Results 1 to 10 of about 3,028 (210)

miR-940 is a new biomarker with tumor diagnostic and prognostic value [PDF]

Molecular Therapy: Nucleic Acids, 2021
miR-940 is a microRNA located on chromosome 16p13.3, which has varying degrees of expression imbalance in many diseases. It binds to the 3′ untranslated region (UTR) and affects the transcription or post-transcriptional regulation of target protein ...
Hongxiang Li, Yin Li, Dongmei Tian, Jiaqian Zhang, Shiwei Duan   +4 more
doaj   +5 more sources

Optimization of a method for the clinical detection of serum exosomal miR-940 as a potential biomarker of breast cancer [PDF]

Frontiers in Oncology, 2022
Serum exosomal microRNAs (miRNAs) are potential biomarkers for tumor diagnosis. Clinically, reverse transcription-quantitative polymerase chain reaction (RT−qPCR) can be used to determine the expression of exosomal miRNAs in the serum of breast cancer ...
Zhiyun Gu, Zhiyun Gu, Haojie Yin, Haiwei Zhang, Haiwei Zhang, Hui Zhang, Hui Zhang, Xiaoyu Liu, Xiaoyu Liu, Xiaohua Zeng, Xiaohua Zeng, Xiaodong Zheng, Xiaodong Zheng, Xiaodong Zheng   +13 more
doaj   +4 more sources

Hsa_circ_0062682 Promotes Serine Metabolism and Tumor Growth in Colorectal Cancer by Regulating the miR-940/PHGDH Axis [PDF]

Frontiers in Cell and Developmental Biology, 2021
Colorectal cancer (CRC) is one of the most common malignancies globally. Increasing evidence indicates that circular RNAs (circRNAs) play a pivotal role in various cancers. The present study focused on exploring the role of a functionally unknown circRNA,
Shengbai Sun, Shengbai Sun, Chaoqun Li, Chaoqun Li, Kaisa Cui, Kaisa Cui, Bingxin Liu, Bingxin Liu, Mingyue Zhou, Mingyue Zhou, Yulin Cao, Yulin Cao, Jia Zhang, Jia Zhang, Zehua Bian, Zehua Bian, Bojian Fei, Zhaohui Huang, Zhaohui Huang   +18 more
doaj   +6 more sources

The circular RNA circ_0099630/miR-940/receptor-associated factor 6 regulation cascade modulates the pathogenesis of periodontitis [PDF]

Journal of Dental Sciences, 2022
Background/purpose: Periodontitis is one of the highly prevalent chronic inflammatory conditions in adults. The importance of circular RNAs (circRNAs) in the regulation of inflammation has been gradually reported in recent years, but the role of circRNA ...
Xue-Qin Zhao, Chuan-Bei Ao, Yi-Tong Yan
doaj   +4 more sources

circACTG1 Promotes Hepatocellular Carcinoma Progression by Regulating miR-940/RIF1 Axis and Activating AKT/mTOR Pathway [PDF]

Journal of Immunology Research, 2022
Background. Hepatocellular carcinoma (HCC) is recognized as the fourth in incidence and the third in mortality worldwide. The onset of HCC is insidious and often asymptomatic at the early stage.
Chunchen Wu, She Tian, Yuting Guo, Chao Yu, Linhan Lei, Dijie Zheng, Huahua Xie, Jian Zheng, Chengyi Sun   +8 more
doaj   +4 more sources

Circ_0003340 downregulation mitigates esophageal squamous cell carcinoma progression by targeting miR‐940/PRKAA1 axis [PDF]

Thoracic Cancer, 2022
Background Esophageal squamous cell carcinoma (ESCC) is a highly prevalent type of esophageal cancer (EC), usually found at an advanced stage with a high mortality rate, and it is now crucial to find new ways to diagnose and treat ESCC.
Xingzhuo Guan, Xiaohui Guan, Yuanshi Wang, Tingzhu Lan, Tongshuang Cheng, Yan Cui, Hongjun Xu   +6 more
doaj   +2 more sources

MiR-940 Inhibited Pancreatic Ductal Adenocarcinoma Growth by Targeting MyD88 [PDF]

Cellular Physiology and Biochemistry, 2015
Background: Pancreatic ductal adenocarcinoma (PDAC) is an almost universally lethal disease. Deregulation or dysfunction of miRNAs contribute to cancer development. The role of miR-940 in PDAC remains unclear.
Bin Song, Chaoxiong Zhang, Gang Li, Gang Jin, Cong Liu   +4 more
doaj   +3 more sources

MicroRNA-940 as a Potential Serum Biomarker for Prostate Cancer

Frontiers in Oncology, 2021
Prostate cancer is one of the leading causes of death despite an astoundingly high survival rate for localized tumors. Though prostate specific antigen (PSA) test, performed in conjunction with digital rectal examinations, is reasonably accurate, there ...
Smrithi Rajendiran, Sayantan Maji, Ahmed Haddad, Yair Lotan, Rajesh R. Nandy, Jamboor K. Vishwanatha, Jamboor K. Vishwanatha, Pankaj Chaudhary, Pankaj Chaudhary   +8 more
doaj   +1 more source

Unique microRNA expression profiles in plasmic exosomes from intrahepatic cholestasis of pregnancy

BMC Pregnancy and Childbirth, 2023
Background Intrahepatic cholestasis of pregnancy (ICP) is strongly associated with an increased risk of adverse perinatal outcomes. Total bile acid (TBA) levels in the late second or third trimester are a major factor in the diagnosis. Here, we sought to
Yao Kong, Yongchi Zhan, Daijuan Chen, Xixi Deng, Xinghui Liu, Tingting Xu, Xiaodong Wang   +6 more
doaj   +1 more source

Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus

BMC Medical Genomics, 2023
Background Adult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell leukemia virus type 1 (HTLV-1).
Mohadeseh Zarei Ghobadi, Elaheh Afsaneh, Rahman Emamzadeh, Mona Soroush   +3 more
doaj   +1 more source