Results 31 to 40 of about 214,976 (242)
The importance of miRNA-630 in human diseases with an especial focus on cancers
Cancer Cell International, 2022 miR-630 is encoded by MIR630 gene (NC_000015.10) on 15q24.1. This miRNA is mostly associated with cytokine signaling in immune system. Several neoplastic as well as non-neoplastic conditions have been linked with dysregulation of miR-630.
Sepideh Kadkhoda, Soudeh Ghafouri-Fard
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miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death [PDF]
Cancer Research, 2010 Abstract MicroRNAs (miRNA) are noncoding RNAs that regulate multiple cellular processes, including proliferation and apoptosis. We used microarray technology to identify miRNAs that were upregulated by non–small cell lung cancer (NSCLC) A549 cells in response to cisplatin (CDDP).
Lorenzo, Galluzzi +15 more
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European review for medical and pharmacological sciences, 2021 Circular RNAs (circRNAs) could regulate gene expression which may induce tumor occurrence and progression. In the current study, we first investigated the expression of circMTO1 in osteosarcoma, and the underlying mechanism was further elucidated.Circular RNA microarrays were used to identify the differential expression of circRNAs in osteosarcoma ...
Liu, D.-Y. +7 more
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PLoS ONE, 2021 BackgroundLeptospirosis, a global zoonotic infectious disease, has various clinical manifestations ranging from mild self-limiting illness to life-threatening with multi-organ damage, including liver involvement.
Natthaya Chuaypen +6 more
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The potential of miR-630, an IGF1R regulator, as a predictive biomarker for HER2-targeted drugs. [PDF]
Journal of Clinical Oncology, 2013 620 Background: Innate or acquired resistance to current HER-targeting drugs indicates that their use for HER2-overexpressing breast cancer (BC) treatment may be compromised. miRNAs may have potential as diagnostic, prognostic and predictive biomarkers for treatment response, as well as therapeutic targets and replacement therapies.
Claire Corcoran +5 more
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MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells [PDF]
Cell Death and Disease, 2014 Cao JX +7 more
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Tissue miR-200c-3p and circulating miR-1290 as potential prognostic biomarkers for colorectal cancer
Scientific Reports, 2022 Epithelial–mesenchymal transition (EMT)-related cancers generally elicit low immune responses. EMT is regulated by several microRNAs (miRNAs) in cancers.
Enoch Kang +9 more
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Frontiers in Immunology, 2023 Spondyloarthropathies (SpA) are a family of rheumatic disorders that could be divided into axial (axSpA) and peripheral (perSpA) sub-forms depending on the disease clinical presentation.
Małgorzata Stec +13 more
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Frontiers in Immunology, 2020 IgA nephropathy (IgAN) is the most common primary glomerular disease. The characteristic pathology involves immune complexes formed by the deposition of IgA1 and underglycosylated IgA1 aggregates in the mesangial area, which may be accompanied by the ...
Chan Liu +5 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin +10 more
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