Results 11 to 20 of about 190 (178)

Effect of miR‐630 expression on esophageal cancer cell invasion and migration [PDF]

Journal of Clinical Laboratory Analysis, 2021
AbstractBackgroundEsophageal cancer (EC) is a common malignancy of the digestive tract, with high incidence. The objective of this study was to investigate the effect of miR‐630 expression on esophageal cancer (EC) cell invasion and migration.MethodsThe study group comprised 58 EC patients admitted to our hospital from April 2014 to 2016, and the ...
Xi Liu, Wei Wu, Shixin Zhang, Wenfeng Tan, Yang Qiu, Kelong Liao, Kang Yang   +6 more
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miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death [PDF]

Cancer Research, 2010
Abstract MicroRNAs (miRNA) are noncoding RNAs that regulate multiple cellular processes, including proliferation and apoptosis. We used microarray technology to identify miRNAs that were upregulated by non–small cell lung cancer (NSCLC) A549 cells in response to cisplatin (CDDP).
Lorenzo, Galluzzi, Eugenia, Morselli, Ilio, Vitale, Oliver, Kepp, Laura, Senovilla, Alfredo, Criollo, Nicolas, Servant, Caroline, Paccard, Philippe, Hupé, Thomas, Robert, Hugues, Ripoche, Vladimir, Lazar, Annick, Harel-Bellan, Philippe, Dessen, Emmanuel, Barillot, Guido, Kroemer   +15 more
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MiR-630 inhibits invasion and metastasis in esophageal squamous cell carcinoma [PDF]

Acta Biochimica et Biophysica Sinica, 2016
Esophageal squamous cell carcinoma (ESCC) is among the most aggressive malignancies and has a high incidence in China. MicroRNAs (miRNAs) are small endogenous RNAs that regulate multiple tumorigenic processes, including proliferation, invasion, metastasis and prognosis.
Li, Jin, Jun, Yi, Yanping, Gao, Siqi, Han, Zhenyue, He, Longbang, Chen, Haizhu, Song   +6 more
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miR-630 functions as a tumor oncogene in renal cell carcinoma [PDF]

Archives of Medical Science, 2016
MicroRNAs (miRNAs) are non-coding RNAs that regulate multiple cell processes during cancer progression. Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. In this study, we aimed to investigate the roles of miR-630 in RCC progression.Expression of miR-630 was evaluated by quantitative real-time polymerase chain reaction (qRT-PCR) in four
Zhao, Jian-Jun, Chen, Peng-Jie, Duan, Rui-Qin, Li, Ke-Ji, Wang, Yu-Zhong, Li, Yong   +5 more
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Increased microRNA-630 expression in gastric cancer is associated with poor overall survival. [PDF]

PLoS ONE, 2014
MicroRNAs are noncoding RNAs that regulate multiple cellular processes during cancer progression. Among various microRNAs, MiR-630 has recently been identified to be implicated in many critical processes in human malignancies. We aimed to investigate the
Dake Chu, Zhengwei Zhao, Yunming Li, Jipeng Li, Jianyong Zheng, Weizhong Wang, Qingchuan Zhao, Gang Ji   +7 more
doaj   +1 more source

The importance of miRNA-630 in human diseases with an especial focus on cancers

Cancer Cell International, 2022
miR-630 is encoded by MIR630 gene (NC_000015.10) on 15q24.1. This miRNA is mostly associated with cytokine signaling in immune system. Several neoplastic as well as non-neoplastic conditions have been linked with dysregulation of miR-630.
Sepideh Kadkhoda, Soudeh Ghafouri-Fard
doaj   +1 more source

miR-630 Overexpression in Hepatocellular Carcinoma Tissues is Positively Correlated with alpha-Fetoprotein [PDF]

Medical Science Monitor, 2015
MicroRNA-630 (miR-630) has been shown to be involved in various human malignancies. However, its role in hepatocellular carcinoma (HCC) remains unknown.TaqMan qRT-PCR assay was performed to detect the expression of miR-630 in 42 pairs of HCC tissues and corresponding noncancerous hepatocellular tissues, and its correlations with clinicopathologic ...
Zhang, Jian-wen, Li, Yang, Zeng, Xian-Cheng, Zhang, Tong, Fu, Bin-Sheng, Yi, Hui-Min, Zhang, Qi, Jiang, Nan   +7 more
openaire   +2 more sources

Circular RNA CircMTO1 suppressed proliferation and metastasis of osteosarcoma through miR-630/KLF6 axis.

European review for medical and pharmacological sciences, 2021
Circular RNAs (circRNAs) could regulate gene expression which may induce tumor occurrence and progression. In the current study, we first investigated the expression of circMTO1 in osteosarcoma, and the underlying mechanism was further elucidated.Circular RNA microarrays were used to identify the differential expression of circRNAs in osteosarcoma ...
Liu, D.-Y., Li, Z., Zhang, K., Jiao, N., Lu, D.-G., Zhou, D.-W., Meng, Y.-B., Sun, L.   +7 more
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MiR-630 Inhibits Endothelial-Mesenchymal Transition by Targeting Slug in Traumatic Heterotopic Ossification [PDF]

Scientific Reports, 2016
AbstractHeterotopic ossification (HO) is the abnormal formation of mature bone in extraskeletal soft tissues that occurs as a result of inflammation caused by traumatic injury or associated with genetic mutation. Despite extensive research to identify the source of osteogenic progenitors, the cellular origins of HO are controversial and the underlying ...
Yangbai Sun, Jiangyu Cai, Shiyang Yu, Shuai Chen, Fengfeng Li, Cunyi Fan   +5 more
openaire   +2 more sources

Identification and validation of circulating miRNAs as potential new biomarkers for severe liver disease in patients with leptospirosis.

PLoS ONE, 2021
BackgroundLeptospirosis, a global zoonotic infectious disease, has various clinical manifestations ranging from mild self-limiting illness to life-threatening with multi-organ damage, including liver involvement.
Natthaya Chuaypen, Umaporn Limothai, Pattapon Kunadirek, Pornchai Kaewsapsak, Patipark Kueanjinda, Nattachai Srisawat, Pisit Tangkijvanich   +6 more
doaj   +1 more source