Journal of Cellular and Molecular Medicine, 2018 AbstractWe previously demonstrated that acidic bile activates NF‐κB, deregulating the expression of oncogenic miRNA markers, in pre‐malignant murine laryngopharyngeal mucosa. Here, we hypothesize that the in vitro exposure of human hypopharyngeal cells to acidic bile deregulates cancer‐related miRNA markers that can be reversed by BAY 11‐7082, a ...
Sotirios G. Doukas +2 more
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Predicting the risk of malignisation of endometrial hyperplasia in reproductive age
Фундаментальная и клиническая медицина, 2020 Aim. Atypical endometrial hyperplasia (AEH) is a strong predictor of endometrial cancer, which is responsible for 80% of endometrial malignancies; out of all patients AEH, 10-50% are further diagnosed with endometrial cancer.
I. M. Ordiyants +3 more
doaj +1 more source
The ٍeffect of Eight Weeks of Moderate and High Intensity Resistance Training on micro-RNAs Associated with Reverse Cholesterol Transport in Older Wistar rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2019 Purpose: Aging is associated with systemic dysfunctions in lipid metabolism and chronic inflammatory state which contribute to atherosclerotic. The purpose of this study was to investigate the effect of moderate and high intensity resistance training on ...
mehdi taheri gandomany +3 more
doaj +1 more source
MicroRNA-23a promotes myelination in the central nervous system. [PDF]
, 2013 Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui +5 more
core +2 more sources
Diagnostic Potential of miR-126, miR-143, miR-145, and miR-652 in Malignant Pleural Mesothelioma [PDF]
The Journal of Molecular Diagnostics, 2014 Malignant pleural mesothelioma (MPM) is difficult to distinguish from reactive mesothelial proliferations (RMPs). It is uncertain whether miRNAs are useful biomarkers for differentiating MPM from RMPs. Thus, we screened with a quantitative RT-PCR (RT-qPCR)-based platform the expression of 742 miRNAs in formalin-fixed, paraffin-embedded, preoperative ...
Andersen, Morten +5 more
openaire +3 more sources
Mechanisms of action of extracellular miRNAs
Zdorovʹe Rebenka, 2022 The mechanisms of action of extracellular miRNAs are given in the scientific review. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library databases.
A.E. Abaturov, V.L. Babуch
doaj +1 more source
The \u3cem\u3emir-51\u3c/em\u3e Family of MicroRNAs Functions in Diverse Regulatory Pathways in \u3cem\u3eCaenorhbditis elegans\u3c/em\u3e [PDF]
, 2012 The mir-51 family of microRNAs (miRNAs) in C. elegans are part of the deeply conserved miR-99/100 family. While loss of all six family members (mir-51-56) in C. elegans results in embryonic lethality, loss of individual mir-51 family members results in a
Abbott, Allison L. +2 more
core +1 more source
Circulating micrornas associated with glycemic impairment and progression in Asian Indians. [PDF]
, 2015 Aims/hypothesisAsian Indians have a high incidence of type 2 diabetes, but factors associated with glycemic progression in this population are not understood.
Aouizerat, Bradley E +3 more
core +1 more source
Physiological Reports, Volume 13, Issue 15, August 2025.Abstract MicroRNAs (miRs) regulate the translation of target genes often in a cell‐type specific manner. We previously demonstrated that downregulation of either miR‐181a or miR‐200c with intracranial injection of an inhibitor is protective against experimental stroke in mice.
Lijun Xu +9 more
wiley +1 more source
The role of miR-24 as a race related genetic factor in prostate cancer. [PDF]
, 2017 The incidence of prostate cancer (PCa) among African-Americans (AfA) is significantly higher than Caucasian-Americans (CaA) but the genetic basis for this disparity is not known.
Dahiya, Rajvir +15 more
core +1 more source