Results 101 to 110 of about 287,756 (317)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Bioinformatic analysis of four miRNAs relevant to metastasis-regulated processes in endometrial carcinoma [PDF]

, 2018
Lingping Zhu,1,2 Zhiqun Shu,3 Xiaoming Sun2,3 1Department of General Practice, Shenzhen Longhua District Central Hospital, Shenzhen, People’s Republic of China; 2Department of General Practice, Zhongshan Hospital, Fudan University, Shanghai, People&
Shun X, Zhu L, Shu Z
core  

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Identification and Validation of Key miRNAs for Colon Cancer Based on miRNA-Gene Integration Analysis [PDF]

, 2023
Yi Ji,1,* Jialin Gu,1,2,* Hongqun Zhang,1,2 Houxi Xu3 1Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, People’s Republic of China; 2The Third Clinical Medical ...
Zhang H, Gu J, Ji Y, Xu H
core  

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection

Advanced Materials, EarlyView.
The intimate interaction between negatively charged RNA molecules and conjugated polymers in organic electrochemical transistors (OECTs) in aqueous electrolytes is investigated. It demonstrates that RNA binding reduces the volumetric capacitance of the polymer channel, enabling the development of an ultrasensitive biosensing platform capable of ...
Hong Liu, Naixiang Wang, Anneng Yang, Jiajun Song, Li Li, Iain McCulloch, Helen Ka‐wai Law, Feng Yan   +7 more
wiley   +1 more source

Profiling of miRNAs in pediatric asthma: Upregulation of miRNA-221 and miRNA-485-3p

Molecular Medicine Reports, 2012
The aim of this study was to investigate the expression profiles of microRNAs (miRNAs) in pediatric asthma and to determine candidate miRNAs responsible for the pathogenesis of this disease. Microarrays were used to detect the differences in the miRNA expression levels between asthmatic children and controls. Airway
Feng, Liu, Hou-Bing, Qin, Bing, Xu, Hui, Zhou, De-Yu, Zhao   +4 more
openaire   +3 more sources

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Mechanisms of miRNAs and their expression in gastric cancer [PDF]

Archives of Razi Institute
Gastric cancer is the fourth most common cancer in the world and the second leading cause of cancer-related deaths worldwide. Gastric cancer was responsible for approximately 768,000 deaths.
Tahereh Eslammanesh, Afsaneh Mirshekari, Narjes Dahmardeh, Mehrangiz Ghafari, Fatemeh Mahmoodi, Mehdi Jahantigh, Ali Reza Mirzaei, Bahman Fazeli-Nasab   +7 more
doaj   +1 more source

miRNAs in head and neck cancer revisited [PDF]

, 2013
Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cause of cancer mortality in the world and the 5th most commonly occurring cancer.
Cooper-White, Justin, Nagadia, Rahul, Pandit, P., Punyadeera, Chamindie, Coman, William B, Pandit, Pratibala, Coman, William B., Cooper-White, J., Nagadia, R., Coman, W. B.   +9 more
core   +1 more source

miRNA target prediction through mining of miRNA relationships

2008 8th IEEE International Conference on BioInformatics and BioEngineering, 2008
miRNAs are small regulators that mediate gene expression and each miRNA regulates specific target genes. In animals, target prediction of the miRNAs is accomplished through several computational methods, i.e. miRanda, TargetScan and PicTar.
Zhang, Y., Bruin, J.S. de, Verbeek, F.J.
openaire   +2 more sources