Results 61 to 70 of about 2,122,830 (164)

The roles of ING5 in cancer: A tumor suppressor

Frontiers in Cell and Developmental Biology, 2022
As a Class II tumor suppressor, ING5 contains nuclear localization signal, plant homeodomain, novel conserved region, and leucine zipper-like domains. ING5 proteins form homodimer into a coil-coil structure, and heterodimers with ING4, histone H3K4me3 ...
Hua-chuan Zheng, Hang Xue, Hua-mao Jiang
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The effects of overexpressing or inhibiting miR-543-5p on the expression level of Gh1 and the secretion level of GH in GH3 cell line and in rat anterior pituitary.

, 2019
Gh1 relative expression (A) and GH concentration (B) after transfection with siRNA in GH3 cell line. (C-D) Analysis of Gh1 levels detected by q-PCR in miR-543-5p nc, mimic, i-nc, and inhibitor groups in GH3 cell line.
Hai-Xiang Guo (7372586), Ze-Wen Yu (7372580), Jin-Yu Zhang (4336489), Wei Gao (2085), Chang-Jiang Wang (4956223), Bao Yuan (585607), Jin-Ping Hu (3138867), Wen-Zhi Ren (4336492), Xin-Yao Feng (7372583), Jian Chen (15340)   +9 more
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miR-105 and miR-767 expression across cell lines.

, 2022
(A) miR-105 and (B) miR-767 expression levels were measured across 13 cell lines. (C) Expression was consistent with patient data, as miR-105 and miR-767 expression were highly correlated.
Guanying Bianca Xu (12700306), Laura Moody (4054255), Yuan-Xiang Pan (9369757), Hong Chen (108084)   +3 more
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miR-543 inhibits tumor malignant progression by regulating TWIST1 in human gastric cancer [PDF]

, 2020
Abstract Background: TWIST1, a highly conserved basic helix-loop-helix (bHLH) transcription factor, is essential to epithelial-mesenchymal transition (EMT) and cancer metastasis in gastric cancer (GC). However, little is known about the post-transcriptional regulation of TWIST1, especially the mechanisms involving microRNAs.
Guoda Lian, Xuanna Li, Shaojie Chen, Jiajia Li, Yaqing Li, Shangxiang Chen, Xiangan Lin, Haoming Lin, Kaihong Huang, Yinting Chen   +9 more
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HSV1 infection induces expression of the AOPEP-miR-23b/ miR-27b/ miR-24-1 locus.

, 2021
(A) (B) STING expression was analyzed by western blotting in human (A) HT1080 cells and (B) mouse NB41A3 cells upon HSV1 infection (MOI-5). (C) Figure depicting expression of miR-24 from 2 genetic loci.
Chenyao Wang (659588), Ganes C. Sen (9708002), Nikhil Sharma (571073), Patricia Kessler (11506500)   +3 more
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Identification of a novel necroptosis-associated miRNA signature for predicting the prognosis in head and neck squamous cell carcinoma

Open Medicine, 2022
Head and neck squamous cell carcinoma (HNSCC) is one of the most aggressive malignancies that have a poor prognosis. Necroptosis has been demonstrated in recent years to be a form of inflammatory cell death occurring in multicellular organism, which ...
Guan Jiezhong, Liu Xinyu, Wang Kang, Jia Yiqun, Yang Bo   +4 more
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Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

Nature Communications, 2021
SMAD4 is mutated in human lung cancer, but the underlying mechanism by which Smad4 loss-of-function (LOF) accelerates lung cancer metastasis is yet to be elucidated.
Xiaohong Tan, Lu Tong, Lin Li, Jinjin Xu, Shaofang Xie, Lei Ji, Junjiang Fu, Qingwu Liu, Shihui Shen, Yun Liu, Yanhui Xiao, Feiran Gao, Robb E. Moses, Nabeel Bardeesy, Yanxiao Wang, Jishuai Zhang, Longying Tang, Lei Li, Kwok-kin Wong, Dianwen Song, Xiao Yang, Jian Liu, Xiaotao Li   +22 more
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The miR-590 C57T SNP reduces levels of miR-590-5p and miR-590-3p, without affecting the levels of pri-miR-590 and pre-miR-590.

, 2016
(A) Quantification of pri-miR-590 by qRT-PCR normalized by GAPDH. Mean ± SD (n = 3). HEK293T cells were transfected with the pri-miR-590-WT or pri-miR-590-SNP plasmids. The empty plasmid was used as negative control.
Suresh K. Kandasamy (2794198), Steven Steinberg (582816), Scot J. Matkovich (421129), Neal Epstein (2794180), Dotti Tripodi (2794204), Garry Cutting (2794201), Xiaoping Lin (215407), Blaid Mbiyangandu (2794195), Celia P. Corona-Villalobos (2794189), Ryuya Fukunaga (2794186), M. Roselle Abraham (242563), Junaid Afzal (2794192), Susan E. Liao (2794177), Yufan Guan (2794171), Zhaoxia Huo (2794183), Theodore P. Abraham (2794174)   +15 more
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LncRNA GATA6-AS1 Inhibits the Progression of Non-Small Cell Lung Cancer via Repressing microRNA-543 to Up-Regulating RKIP [Expression of Concern]

Cancer Management and Research, 2021
Gong Z, Chen X, Zhang Y, et al. Cancer Manag Res. 2020;12:9327–9338. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article.
Gong Z, Chen X, Zhang Y, Liu C, Wang Z, Xu X, Zhu J, Xue T   +7 more
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Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo. [PDF]

, 2012
Cytomegaloviruses express large amounts of viral miRNAs during lytic infection, yet, they only modestly alter the cellular miRNA profile. The most prominent alteration upon lytic murine cytomegalovirus (MCMV) infection is the rapid degradation of the ...
Lisnić, V. (V) J. (J), Marcinowski, Lisa, Tanguy, M. (M), Ruzsics, Zsolt, Tanguy Mélanie, Ralf Zimmer, Jonjic, S. (S), Erhard, F. (F), Krmpotic Astrid, Marina Babic (184917), Corinna Benkartek, Bernd Rädle (138968), Zsolt Ruzsics, Babic, Marina, Ruzsics, Z. (Zsolt), Jonjic Stipan, Trgovcich, Joanne, Erhard, Florian, Chane-woon-ming, B. (Béatrice), Tanguy, Mélanie, Chane-Woon-Ming Béatrice, Koszinowski, U. (Ulrich H), Marcinowski Lisa, Marina Babic, Ulrich H Koszinowski, Koszinowski Ulrich H., Joanne Trgovcich (184921), Astrid Krmpotic (184892), Stipan Jonjic (139671), Stipan Jonjic, Babic Marina, Vanda J. Lisnić (184897), Krmpotic, A. (A), Sébastien Pfeffer, Benkartek Corinna, Zsolt Ruzsics (75383), Béatrice Chane-Woon-Ming (184904), Zimmer Ralf, Lisa Marcinowski (138962), Marcinowski, L. (L), Marcinowski, L. (Lisa), Krmpotic, Astrid, Dölken, Lars, Béatrice Chane-Woon-Ming, Joanne Trgovcich, Rädle Bernd, Trgovcich, J. (Joanne), Rädle, B. (Bernd), Lars Dölken, Astrid Krmpotic, Florian Erhard (184910), Lars Dölken (138985), Babic, M. (M), Jonjic, S. (Stipan), Ulrich H. Koszinowski (152143), Lisnić, Vanda J., Lisnić, V. (Vanda J), Trgovcich Joanne, Benkartek, Corinna, Zimmer, Ralf, Erhard Florian, Dölken Lars, Ruzsics, Z. (Z), Ralf Zimmer (21157), Rädle, B. (B), Dölken, L. (L), Vanda J Lisnić, Tuddenham, L. (Lee), Trgovcich, J. (J), Lisnić Vanda J., Lee Tuddenham (141455), Pfeffer, S. (Sebastien), Rädle, Bernd, Corinna Benkartek (184913), Lisa Marcinowski, Zimmer, R. (Ralf), Tuddenham Lee, Benkartek, C. (C), Lee Tuddenham, Erhard, F. (Florian), Pfeffer Sébastien, Babic, M. (Marina), Tuddenham, Lee, Mélanie Tanguy (4691986), Mélanie Tanguy, Florian Erhard, Koszinowski, U. (U) H. (H), Ruzsics Zsolt, Krmpotic, A. (Astrid), Koszinowski, Ulrich H., Tanguy, M. (Mélanie), Dölken, L. (Lars), Zimmer, R. (R), Chane-Woon-Ming, Béatrice, Bernd Rädle, Sébastien Pfeffer (8264), Pfeffer, Sébastien, Benkartek, C. (Corinna), Jonjic, Stipan, Lisnić, Vanda, J, Koszinowski, Ulrich, H   +100 more
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