Results 11 to 20 of about 360,344 (284)

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer [PDF]

Frontiers in Oncology, 2015
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures. Accumulating evidence indicates that miRNA expression patterns represent the in vivo status in physiology and
Xin eQin, Haisheng eXu, Wenrong eGong, Wenbin eDeng, Wenbin eDeng   +4 more
openaire   +9 more sources

Deciphering miRNAs’ Action through miRNA Editing [PDF]

International Journal of Molecular Sciences, 2019
MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation. The outcome of a myriad of physiological processes and pathologies, including cancer, cardiovascular and metabolic diseases, relies ...
Correia De Sousa, Marta, Gjorgjieva, Monika, Dolicka, Dobrochna, Sobolewski, Cyril, Foti, Michelangelo   +4 more
openaire   +3 more sources

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions [PDF]

BioMed Research International, 2014
MicroRNAs (miRNAs) are small, noncoding regulatory molecules. They are involved in many essential biological processes and act by suppressing gene expression. The present work reports an integrative analysis of miRNA-mRNA and miRNA-miRNA interactions and their regulatory patterns using high-throughput miRNA and mRNA datasets. Aberrantly expressed miRNA
Guo, Li, Zhao, Yang, Yang, Sheng, Zhang, Hui, Chen, Feng   +4 more
openaire   +2 more sources

Regulation of miRNA content. Part 1. Editing miRNA. Тailing miRNA

CHILD`S HEALTH, 2022
This scientific review presents the processes of regulation of miRNA content. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases.
A.E. Abaturov, V.L. Babуch
openaire   +4 more sources

MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]

International Journal of Environmental Research and Public Health, 2016
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng, Hu, Yao-Dong, Hu, Xiao-Lei, Zhang, Yan-Jiao, Yang, Yong-Long, Jiang, Chun, Tang, Jie, Chen, Xiao-Ping   +7 more
openaire   +2 more sources

Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]

, 2016
Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C., Nasir, L., Nicolson, L., Terron-Canedo, N., Weir, W.   +4 more
core   +1 more source

Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs [PDF]

, 2017
Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods ...
Dinh-Toi Chu, Dinh-Toi Chu, Duc-Hau Le, Duc-Hau Le, Le Hoang Son, Le Hoang Son, Van-Huy Pham, Van-Huy Pham, Verbeke, Lieven   +4 more
core   +2 more sources

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
core   +2 more sources

miRNA biomarkers in colon cancer liver metastasis: a preliminary analysis

结直肠肛门外科, 2022
[Objectives] To identify miRNAs associated with colon cancer liver metastasis and their influences on survival. [Methods] The study compared the miRNAs data sets of primary colon cancer tissues and liver metastasis tissues from colon cancer patients with
Fu Tianhao, Liao Xiwen, Zhou Xin, Wang Xiangkun, Liu Junqi, Wei Zhongliu, Zhu Guangzhi, Gong Yizhen, Peng Tao   +8 more
doaj   +1 more source

MicroRNAs in melanoma development and resistance to target therapy [PDF]

, 2017
microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio, Ciliberto, Gennaro, Costantini, Susan, Croce, Carlo M, Fattore, Luigi, Malpicci, Debora, Mancini, Rita, Ruggiero, Ciro Francesco   +7 more
core   +1 more source