Results 61 to 70 of about 1,463,889 (197)
Bioinformatic analysis of the ssc-miR-146b upstream promoter region
Sus Scrofa microRNA-146b-5p (ssc-miR-146b) was found to be one of differentially expressional microRNAs (miRNA) in our previous study. Not only it is highly expressed but also it maintains the largest up-regulated differences on the expressional level at
Xin Tao, Xiaoming Men, Ziwei Xu
doaj +1 more source
Background ND630 is believed to be a new therapy pharmacologic molecule in targeting the expression of ACACA and regulating the lipid metabolism. However, the function of ND630 in prostate cancer remains unknown.
Yu-Peng Wu +10 more
doaj +1 more source
A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
TP53RK and BCL2L2 suppress the effects of miR-630 overexpression.
(A) TP53RK or BCL2L2 protein caused a significantly decreased IR-induced inhibition rate in miR-630 transfected cell lines. (B and C) TP53RK or BCL2L2 protein decreased the fold of caspase 3 and caspase 6 activities following IR exposure in miR-630 ...
Guoxin Li (291236) +6 more
core +1 more source
A simple and fast-responsive fluorescent nanoprobe has been developed for fluorescence imaging of miR-630 during apoptosis in A549 cells. This nanoprobe is composed of gold nanoparticles (AuNPs) modified with thiol-terminated DNA hybridized with a TAMRA ...
Yong Jian Jiang +17 more
core +1 more source
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein +3 more
wiley +1 more source
Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen +24 more
wiley +1 more source
MicroRNA-630 (miR-630) has been implicated in the development and progression of multiple cancers. The current study aimed to investigate the role of miR-630 in chemoresistant epithelial ovarian cancer.
어경진 +5 more
core +1 more source
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal +2 more
wiley +1 more source
Kaplan-Meier postoperative survival curve for patterns of patients with gastric cancer and miR-630 expression.
Dake Chu (533975) +7 more
core +1 more source

