Results 21 to 30 of about 255,804 (230)

A Review on the Carcinogenic Roles of DSCAM-AS1

open access: yesFrontiers in Cell and Developmental Biology, 2021
Long non-coding RNAs (lncRNAs) are a group of transcripts with fundamental roles in the carcinogenesis. DSCAM Antisense RNA 1 (DSCAM−AS1) is an example of this group of transcripts which has been firstly identified in an attempt to find differentially ...
Soudeh Ghafouri-Fard   +3 more
doaj   +1 more source

LINC01094 Upregulates LIN28B Expression by Sponging miR-577 to Promote Pancreatic Cancer Proliferation and Metastasis [PDF]

open access: yes, 2021
Abstract Backgroud: The leading cause of death in pancreatic cancer (PC) patients is the progression of cancer metastasis. Long non-coding RNAs (lncRNAs) play an important role in regulating cancers, however its molecular basis in pancreatic cancer (PC) remains to be explored.Methods: In this study, bioinformatics methods are used to predict ...
Chen Luo   +5 more
openaire   +1 more source

A microRNA panel that regulates proinflammatory cytokines as diagnostic and prognosis biomarkers in colon cancer

open access: yesBiochemistry and Biophysics Reports, 2022
Colon cancer (CC) is the third most common neoplasm and the fourth cause of cancer-related death worldwide in both sexes. It has been established that inflammation plays a critical role in tumorigenesis and progression of CC.
Antonio Martínez-Gutierrez   +10 more
doaj   +1 more source

Circulating miRNAs in Serum as Biomarkers for Early Diagnosis of Non-small Cell Lung Cancer

open access: yesFrontiers in Genetics, 2021
BackgroundNon-small cell lung cancer (NSCLC) accounts for about 85% of lung cancers. This study aimed to discover the potential miRNA biomarkers for early detection of NSCLC.MethodsTotal circulating miRNAs were extracted from six patients and six ...
Xiaotong Duan   +6 more
doaj   +1 more source

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]

open access: yes, 2014
Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA   +13 more
core   +1 more source

Long noncoding RNA MIR99AHG promotes gastric cancer progression by inducing EMT and inhibiting apoptosis via miR577/FOXP1 axis

open access: yesCancer Cell International, 2020
Background Long non-coding RNAs (lncRNAs) play a vital role in the genesis and development of human cancer. LncRNA MIR99AHG has been reported to be upregulated in acute myeloid leukemia (AML); however, its function in gastric cancer (GC) is still not ...
Qingyang Meng   +5 more
doaj   +1 more source

miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]

open access: yes, 2012
Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Cuppen, E.   +52 more
core   +2 more sources

Additional file 1 of LncRNA NORAD facilitates oral squamous cell carcinoma progression by sponging miR-577 to enhance TPM4

open access: yes, 2022
Additional file 1: Figure S1. (A) The expression of TPM4 and miR-577 in OSCC tissues and normal adjacent tissue was detected. (B) The expression of NORAD, miR-577 and TPM4 in OSCC tissues were extracted from online TCGA-HNSC datasets was presented. **P 
Jianwei Liu (163716)   +5 more
core   +1 more source

Integrated bioinformatic analysis of dysregulated microRNA‐mRNA co‐expression network in ovarian endometriosis

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2022
Introduction Ovarian endometriosis is a frequently occurring gynecological disease with large socioeconomic impact. Accumulating evidence has suggested that aberrant miRNA‐mRNA interactions are involved in the pathogenesis and progression of ovarian ...
Yong Liu   +10 more
doaj   +1 more source

miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity [PDF]

open access: yes, 2013
miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small non-coding gene, which have been suggested to play roles in both immune and neuronal function.
Mistry, Rajen B.   +40 more
core   +1 more source

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