, Wei Y, Chen X, Zhu X, Ge L.   +7 more
europepmc   +4 more sources

miR-543 Inhibits the Occurrence and Development of Intrauterine Adhesion by Inhibiting the Proliferation, Migration, and Invasion of Endometrial Cells. [PDF]

Biomed Res Int, 2021
Objective. To explore the function of miR‐543 in endometrial cells and the possible mechanism of regulating the occurrence and development of intrauterine adhesion. Method. Endometrial epithelial cells and endometrial adenocarcinoma cells were transfected with miR‐543 mimics and miR‐543 inhibitor as the experimental group and were tested with the ...
Liu X, Xu Q, Chen C, Duan H.
europepmc   +4 more sources

miR-543 functions as a tumor suppressor in glioma in vitro and in vivo. [PDF]

Oncol Rep, 2017
Gliomas are the most common primary central nervous system tumors and account for approximately 80% of malignant brain tumors. MicroRNAs (miRNAs) are a class of small non-coding, regulatory RNA molecules that mediate the expression levels of specific proteins.
Xu L, Yu J, Wang Z, Zhu Q, Wang W, Lan Q.   +5 more
europepmc   +4 more sources