Results 61 to 70 of about 215,132 (245)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. [PDF]

open access: yesPLoS ONE, 2015
Hypertrophic scarring is a frequent fibroproliferative complication following deep dermal burns leading to impaired function and lifelong disfigurement. Decorin reduces fibrosis and induces regeneration in many tissues, and is significantly downregulated
Peter Kwan, Jie Ding, Edward E Tredget
doaj   +1 more source

The effects of overexpressing or inhibiting miR-543-5p on the expression level of Gh1 and the secretion level of GH in GH3 cell line and in rat anterior pituitary.

open access: yes, 2019
Gh1 relative expression (A) and GH concentration (B) after transfection with siRNA in GH3 cell line. (C-D) Analysis of Gh1 levels detected by q-PCR in miR-543-5p nc, mimic, i-nc, and inhibitor groups in GH3 cell line.
Hai-Xiang Guo (7372586)   +9 more
core   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]

open access: yes, 2012
Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Oak, Prajakta S.   +11 more
core   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee   +7 more
wiley   +1 more source

Integration of Low‐Voltage Nanoscale MoS2 Memristors on CMOS Microchips

open access: yesAdvanced Functional Materials, EarlyView.
This article presents the first monolithic integration of nanoscale MoS2‐based memristors into the back‐end‐of‐line of foundry‐fabricated CMOS microchips in a one‐transistor‐one‐resistor (1T1R) architecture. The MoS2‐based 1T1R cells exhibit forming‐free, nonvolatile resistive switching with ultra‐low operating voltages, low cycle‐to‐cycle variability ...
Jimin Lee   +16 more
wiley   +1 more source

The roles of ING5 in cancer: A tumor suppressor

open access: yesFrontiers in Cell and Developmental Biology, 2022
As a Class II tumor suppressor, ING5 contains nuclear localization signal, plant homeodomain, novel conserved region, and leucine zipper-like domains. ING5 proteins form homodimer into a coil-coil structure, and heterodimers with ING4, histone H3K4me3 ...
Hua-chuan Zheng, Hang Xue, Hua-mao Jiang
doaj   +1 more source

Advances in Magnesium‐Based Thermoelectrics: A Critical Review

open access: yesAdvanced Materials, EarlyView.
Magnesium‐based thermoelectric materials have emerged as promising candidates for low‐to‐mid‐temperature energy conversion due to their abundance, low cost, and competitive performance. This review summarizes recent advances in Mg3X2, MgAgSb, and Mg2X systems, covering transport mechanisms, fabrication strategies, stability challenges, and device ...
Li‐Min Zhang   +5 more
wiley   +1 more source

Three‐Dimensional Printed Microarchitected Hierarchically Porous Biodegradable PLA/S/CNT Nanocomposite Electrodes for High‐Performance Lithium–Sulfur Batteries

open access: yesAdvanced Materials Technologies, EarlyView.
Hierarchically microarchitected PLA/S/CNT cathodes are fabricated via scalable fused filament 3D printing as high‐sulfur‐loading hosts for rechargeable lithium–sulfur batteries. The assembled Li–S cells with sulfur loadings up to 17 mg cm−2 deliver an areal capacity of 9.2 mAh cm−2 and retain 96% of their discharge capacity after 100 charge–discharge ...
Vinay Gupta   +4 more
wiley   +1 more source

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