Results 41 to 50 of about 2,122,830 (164)

Cooperative miRNA-dependent PTEN regulation drives resistance to BTK inhibition in B-cell lymphoid malignancies

open access: yesCell Death and Disease, 2021
Aberrant microRNA (miR) expression plays an important role in pathogenesis of different types of cancers, including B-cell lymphoid malignancies and in the development of chemo-sensitivity or -resistance in chronic lymphocytic leukemia (CLL) as well as ...
Isha Kapoor   +3 more
doaj   +1 more source

MiR-543 inhibits proliferation and metastasis of human colorectal cancer cells by targeting PLAS3.

open access: yesEuropean review for medical and pharmacological sciences, 2020
Colorectal cancer (CRC) has a very high morbidity and mortality worldwide. Related studies have shown that microRNA-543 (miR-543) is involved in the development of many cancers, including CRC. The purpose of this study was to explore the potential molecular mechanism of miR-543's involvement in the development of CRC.QRT-PCR and Western blot were used ...
Su, D.-W.   +5 more
openaire   +2 more sources

Additional file 1 of miR-543 regulates high glucose-induced fibrosis and autophagy in diabetic nephropathy by targeting TSPAN8

open access: yes, 2022
Additional file 1: Supplementary Figure S1. RNA FISH analysis of miR-543 expression in kidney cortex and medulla.
Xiaoyan Pei (201100)   +5 more
core   +1 more source

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]

open access: yes, 2014
Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA   +13 more
core   +1 more source

MiR-370 and miR-543 regulate endogenous DNAJB1.

open access: yes, 2018
(A) A pool of miR-370 and miR-543 mimics was transfected into Hela cells and DNAJB1 protein was detected on a western blot using DNAJB1 specific antibodies. GAPDH was detected as loading control. A representative blot of an n = 4 is shown. p = 0.0439 (B)
Bernd O. Evert (5608034)   +9 more
core   +1 more source

The effect of transfection of miR-543-5p on GH3 cell line and rat pituitary cells.

open access: yes, 2019
(A/E) Analysis of miR-543-5p levels detected by q-PCR after transfection with miR-543a-5p mimic/inhibitor in GH3 cells. (I/M) Analysis of miR-543-5p levels detected by q-PCR after transfection with miR-543a-5p mimic/inhibitor in rat anterior pituitary ...
Hai-Xiang Guo (7372586)   +9 more
core   +1 more source

LncRNA MEG3 Suppresses Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating miR-543/PTEN Axis

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the mechanism of lncRNA MEG3 (MEG3) modulating the proliferation and metastasis of pancreatic cancer cells via regulating miR-543/PTEN axis.
CHENG Jianxiao   +4 more
doaj   +1 more source

A review on the role of MCM3AP-AS1 in the carcinogenesis and tumor progression

open access: yesCancer Cell International, 2022
Minichromosome Maintenance Complex Component 3 Associated Protein Antisense 1 (MCM3AP-AS1) is an RNA gene located on 21q22.3. The sense transcript from this locus has dual roles in the pathogenesis of solid tumors and hematological malignancies.
Soudeh Ghafouri-Fard   +4 more
doaj   +1 more source

MiR-543-5p targets the 3’ UTR of Gh1 mRNA.

open access: yes, 2019
(A) Identification of miRNAs which may target the Gh1 3’UTR. Changes of relative luciferase activity of the pmiR- Gh1-3’UTR-WT vector after the 5 candidate miRNAs were transfected into 293T cells.
Hai-Xiang Guo (7372586)   +9 more
core   +1 more source

Arginine Supply Impacts the Expression of Candidate microRNA Controlling Milk Casein Yield in Bovine Mammary Tissue

open access: yesAnimals, 2020
Arginine, a semi-essential functional amino acid, has been found to promote the synthesis of casein in mammary epithelial cells to some extent. Data from mouse indicated that microRNA (miRNA) are important in regulating the development of mammary gland ...
Xin Zhang   +7 more
doaj   +1 more source

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