Results 31 to 40 of about 447,640 (362)
Acta Agriculturae Slovenica, 2014 Tobacco leaf explants were transformed by bacteria Agrobacterium tumefaciens (A. t.) and plasmid pBIN mgfp5-ER, which has a single copy of the green fluorescent gfp gene and A. t.-pART27 2mgfp5-ER, which has two copies of the gfp gene. Both plasmids have
Niko PAVLIN, Zlata LUTHAR
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Cells, 2020 In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC).
Lisa Linck-Paulus +3 more
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Nature Communications, 2017 Core clock genes, such asBmal1, are expressed in astrocytes, but their contribution to the timekeeping system is unknown. Barca-Mayo et al. report that deletion of Bmal1in Glast+ astrocytes alters the neuronal clock through GABA signalling, leading to ...
Olga Barca-Mayo +5 more
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DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions
Nucleic Acids Res., 2017 DIANA-TarBase v8 (http://www.microrna.gr/tarbase) is a reference database devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth version is the first database indexing >1 million entries, corresponding to ∼670 000 unique
Dimitra Karagkouni +12 more
semanticscholar +1 more source
Frontiers in Neuroscience, 2018 DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these
Nadin Hoffmann +4 more
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NGR4 and ERBB4 as Promising Diagnostic and Therapeutic Targets for Metabolic Disorders
Frontiers in Bioscience-Elite, 2023 Obese individuals are at high risk for developing type 2 diabetes mellitus, cardiovascular diseases, and nonalcoholic fatty liver disease. The aim of this review was to analyze the scientific literature and databases to reveal the fundamental role of ...
Maria Vulf +10 more
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Trends in the development of miRNA bioinformatics tools
Briefings Bioinform., 2019 MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via recognition of cognate sequences and interference of transcriptional, translational or epigenetic processes.
Liang Chen +5 more
semanticscholar +1 more source
Cancers, 2021 Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several treatment options are available including surgery, along with adjuvant chemo and radiotherapy, the disease has a poor prognosis and patients generally die within 14 months of diagnosis. GB is chemo and radio resistant.
Swalih P. Ahmed +2 more
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The importance of training in contemporary organizations
Mенаџмент у хотелијерству и туризму, 2019 This paper describes the concepts of training and career development for employees, level of knowledge of workers, the profit that some companies had from continuous training, and the way in which an organizational psychologist, with the support of ...
Ana Slavković, Vukan Slavković
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MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme
Cancer Biology & Medicine, 2020 Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire resistance towards anoikis during tumorigenesis to become ...
Sharan Malagobadan +2 more
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