Regulation of miRNA content. Part 1. Editing miRNA. Тailing miRNA
CHILD`S HEALTH, 2022 This scientific review presents the processes of regulation of miRNA content. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases.
A.E. Abaturov, V.L. Babуch
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MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]
International Journal of Environmental Research and Public Health, 2016 Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng +7 more
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Adipose-Derived Circulating miRNAs Regulate Gene Expression in Other Tissues
Nature, 2017 Adipose tissue is a major site of energy storage and has a role in the regulation of metabolism through the release of adipokines. Here we show that mice with an adipose-tissue-specific knockout of the microRNA (miRNA)-processing enzyme Dicer (ADicerKO),
Thomas Thomou +12 more
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MiRNAs and Cancer: Key Link in Diagnosis and Therapy
Genes, 2021 Since the discovery of the first microRNA (miRNA), the exploration of miRNA biology has come to a new era in recent decades. Monumental studies have proven that miRNAs can be dysregulated in different types of cancers and the roles of miRNAs turn out to ...
Yu Shi +7 more
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Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]
, 2016 Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C. +4 more
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Mitochondrial Quality Control: the Role in Cardiac Injury
Frontiers in Bioscience-Landmark, 2022 The heart is a highly energy-dependent organ, and most of its energy is provided by mitochondrial oxidative phosphorylation. Therefore, maintaining a well-functioning mitochondrial population is of paramount importance for cardiac homeostasis, since ...
Grażyna Sygitowicz, Dariusz Sitkiewicz
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Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs [PDF]
, 2017 Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods ...
Dinh-Toi Chu, Dinh-Toi Chu +4 more
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Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]
, 2017 Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma +59 more
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miRNA biomarkers in colon cancer liver metastasis: a preliminary analysis
结直肠肛门外科, 2022 [Objectives] To identify miRNAs associated with colon cancer liver metastasis and their influences on survival. [Methods] The study compared the miRNAs data sets of primary colon cancer tissues and liver metastasis tissues from colon cancer patients with
Fu Tianhao +8 more
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Exosome-mediated delivery of gga-miR-20a-5p regulates immune response of chicken macrophages by targeting IFNGR2, MAPK1, MAP3K5, and MAP3K14 [PDF]
Animal Bioscience, 2023 Objective This study aims to evaluate the target genes of gga-miR-20a-5p and the regulated immune responses in the chicken macrophage cell line, HD11, by the exosome-mediated delivery of miR-20a-5p.
Yeojin Hong +5 more
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