Results 41 to 50 of about 563,981 (384)
Cancers, 2021 Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several treatment options are available including surgery, along with adjuvant chemo and radiotherapy, the disease has a poor prognosis and patients generally die within 14 months of diagnosis. GB is chemo and radio resistant.
Swalih P. Ahmed +2 more
openaire +3 more sources
Computational and Experimental Tools of miRNAs in Cancer [PDF]
Middle East Journal of Cancer, 2020 MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA molecules with a critical role in the regulation of gene expression.
Esen Çakmak
doaj +1 more source
Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities [PDF]
Advanced Pharmaceutical Bulletin, 2021 Colorectal cancer (CRC) is one of the most disseminated diseases across the globe engaging the digestive system. Various therapeutic methods from traditional to the state-of-the-art ones have been applied in CRC patients, however, the attempts have been ...
Amir Mehrgou +7 more
doaj +1 more source
Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation [PDF]
, 2017 Epigenetics plays a pivotal role in regulating gene expression in development, in response to cellular stress or in disease states, in virtually all cell types.
Adamo, Sergio +3 more
core +1 more source
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011 Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena +2 more
openaire +2 more sources
Dysregulated placental microRNAs in Early and Late onset Preeclampsia [PDF]
, 2018 Copyright © 2017. Published by Elsevier Ltd.INTRODUCTION: To determine the miRNA expression profile in placentas complicated by Preeclampsia (PE) and compare it to uncomplicated pregnancies.
Braoudaki, Maria +8 more
core +2 more sources
Functional Genomics Profiling of Bladder Urothelial Carcinoma MicroRNAome as a Potential Biomarker. [PDF]
, 2018 Though bladder urothelial carcinoma is the most common form of bladder cancer, advances in its diagnosis and treatment have been modest in the past few decades.
Li, Wei Tse +4 more
core +2 more sources
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
Acta Pharmacologica Sinica, 2018 Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the world. Although considerable progress has been made in the diagnosis, treatment and prognosis of CVD, there is still a critical need for novel diagnostic biomarkers and
Shanshan Zhou +6 more
semanticscholar +1 more source
Linc-smad7 promotes myoblast differentiation and muscle regeneration via sponging miR-125b
Epigenetics, 2018 Long noncoding RNAs (lncRNAs) are involved in the regulation of skeletal muscle development. In the present study, differentially expressed lncRNAs were identified from RNA-seq data derived from myoblasts and myotubes.
Chengchuang Song +10 more
doaj +1 more source
European Journal of Biology, 2021 Objective: Despite advances in treatment approaches, metastatic castration-resistant prostate cancer (mCRPC) remains a clinical challenge to treat. Cabazitaxel (Cab), a third-line chemotherapy option for mCRPC, exhibits limited efficiency due to the ...
Işıl Ezgi Eryılmaz +4 more
doaj +1 more source