The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
, 2011 Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011 Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena +2 more
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ŽUPANČIČEVA ZAPUŠČINA IN NJEGOVA OSEBNA KNJIŽNICA
Knjižnica, 2015 Zapuščina književnika Otona Župančiča, ki jo je Mestnemu muzeju Ljubljana leta 1985 z darilno pogodbo izročila umetnikova družina, sodi med redke tako obsežne in raznovrstne umetniške zapuščine.
Dragica Trobec Zadnik +1 more
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MicroRNA-29 family expression and its relation to antiviral immune response and viro-immunological markers in HIV-1-infected patients [PDF]
, 2015 BACKGROUND: Several in vitro studies suggested the microRNA-29 (miRNA-29) family is involved in regulating HIV-1 and modulating the expression of interleukin (IL)-32, an anti-HIV-1 cytokine.
ANTONELLI, Guido +9 more
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BMC Medical Research Methodology, 2019 Background Reporting quality of systematic reviews’ (SRs) abstracts is important because this is often the only information about a study that readers have. The aim of this study was to assess adherence of SR abstracts in the field of anesthesiology with
Katarina Maticic +2 more
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Disease Models & Mechanisms, 2021 Facioscapulohumeral muscular dystrophy (FSHD) is caused by misexpression of DUX4 in skeletal myocytes. As DUX4 is the key therapeutic target in FSHD, surrogate biomarkers of DUX4 expression in skeletal muscle are critically needed for clinical trials ...
Andreia M. Nunes +3 more
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microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]
, 2014 BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P +5 more
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Identification of regulatory pathways of miRna and phasiRna related to flax lignan synthesis
Journal of Natural Fibers, 2023 Lignan is an important functional health care substance. At present, research on the molecular mechanism of flax lignan biosynthesis is primarily focused at the transcriptional level, with no research on the regulatory mechanism of small RNAs ...
Dongwei Xie +8 more
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Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]
, 2020 microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha +4 more
core
Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs [PDF]
, 2017 Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods ...
Dinh-Toi Chu, Dinh-Toi Chu +4 more
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