Results 11 to 20 of about 563,981 (384)
Deciphering miRNAs’ Action through miRNA Editing [PDF]
International Journal of Molecular Sciences, 2019 MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation.
M. Correia de Sousa +4 more
semanticscholar +4 more sources
miRNAs: Potential as Biomarkers and Therapeutic Targets for Cancer
Genes, 2023 MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to messenger RNAs. miRNAs are important regulators of gene expression, and their dysregulation is implicated in many human ...
Atonu Chakrabortty +3 more
semanticscholar +1 more source
miRNAs in Cancer (Review of Literature)
International Journal of Molecular Sciences, 2022 MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate gene expression at the post-transcriptional level by binding to mRNAs.
B. Smolarz +4 more
semanticscholar +1 more source
The role of Exosomal miRNAs in cancer
Journal of Translational Medicine, 2022 Exosomal miRNAs have attracted much attention due to their critical role in regulating genes and the altered expression of miRNAs in virtually all cancers affecting humans (Sun et al. in Mol Cancer 17(1):14, 2018). Exosomal miRNAs modulate processes that
Chuanyun Li +8 more
semanticscholar +1 more source
Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions [PDF]
BioMed Research International, 2014 MicroRNAs (miRNAs) are small, noncoding regulatory molecules. They are involved in many essential biological processes and act by suppressing gene expression. The present work reports an integrative analysis of miRNA-mRNA and miRNA-miRNA interactions and their regulatory patterns using high-throughput miRNA and mRNA datasets. Aberrantly expressed miRNA
Guo, Li +4 more
openaire +2 more sources
Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis
Frontiers in Immunology, 2021 This mini-review summarizes the current evidence for the role of macrophage activation and polarization in inflammation and immune response pertinent to interstitial lung disease, specifically pulmonary fibrosis. In the fibrosing lung, the production and
A. Kishore, M. Petrek
semanticscholar +1 more source
Emerging roles of exosomal miRNAs in diabetes mellitus
Clinical and Translational Medicine, 2021 Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids, proteins, and metabolites. Exosomes transfer substances and information between cells
Xiaoyun He +3 more
semanticscholar +1 more source
miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis
Cells, 2020 MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of regulating mRNA through its degradation and adjusting protein levels. In recent years, extraordinary progress has been made in terms of identifying the origin and exact
C. Condrat +8 more
semanticscholar +1 more source
Expression, regulation, and function of exosome‐derived miRNAs in cancer progression and therapy
The FASEB Journal, 2021 Exosomes are a novel class of intercellular signal modulators that contain a wide range of molecules and deliver information between cells and tissues.
Bowen Li, Yu Cao, Mingjun Sun, H. Feng
semanticscholar +1 more source
Targeted oncology, 2020 Non-coding RNAs represent a significant proportion of the human genome. After having been considered as ‘junk’ for a long time, non-coding RNAs are now well established as playing important roles in maintaining cellular homeostasis and functions.
M. Ratti +6 more
semanticscholar +1 more source