miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development [PDF]
, 2015 MicroRNAs play a crucial role in the regulation of cell growth and differentiation. Mice with genetic deletion of miR-375 exhibit impaired glycemic control due to decreased β-cell and increased α-cell mass and function.
Herrmanns, K +8 more
core +2 more sources
MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome [PDF]
Nucleic Acids Research, 2020 Abstract Many microRNAs regulate gene expression via atypical mechanisms, which are difficult to discern using native cross-linking methods. To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA.
Wang, Yuluan +8 more
openaire +6 more sources
The mid-infrared view of red sequence galaxies in Abell 2218 with AKARI [PDF]
, 2009 We present the AKARI Infrared Camera (IRC) imaging observation of early-type galaxies (ETGs) in A2218 at z ~ 0.175. Mid-infrared (MIR) emission from ETGs traces circumstellar dust emission from asymptotic giant branch (AGB) stars or/and residual star ...
Bower +39 more
core +3 more sources
Let it glow: genetically encoded fluorescent reporters in Plasmodium
Malaria JournalThe use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein (GFP) enabled to explore protein localization, promoter activity as well
Pia J. Thiele +3 more
doaj +1 more source
Klasik ve Modern Dönemde Yazılmış İki Usûlün (Mir'âtü'l-Uṣûl ile Uṣûlü’l-Fıkh) Mukayesesi
Tokat İlmiyat Dergisi, 2021 Fıkhın kaynaklarını ve temellerini, bunlardan hüküm çıkarma yöntemlerini konu alan fıkıh usulü ilmi ilk defa Müslümanlar tarafından oluşturulmuş ve geliştirilmiş özgün bir ilim dalıdır. Bu ilme dair günümüze kadar pek çok eser kaleme alınmıştır.
Hilal Özay, Hatice Esra Can
doaj +1 more source
Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. [PDF]
, 2015 BACKGROUND: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency.
Alder, Hansjuerg +14 more
core +1 more source
La artrodesis de las cuatro esquinas con placa circular
Revista Iberoamericana de Cirugía de la Mano, 2007 Objetivo: La artrodesis de las cuatro esquinas del carpo fue descrita inicialmente para el tratamiento del colapso avanzado del carpo e incluye la extirpación del escafoides y la fusión de los huesos semilunar, piramidal, hueso grande y ...
A. García López +4 more
doaj +1 more source
Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring [PDF]
, 2009 Background miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during ...
Bruce, Kimberley D. +9 more
core +3 more sources
Avances del Cesor, 2017 El Movimiento de Izquierda Revolucionaria (MIR), de Chile, fundado en 1965, se convirtió entre las décadas de 1960 y 1980, en la principal organización de la izquierda armada del país.
Igor Goicovic Donoso
doaj +1 more source
Regulation of metabolism by miR-378 [PDF]
, 2014 The present invention provides a method of regulating fatty acid metabolism in a cell by contacting the cell with a modulator of miR-378 and/or miR-378* activity or expression.
Carrer, Michele, Olson, Eric N.
core +1 more source