Results 31 to 40 of about 487,200 (353)
Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma
Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular ...
Katar, Salim+8 more
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The singular world of singular cardinals [PDF]
The article uses two examples to explore the statement that, contrary to the common wisdom, the properties of singular cardinals are actually more intuitive than those of the regular ...
Dzamonja, Mirna
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Using miRNA-Analyzer for the Analysis of miRNA Data [PDF]
MicroRNAs (miRNAs) are small biological molecules that play an important role during the mechanisms of protein formation. Recent findings have demonstrated that they act as both positive and negative regulators of protein formation. Thus, the investigation of miRNAs, i.e., the determination of their level of expression, has developed a huge interest in
Pietro Guzzi+2 more
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miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]
ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory+31 more
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miR-30b-5p targeting GRIN2A inhibits hippocampal damage in epilepsy
GRIN2A is associated with epilepsy (EP); however, its regulatory mechanism involving upstream miRNA (miR-30b-5p) has been overlooked. In this study, we aimed to identify the regulatory mechanism of the miR-30b-5p/GRIN2A axis in EP.
Zheng Hu, Wu Liuyang, Yuan Huisheng
doaj +1 more source
Representation of an absent space: construction of the United States and New York in 1950s and 1960s Czech travel writing [PDF]
Early postwar Czech travel writing was mainly concerned with representations of countries from the newly emerging Soviet Bloc and former European colonies in the developing world.
Solic, Mirna
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Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Puri Fortes+2 more
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Tobacco leaf explants were transformed by bacteria Agrobacterium tumefaciens (A. t.) and plasmid pBIN mgfp5-ER, which has a single copy of the green fluorescent gfp gene and A. t.-pART27 2mgfp5-ER, which has two copies of the gfp gene. Both plasmids have
Niko PAVLIN, Zlata LUTHAR
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MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Xiao-Lei Hu+7 more
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DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these
Nadin Hoffmann+4 more
doaj +1 more source