Results 41 to 50 of about 215,132 (245)
Design of crRNA to Regulate MicroRNAs Related to Metastasis in Colorectal Cancer Using CRISPR-C2c2 (Cas13a) Technique [PDF]
Cell Journal, 2023 Colorectal cancer (CRC) is the third most prevalent cancer with the second-highest mortality rate worldwide. microRNAs(miRNAs) of cancer-derived exosomes have shown promising diagnosis potential.
Seyed Taleb Houseini +4 more
doaj +1 more source
Endometrial MIR-543 is down-regulated during the implantation window in women with endometriosis-related infertility [PDF]
Fertility and Sterility, 2018 Differentially expressed microRNAs (miRNAs) and their target mRNAs may lead to alterations in normal physiological status of the tissues and initiate pathological processes. The aim of this study was to investigate the expression of the most relevant miRNAs in the eutopic endometrial tissue during the window of implantation in women with endometriosis ...
Puyu, Yang +5 more
openaire +2 more sources
Cell Death and Disease, 2021 Aberrant microRNA (miR) expression plays an important role in pathogenesis of different types of cancers, including B-cell lymphoid malignancies and in the development of chemo-sensitivity or -resistance in chronic lymphocytic leukemia (CLL) as well as ...
Isha Kapoor +3 more
doaj +1 more source
MiR-543 inhibits proliferation and metastasis of human colorectal cancer cells by targeting PLAS3.
European review for medical and pharmacological sciences, 2020 Colorectal cancer (CRC) has a very high morbidity and mortality worldwide. Related studies have shown that microRNA-543 (miR-543) is involved in the development of many cancers, including CRC. The purpose of this study was to explore the potential molecular mechanism of miR-543's involvement in the development of CRC.QRT-PCR and Western blot were used ...
Su, D.-W. +5 more
openaire +2 more sources
miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]
, 2012 Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Cuppen, E. +41 more
core +1 more source
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the mechanism of lncRNA MEG3 (MEG3) modulating the proliferation and metastasis of pancreatic cancer cells via regulating miR-543/PTEN axis.
CHENG Jianxiao +4 more
doaj +1 more source
MiR-370 and miR-543 regulate endogenous DNAJB1.
, 2018 (A) A pool of miR-370 and miR-543 mimics was transfected into Hela cells and DNAJB1 protein was detected on a western blot using DNAJB1 specific antibodies. GAPDH was detected as loading control. A representative blot of an n = 4 is shown. p = 0.0439 (B)
Bernd O. Evert (5608034) +9 more
core +1 more source
A review on the role of MCM3AP-AS1 in the carcinogenesis and tumor progression
Cancer Cell International, 2022 Minichromosome Maintenance Complex Component 3 Associated Protein Antisense 1 (MCM3AP-AS1) is an RNA gene located on 21q22.3. The sense transcript from this locus has dual roles in the pathogenesis of solid tumors and hematological malignancies.
Soudeh Ghafouri-Fard +4 more
doaj +1 more source
MiR-543-5p targets the 3’ UTR of Gh1 mRNA.
, 2019 (A) Identification of miRNAs which may target the Gh1 3’UTR. Changes of relative luciferase activity of the pmiR- Gh1-3’UTR-WT vector after the 5 candidate miRNAs were transfected into 293T cells.
Hai-Xiang Guo (7372586) +9 more
core +1 more source
miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity [PDF]
, 2013 miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small non-coding gene, which have been suggested to play roles in both immune and neuronal function.
Mistry, Rajen B. +40 more
core +1 more source