Results 41 to 50 of about 1,463,889 (197)

Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression [PDF]

, 2016
MicroRNAs (miRNAs) are small RNA molecules that affect cellular processes by controlling gene expression. Recent studies have shown that hypoxia downregulates Drosha and Dicer, key enzymes in miRNA biogenesis, causing a decreased pool of miRNAs in cancer
Calin, G. A., Previs, R. A., Armaiz-Pena, G. N., McGuire, M., Ivan, C., Yang, D., Pradeep, S., Sood, A. K., Gharpure, K. M., Pecot, C. V., Rodriguez-Aguayo, C., Zhang, W., Bar-Eli, M., Nagaraja, A. S., Rupaimoole, R., Mangala, L. S., Wu, S. Y., Huang, L., Lopez-Berestein, G.   +18 more
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Over-expression of pre-miR-630 reduced IGF-1R expression and inhibited cell growth and induced apoptosis in cells.

, 2013
(A) pre-miR-630 expression in PANC-1 and MiaPaCa-2 cells. (B and C) Increased expression of pre-miR-630 decreased IGF-1R mRNA but not Cdc14A in cells. (D). Decreased IGF-1R protein expression in pre-miR-630 expressed cells.
Arun K. Rishi (141564), Marcia I. Dawson (411957), Jayanta K. Das (411959), Lulu Farhana (411956), Farhan Murshed (411958), Joseph A. Fontana (411960)   +5 more
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Non-Coding Transcriptome Provides Novel Insights into the Escherichia coli F17 Susceptibility of Sheep Lamb

Biology, 2022
It has long been recognized that enterotoxigenic Escherichia coli (ETEC) is the major pathogen responsible for vomiting and diarrhea. E. coli F17, a main subtype of ETEC, is characterized by high morbidity and mortality in young livestock.
Weihao Chen, Xiaoyang Lv, Weibo Zhang, Tingyan Hu, Xiukai Cao, Ziming Ren, Tesfaye Getachew, Joram M. Mwacharo, Aynalem Haile, Wei Sun   +9 more
doaj   +1 more source

TP53RK and BCL2L2 are direct targets of miR-630.

, 2015
(A) Predicted binding sites of miR-630 in the 3′-UTRs of TP53RK and BCL2L2 (B and C) Fluorescence was significantly reduced in the miR-630 mimics and wild-type dual-luciferase reporter plasmid-transfected group, while it showed no significant change in ...
Guoxin Li (291236), Yan Zhang (8098), Jiefu Wang (782097), Wenhui Ma (427508), Li Yan (107001), Jiang Yu (427506), Hao Liu (12832)   +6 more
core   +1 more source

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]

, 2014
Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA, Christiansen, M, Corfield, Valerie A, Christiansen, Kasper M, Carlsen, AL, Christiansen, KM, Carlsen, Anting L, Behr, Elijah R, Kanters, JK, Hedley, Paula L, Kanters, Jørgen K., Christiansen, Michael, Behr, ER, Hedley, PL   +13 more
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MicroRNA expression profiles of whole blood in lung adenocarcinoma. [PDF]

PLoS ONE, 2012
The association of lung cancer with changes in microRNAs in plasma shown in multiple studies suggests a utility for circulating microRNA biomarkers in non-invasive detection of the disease.
Santosh K Patnaik, Sai Yendamuri, Eric Kannisto, John C Kucharczuk, Sunil Singhal, Anil Vachani   +5 more
doaj   +1 more source

miR449_string_hires_image-5-miR-449-miR-34.png

, 2023
miR449_string_hires_image-5-miR-449-miR-34 ...
Federica Monaco (17674014)
core   +1 more source

Exogenous expression of miR-630 inhibits the growth of PC-3 cells.

, 2014
A, confirmation by qRT-PCR of the successful overexpression of exogenous miR-630 from the pEP-hsa-miR-630 expression vector in PC-3 cells. The data are represented as the mean ± SEM of n = 3 independent experiments.
Takao Inoue (244518), Minami A. Sakurai (201488), Man Hagiyama (588612), Norikazu Yabuta (201494), Yuki Ozaki (589942), Ayumi Okamoto (589944), Hiroe Tabara (201481), Yoko Naito (201483), Daisuke Okuzaki (482418), Hiroshi Nojima (201497), Towa Sasakura (589943), Akihiko Ito (201485)   +11 more
core   +1 more source

miR-630 expression levels reduced after radiation.

, 2015
(A and B) Endogenous miR-630 expression and IR-induced inhibition rate of serial CRC cell lines (C) miR-630 level decrease after radiation compared with their initial level.
Guoxin Li (291236), Yan Zhang (8098), Jiefu Wang (782097), Wenhui Ma (427508), Li Yan (107001), Jiang Yu (427506), Hao Liu (12832)   +6 more
core   +1 more source

Dysregulation of circRNA-0076906 and circRNA-0134944 is Correlated with Susceptibility to Osteoporosis and Osteoporotic Fracture in Postmenopausal Females from the Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2023
Weijie Yang,* Wei Zhang,* Fengqian Li, Ning Xu, Ping Sun Department of Orthopedics, Shanghai Eighth People’s Hospital, Shanghai, 200235, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ping Sun ...
Yang W, Zhang W, Li F, Xu N, Sun P
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