Results 41 to 50 of about 5,727 (227)
Cell Death and Disease, 2021 Aberrant microRNA (miR) expression plays an important role in pathogenesis of different types of cancers, including B-cell lymphoid malignancies and in the development of chemo-sensitivity or -resistance in chronic lymphocytic leukemia (CLL) as well as ...
Isha Kapoor +3 more
doaj +1 more source
CTGF promotes osteosarcoma angiogenesis by regulating miR-543/angiopoietin 2 signaling
Cancer Letters, 2017 Osteosarcoma is the most common primary solid tumor of bone. It has a high metastatic potential and occurs predominantly in adolescents and young adults. Angiopoietin 2 (Angpt2) is a key regulator in tumor angiogenesis, facilitating tumor growth and metastasis.
Wang, Li-Hong +9 more
openaire +2 more sources
MiR-543 inhibits proliferation and metastasis of human colorectal cancer cells by targeting PLAS3.
European review for medical and pharmacological sciences, 2020 Colorectal cancer (CRC) has a very high morbidity and mortality worldwide. Related studies have shown that microRNA-543 (miR-543) is involved in the development of many cancers, including CRC. The purpose of this study was to explore the potential molecular mechanism of miR-543's involvement in the development of CRC.QRT-PCR and Western blot were used ...
Su, D.-W. +5 more
openaire +2 more sources
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the mechanism of lncRNA MEG3 (MEG3) modulating the proliferation and metastasis of pancreatic cancer cells via regulating miR-543/PTEN axis.
CHENG Jianxiao +4 more
doaj +1 more source
A review on the role of MCM3AP-AS1 in the carcinogenesis and tumor progression
Cancer Cell International, 2022 Minichromosome Maintenance Complex Component 3 Associated Protein Antisense 1 (MCM3AP-AS1) is an RNA gene located on 21q22.3. The sense transcript from this locus has dual roles in the pathogenesis of solid tumors and hematological malignancies.
Soudeh Ghafouri-Fard +4 more
doaj +1 more source
Animals, 2020 Arginine, a semi-essential functional amino acid, has been found to promote the synthesis of casein in mammary epithelial cells to some extent. Data from mouse indicated that microRNA (miRNA) are important in regulating the development of mammary gland ...
Xin Zhang +7 more
doaj +1 more source
Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto
Jurnal Kesehatan Andalas, 2021 Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih +2 more
doaj +1 more source
MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable Shock. [PDF]
PLoS ONE, 2016 Depression is a highly heterogeneous disorder presumably caused by a combination of several factors ultimately causing the pathological condition. The genetic liability model of depression is likely to be of polygenic heterogeneity.
Katrine Svenningsen +8 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Accurate spinal tuberculosis (TB) diagnosis is of utmost importance for adequately treating and managing the disease. Given the need for additional diagnostic tools, this study aimed to investigate the utility of host serum miRNA biomarkers for ...
Qiang Liang +10 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source