Results 31 to 40 of about 255,804 (230)

FGD5‑AS1 is an oncogenic lncRNA in pancreatic cancer and regulates the Wnt/β‑catenin signaling pathway via miR‑577

Oncology Reports, 2021
The objective of the present study was to clarify the expression characteristics of long non‑coding RNA (lncRNA) FGD5 antisense RNA 1 (FGD5‑AS1) in pancreatic cancer, as well as its biological function and underlying mechanism. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) was utilized for the detection of FGD5‑AS1 and microRNA
Zhang, Wei-Tao, Zhang, Ji-Jun, Shao, Quan, Wang, Ying-Kai, Jia, Jie-Peng, Qian, Bo, Tian, Xiao-Wen, Yan, Wen-Ji   +7 more
openaire   +3 more sources

MiR‐577 suppresses epithelial‐mesenchymal transition and metastasis of breast cancer by targeting Rab25

Thoracic Cancer, 2018
BackgroundMicroRNAs can act as both tumor suppressor genes and oncogenes and participate in cell proliferation, metastasis, and apoptosis. Low levels of miR‐577 are found in several cancers, for example, thyroid carcinoma, glioblastoma, and hepatocellular carcinoma.
Chonggao Yin, Qingjie Mou, Xinting Pan, Guoxin Zhang, Hongli Li, Yunbo Sun   +5 more
openaire   +2 more sources

Bioinformatics Analysis of the Mechanisms of Diabetic Nephropathy via Novel Biomarkers and Competing Endogenous RNA Network

Frontiers in Endocrinology, 2022
Diabetic nephropathy (DN) is one of the common chronic complications of diabetes with unclear molecular mechanisms, which is associated with end-stage renal disease (ESRD) and chronic kidney disease (CKD).
Mingfei Guo, Yaji Dai, Lei Jiang, Jiarong Gao   +3 more
doaj   +1 more source

Importancia clínica de los micrornas de la vía de p53 en cáncer de pulmón no microcítico: miR-34a y miR-16 [PDF]

, 2011
[spa] El cáncer de pulmón no célula pequeña es la neoplasia más frecuente en la actualidad en los países industrializados, siendo la primera causa de mortalidad por cáncer en el varón. Su incidencia continúa aumentando progresivamente, y su tratamiento,
Gallardo Martín, Elena
core   +6 more sources

Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma

Clinical and Translational Medicine, 2023
Background The incidence of renal cell carcinoma (RCC) has increased in recent years. Metastatic RCC is common and remains a major cause of mortality.
Junjie Cen, Yanping Liang, Zihao Feng, Xu Chen, Jinlong Chen, Yinghan Wang, Jiangquan Zhu, Quanhui Xu, Guannan Shu, Wenbin Zheng, Hui Liang, Zhu Wang, Qiong Deng, Jiazheng Cao, Junhang Luo, Xiaohan Jin, Yong Huang   +16 more
doaj   +1 more source

Oncogenic role and potential regulatory mechanism of fatty acid binding protein 5 based on a pan-cancer analysis

Scientific Reports, 2023
As one member of fatty acid binding proteins (FABPs), FABP5 makes a contribution in the occurrence and development of several tumor types, but existing analysis about FABP5 and FABP5-related molecular mechanism remains limited.
Jinhua Wang, Siqi Zhao, Jian Sun, Xiaobo Wang, Mingze Guan, Jiajun Yin, Bo Tang   +6 more
doaj   +1 more source

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]

, 2012
Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Oak, Prajakta S., Prajakta S. Oak (115995), Florian Kopp, Andreas Roidl, Kopp, Florian, Roidl, Andreas, Prajakta S Oak, Florian Kopp (115988), Ernst Wagner (60760), Andreas Roidl (116002), Wagner, Ernst, Ernst Wagner   +11 more
core   +2 more sources

miR449_string_hires_image-5-miR-449-miR-34.png

, 2023
miR449_string_hires_image-5-miR-449-miR-34 ...
Federica Monaco (17674014)
core   +1 more source

LncRNA DANCR Restrains Sensitivity to 5-fluorouracil in Prostate Cancer through Sponging MiR-577

INTERNATIONAL JOURNAL OF HUMAN GENETICS, 2021
ABSTRACT This present study explored the functions of lncRNA DANCR on regulating sensitivity to 5-fluorouracil (5- FU) in prostate cancer in vitro. The RT-qPCR examined RNA expressions of LNCRNA DANCR in RWPE-1, VCaP, PC3 and LNCaP cells, which also measured RNA levels of miR-577 in PC3 cells. DANCR was highly expressed in prostate cancer cell lines. 5-
openaire   +1 more source

Bioinformatics analysis of hedgehog interacting protein in colorectal cancer: a study based on GEO data and TCGA data

BMC Gastroenterology, 2023
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Hedgehog Interacting Protein (HHIP) is evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes,However, the specific role ...
Fengyihuan Fu, Yuan Zhang, Jubin Feng, Yuqiang Nie   +3 more
doaj   +1 more source