Results 51 to 60 of about 214,976 (242)

MicroRNA expression profiles of whole blood in lung adenocarcinoma. [PDF]

PLoS ONE, 2012
The association of lung cancer with changes in microRNAs in plasma shown in multiple studies suggests a utility for circulating microRNA biomarkers in non-invasive detection of the disease.
Santosh K Patnaik, Sai Yendamuri, Eric Kannisto, John C Kucharczuk, Sunil Singhal, Anil Vachani   +5 more
doaj   +1 more source

Data from miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

, 2023
<div>Abstract<p>MicroRNAs (miRNA) are noncoding RNAs that regulate multiple cellular processes, including proliferation and apoptosis. We used microarray technology to identify miRNAs that were upregulated by non–small cell lung cancer (NSCLC) A549 cells in response to cisplatin (CDDP).
Guido Kroemer, Emmanuel Barillot, Philippe Dessen, Annick Harel-Bellan, Vladimir Lazar, Hugues Ripoche, Thomas Robert, Philippe Hupé, Caroline Paccard, Nicolas Servant, Alfredo Criollo, Laura Senovilla, Oliver Kepp, Ilio Vitale, Eugenia Morselli, Lorenzo Galluzzi   +15 more
openaire   +1 more source

TP53RK and BCL2L2 are direct targets of miR-630.

, 2015
(A) Predicted binding sites of miR-630 in the 3′-UTRs of TP53RK and BCL2L2 (B and C) Fluorescence was significantly reduced in the miR-630 mimics and wild-type dual-luciferase reporter plasmid-transfected group, while it showed no significant change in ...
Guoxin Li (291236), Yan Zhang (8098), Jiefu Wang (782097), Wenhui Ma (427508), Li Yan (107001), Jiang Yu (427506), Hao Liu (12832)   +6 more
core   +1 more source

Dysregulation of circRNA-0076906 and circRNA-0134944 is Correlated with Susceptibility to Osteoporosis and Osteoporotic Fracture in Postmenopausal Females from the Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2023
Weijie Yang,* Wei Zhang,* Fengqian Li, Ning Xu, Ping Sun Department of Orthopedics, Shanghai Eighth People’s Hospital, Shanghai, 200235, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ping Sun ...
Yang W, Zhang W, Li F, Xu N, Sun P
doaj  

Inhibition of miR-630 led to decreased IR sensitivity.

, 2015
(A) Inhibition of miR-630 significantly decreased IR-induced inhibition rate (B and C) Inhibition of miR-630 strongly decreased caspase 3 and caspase 6 activities following IR exposure.
Guoxin Li (291236), Yan Zhang (8098), Jiefu Wang (782097), Wenhui Ma (427508), Li Yan (107001), Jiang Yu (427506), Hao Liu (12832)   +6 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Identification of H2O2 induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataract

BMC Ophthalmology, 2018
Background This study is aimed to screen out the microRNAs (miRNAs) associated with H2O2 induced oxidative stress in human lens epithelial B3 (HLE-B3) cell lines and investigate their relations with the progression of age-related nuclear cataract ...
Song Wang, Chenjun Guo, Mengsi Yu, Xiaona Ning, Bo Yan, Jing Zhao, Angang Yang, Hong Yan   +7 more
doaj   +1 more source

The sensitivity and specificity of serum miR-601 and miR-630 in the diagnosis of icteric leptospirosis, acute liver failure, multiple organ failure and mortality.

, 2021
The sensitivity and specificity of serum miR-601 and miR-630 in the diagnosis of icteric leptospirosis, acute liver failure, multiple organ failure and mortality.
Natthaya Chuaypen (6726911), Nattachai Srisawat (832518), Pattapon Kunadirek (11485833), Pisit Tangkijvanich (513614), Umaporn Limothai (9268591), Patipark Kueanjinda (8278674), Pornchai Kaewsapsak (11485836)   +6 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Differential expression of microRNAs and their messengerRNA targets in men with normal spermatogenesis versus Sertoli cell-only syndrome

Urological Science, 2017
Objective: To identify the profiling of testicular microRNAs (miRNAs) that are differentially expressed in men with normal spermatogenesis versus Sertoli cell-only syndrome (SCOS), to predict the miRNA target genes, and to determine the molecular ...
Yu Sheng Cheng, Chia Ling Chung, Chun Fu Chen, Yung Ming Lin   +3 more
doaj   +1 more source